Gene editing with CRISPR-CAS9 kits

What is CRISPR CAS9?

CRISPR/Cas9, is an RNA-guided targeted genome editing tool which allows researchers to do gene knockout, knockin SNPs, insertions and deletions in cell lines and animals. The CRISPR/Cas9 genome editing system requires two components: Cas9, the endonuclease, and a guide RNA (sgRNA) which guides Cas9 to a specific location in the genome sequence. With the protospacer-adjacent motif (PAM - the sequence NGG) present at the 3′ end, Cas9 will unwind the DNA duplex and cleave both strands upon recognition of a target sequence by the guide RNA.

Products and Services

OriGene provides reagents to support a broad range of CRISPR/Cas9 gene editing applications. Click the following gene editing related product below and learn more about how we can help you.

CRISPR Resources

References