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EV/Exosome
Immunocapture Kits

Validated performance, high specificity, and cleaner downstream EV preparation for sensitive applications

With validated high affinity antibodies coupled to magnetic beads (>90% high iron oxide beads), OriGene offers reliable and high specific capture of EV subpopulations from various biofluids, cell culture media.

>90%
Capture Efficiency
Low
Protein Carryover
Enriched
EV Markers
Broad
Sample Compatibility
Hero Image

Supporting Data

  • >90% capture efficiency of CD9⁺ and CD81⁺ EV subpopulations across multiple sample types.

    Graphs cd9-cd81-capture-efficiency
    Figure 1: Isolated CD9⁺ and CD81⁺ extracellular vesicles (EVs) were quantified using ELISA kits (catalog nos. EA200081 and EA200082), which demonstrated higher capture efficiency across multiple sample types.

  • Broader EV size capture coverage, Outperforms Competition

    Graph cd9-cd81-capture-efficiency
    Figure 2: Isolated CD9⁺ and CD81⁺ extracellular vesicles (EVs) were analyzed using NanoFCM. The results demonstrated broad EV size-range detection (right) and superior EV capture efficiency compared with Vendor T products (left) across multiple sample types.

  • Increased EV Market Yield, Outperforms Competition

    Graph ev-markers-and-cd81-enrichment
    Figure 3: Isolated CD9⁺ and CD81⁺ extracellular vesicles (EVs) exhibited expression of canonical EV markers, including TSG101, CD81, and CD63 (left). The image on the right demonstrates enhanced CD81 marker enrichment in CD9⁺ EVs compared with Vendor T across multiple sample types.

  • Cleaner EV Preparations for Sensitive Downstream Assays, Outperforms Competition

    Graph Cleaner EVs
    Figure 4: Isolated CD9⁺ EVs exhibited minimal carryover of abundant biofluid proteins, such as ApoE and albumin. In a head‑to‑head comparison with Vendor T, OriGene immunocapture beads achieved >80% removal of carryover proteins from plasma samples.

  • Abundant EV Cargo DNA Recovered Post-Bead Capture, Outperforms Competition

    Abundant EV Cargo DNA Image
    Figure 5: DNA was isolated from captured CD9⁺ EVs. In a head‑to‑head comparison with Vendor T, OriGene immunocapture beads demonstrated more than a two‑fold higher recovery of cargo DNA from captured CD9⁺ EVs.

  • Isolation of mouse derived EV using OriGene EV Capture Beads

    Nanoparticle Mouse EV Image
    Figure 6: EV harvested from the NIH/3T3 mouse fibroblast cell line were analyzed for particle concentration before immunocapture and in the post‑capture supernatant following CD81 and CD9 capture. Immunocapture beads demonstrated effective capture of mouse‑derived EVs.

Available Product Kits

Choose from our range of products optimized for different EV subpopulation isolations

SKU Name Reaction Cart
AR100094S CD9 Exosome (EV) Capture Kit - 0.5 ml 0.5 mL size > 10 rxn (50 uL beads per 200 µL sample)
$375.00
AR100094 CD9 Exosome (EV) Capture Kit - 4 x 0.5 ml 4x0.5 mL size > 40 rxn (50 uL beads per 200 µL sample
$1,125.00
AR100095S CD81 Exosome (EV) Capture Kit - 0.5 ml 0.5 mL size > 10 rxn (50 uL beads per 200 µL sample)
$445.00
AR100095 CD81 Exosome (EV) Capture Kit - 4 x 0.5 ml 4x0.5 mL size > 40 rxn (50 uL beads per 200 µL sample
$1,335.00

SKU Name Price Size Cart
AR100094S CD9 Exosome (EV) Capture Kit 0.5 ml
AR100094 CD9 Exosome (EV) Capture Kit 4 x 0.5 ml
AR100095S CD81 Exosome (EV) Capture Kit 0.5 ml
AR100095 CD81 Exosome (EV) Capture Kit 4 x 0.5 ml

COMING SOON

Expanding EV Target Isolation Beyond Tetraspanins

Research Interest Target
Tumor-specific EV EpCAM
Neuron-specific EV NCAM1, L1CAM

Why Choose OriGene's Immunocapture Beads for EV/Exsome Isolation?

Superior Capture Performance

Superior Capture Performance

OriGene EV immunocapture beads use validated high-affinity antibodies coupled to magnetic beads to enrich EV subpopulations from complex samples. This makes the captured EVs cleaner and better suited for downstream assays.
Enhanced EV Marker Enrichment

Enhanced EV Marker Enrichment

Stronger recovery of EV-associated markers in captured fraction, supporting high-quaity enrichment than competitor kits.
Minimum Carryover Protein

Minimum Carryover Protein

Reduced albumin and lipoprotein contamination helps improve the reliability of sensitive downstream workflows such as biomarker detection and functional EV analysis.

Simple Workflow for Efficient Targeted EV Isolation

ev-capture-beads-protocol

Product Resources

Need Help Getting Started?

Contact our technical support team for protocol guidance, compatibility questions, or to request a bulk or custom quote.

Email: support@origene.com

Phone: 1-888-267-4436

Live Chat: Available Mon–Fri 9 AM–5 PM EST

OriGene Complete EV/Exosome Research Solutions

From isolation to functional analysis - everything you need to accelerate your exosome research.

Isolation

Isolation

  • EV Isolation Reagent (Precipitation)
  • Immunocapture Kits (CD9, CD81)
Detection

Detection

  • EV Marker Antibodies
  • Recombinant Proteins
  • Exosome ELISA Kits
Cargo Analysis

Cargo Analysis

  • miRNA qPCR Detection
  • Disease-specific Biomarker Antibodies
Functional Analysis

Functional Analysis

  • GFP-Tagged EV Markers
  • miRNA Target Validation Vectors