HuSH-29™: shRNA for Human, Mouse and Rat Genes

OriGene uses a 29-mer short hairpin design for Hush-29TM shRNA plasmids, which has been demonstrated to be more effective than 21-mer designs (learn more about the design algorithm). Pre-designed Hush-29 shRNAs offer genome-wide coverage for human, mouse and rat genes with a guaranteed knockdown of ≥70%. View citations.

HuSH-29TM shRNA Features

Lenti-shRNA Particle Offering    Lenti virus

  • Coverage: any shRNA targeting human, mouse or rat genes
  • Read-to-use: just add to your cells and assay
  • Broad spectrum: Transduce both dividing and non-dividing cells
  • Biosafety: replication-deficient 3rd generation lenti particles
  • Other Lentiviral Products
  • Custom lentivirus services: Ultra high titer and flexible scales

Featured Products

  • RNAi Validation Vector
    The RNAi Validation Vector is a fusion construct which incorporates a full length TrueClone and a luciferase reporter gene. By using this validation vector one can quickly find the effective knockdown construct as well as the optimal transfection conditions. Learn more...

    SKU Description Availability
    TR30004 Firefly Luciferase mammalian expression reporter vector In Stock
  • HuSH-29 shRNA Kinase Collection
    HuSH-29 Kinase Collection contains 481 genes cloned in pRFP-C-RS vector allowing researchers to monitor transfection. Learn more…

    SKU Description Availability
    TR100001 HuSH shRNA kinase collection in RFP vector - constructs individually plated (481 gene targets, 4 shRNA constructs per target, 2 ug/well) In Stock

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Use of this product is subject to a license from CSHL or Hairpin Technologies, and CSHL. Hairpin Technologies reserves all other rights under its license. For information on licensing rights for Commercial Entities, including use of this product for purposes other than research and trial licenses, please contact Hairpin Technologies, Inc. at or call (631) 881-0844.

Recent Citations using our shRNA products

1. Neuronal ER-plasma membrane junctions couple excitation to Ca 2+ -activated PKA signaling

Published in Nature Communications, 2023 Aug, using TL708390
PubMed: 37633939

2. α 1 -Adrenergic receptor–PKC–Pyk2–Src signaling boosts L-type Ca 2+ channel Ca V 1.2 activity and long-term potentiation in rodents

Published in eLife, 2023 Jun, using TL710108
PubMed: 37338965

3. THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme

Published in American Journal of Cancer Research, 2023 Jun, using TL301111
PubMed: 37424800

See all »