MicroRNA Expression Plasmids
MicroRNAs (miRNAs) are naturally occurring non-coding RNA molecules (containing 21-23 nucleotides) that function in RNA silencing and post-transcriptional regulation of gene expression.
OriGene provides clones that facilitate over-expression of the miRNA of your choice. A region of ~600bp encompassing each miRNA is cloned downstream of a CMV promoter. Upon transfection, the cellular machinery will process the CMV-driven expression of miRNA precursor into mature miRNA, and cellular function can be analyzed.
Key Features
- Genome-wide miRNA coverage (miRBase 20.0): 1829 human, 1160 mouse, 436 rat
- GFP reporter for transfection monitoring
- Neomycin selection marker for stable cell establishment
- 3' UTR reporter clones available for miRNA target validation
- Cloning Vector:
Bulk Order Options
The complete set of the miRNA expression plasmids is available upon inquiry. Any purchase of over 10 miRNA plasmids is qualified for discount. Please contact techsupport@origene.com for more details.
Recent Citations using our MicroRNA Expression Plasmids
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1 miR-155-5p can be involved in acquisition of osseointegration on titanium surface. Published in In vitro cellular & developmental biology , using |
PubMed: 36053380 |
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2 microRNA ‐29a Regulates ADAM12 Through Direct Interaction With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery Published in Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease , using |
PubMed: 35946473 |
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3 miR-637 Prevents Glioblastoma Progression by Interrupting ZEB2/WNT/β-catenin Cascades. Published in Cellular and molecular neurobiology , using |
PubMed: 34047878 |
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