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B-cell lineage marker
MAGE-A family are part of the cancer-testis antigens whose limited expression in normal tissues and high expression in cancer makes them excellent targets for immunotherapy. Clinical trials have already begun targeting MAGE-A3 and MAGE-A4 proteins in lung cancer tumors. A recent study showed that MAGEA3 & MAGEA4 could be co-expressed in lung cancer. Learn more »
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