M-CSF (CSF1) (NM_000757) Human Recombinant Protein

CAT#: TP317104

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Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 1


 Product Datasheet for 'TP317104'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 1
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 59.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000748
Locus ID 1435
Refseq Size 4249
Cytogenetics 1p13.3
Refseq ORF 1662
Synonyms CSF-1; MCSF
Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage

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