Viral Gene Delivery
What is a Viral Vector?
Viral Vectors are tools frequently used to deliver genetic material into cells. Lentiviral vectors (LV) and adeno-associated viral vectors (AAV) can deliver genetic material into dividing and non-dividing cells unlike other retroviral vectors. These two vectors remain the most popular options for gene delivery in both research and clinical applications. OriGene offers genome-wide lentiviral vectors, shRNA lentiviral products, AAV vectors, and more.
How do I decide which vector to use?
AAV vectors are smaller than LV vectors which results in better spreading efficiency in specific tissues. If you are looking to avoid interactions with other cells in the same tissue, LV vectors offer a solution, as they only target distinct cell populations. In addition, LV vectors have the ability to integrate into the host genome which provides stable expression, whereas AAV vectors stay in the episome within cells. There are pros and cons to each vector but deciding which to use, is completely dependent on your goal.
Features | Lentivirus | AAV |
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Larger insert size |
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Tissue Specificity |
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Genome Integration |
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Ideal for in-vivo use |
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Higher Titer |
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Viral Packaging
Viral packaging is a fundamental viral process that can be exploited to express your gene-of-interest in a cell population. OriGene provides custom AAV packaging as well as a lentiviral particle packaging kit which optimizes the packaging of 3rd generation lentivectors in viral particles.


Why Use OriGene?
- Broad cell spectrum: Between AAV and LV vectors, you can deliver genetic material of variable sizes to dividing and non-dividing cells.
- Multiple reporter options including GFP, RFP, and DDK
- Particles arrive transduction-ready