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Antibody Drug Conjugates
Antibody-Drug Conjugates (ADCs) couple the precise targeting ability of monoclonal antibodies and the powerful effects of small-molecule cytotoxic drugs. This strategy enhances the precision of cancer treatments while reducing the unwanted side effects commonly seen with traditional therapies.
OriGene's Solution for ADC Research
We offer antibodies against Payloads, Linkers, as well as ADC internalization labeling kits. Using high-quality Antibodies and reagents, enhances the outcome of your research immensely.
Detect Payloads and Linkers with Confidence!
Detecting payloads and linkers is important as it ensures the stability, efficacy, and safety of the therapeutic compound. These components need to be tracked to verify the successful delivery and release of the payload at the target cell.
OriGene offers antibodies focusing on differents targets and goals.
ADC Internalization Labeling Reagents
The ADC internalization labeling reagents are essential tools for advancing your ADC research. Specifically designed for precision. Further, pH sensitive internalization reagents ensure that the reagents can effectively enter the target cells and release the drug payload at the desired intracellular pH. This specificity enhances the efficacy of the ADC's by minimizing offtarget effects and improving overall results.
Enhance your ADC development process with OriGene's comprehensive internalization labeling reagents for specific and reliable research results.
| Reagent Type | Product Number |
|---|---|
| ADC internalization pH sensitive IgG labeling reagent | |
| ADC internalization pH sensitive IgG labeling reagent plus | |
| ADC Internalization MMAE IgG labeling reagent |
Specific Internalization of GPRC5D ADC BMK-AR100090 Conjugate in GPRC5D-Positive Cells (K562-GPRC5D Stable Expression Cell Line, Right), with No Detection in K562 Cells Lacking GPRC5D Overexpression (Left).