EV Solutions
from isolation to
clinical insight

High-quality tools for EV isolation, detection, and characterization.

OriGene offers a comprehensive range of extracellular vesicle research solutions, providing scientists with high-quality tools for EV isolation, detection, and characterization. Supporting applications from cancer research to biomarker discovery and translational studies, our portfolio helps researchers advance scientific understanding and generate meaningful clinical insights.

Hero Image

The portfolio at a glance

Two stages. One integrated workflow.

Isolation / Enrichment

Enrich high-quality EVs

Validated across multiple sample types — choose your method based on sample input and downstream application.

  • ✓ MagExo™ — total EV from serum/plasma for multi-omics & clinical utilities
  • ✓ Precipitation — fast total EV recovery from cell culture media
  • ✓ Immunocapture — marker-specific EV subpopulation enrichment
Characterization

Profile markers & cargo

Four validated tool families to confirm EV identity, quantify subpopulations, and study functional cargo.

  • ✓ Validated antibodies — surface markers & disease targets
  • ✓ ELISA kits — quantify EV subpopulations from biofluids
  • ✓ miRNA toolkits — expression profiling & target validation
  • ✓ Reporter clones & cell lines — visualize EV biogenesis (coming soon!)
02
Characterization

Profile markers & cargo

Four validated tool families to confirm EV identity, quantify subpopulations, and study functional cargo.

  • ✓ Validated antibodies — surface markers & disease targets
  • ✓ ELISA kits — quantify EV subpopulations from biofluids
  • ✓ miRNA toolkits — expression profiling & target validation
  • ✓ Reporter clones & cell lines — visualize EV biogenesis (coming soon!)

Stage 01 · Isolation

Recover EVs your way — no ultracentrifuge required

From total-EV recovery to targeted subpopulation enrichment, pick the method that fits your sample and your downstream assay.

Magnetic Bead · Total EV

MagExo™ EV Isolation Kit

Total EV isolation directly from serum and plasma, engineered for downstream EV multi-omics. Delivers clean, intact vesicles ready for proteomics, RNA/miRNA, and LC/MS workflows.

Serum · Plasma Multi-omics Tested for Clinical Utility
Proteomic Depth in Isolated EVs chart

Polymer Precipitation

EV Isolation Reagent

A powerful alternative to ultracentrifugation and chromatography. Recovers more EVs than ultracentrifugation from cell culture media with a simple mix → incubate → resuspend protocol.

Total EVs Cell culture media < 2 hr No special equipment
Particles per mL chart

Magnetic Immunocapture

EV/Exosome Immunocapture Kits

High-affinity antibodies on magnetic beads enrich specific EV subpopulations with >90% capture efficiency and low protein carryover — cleaner preps for sensitive downstream assays.

CD9 · AR100094 CD81 · AR100095 EV Subpopulations
Capture efficiency chart
 

Magnetic Bead · Total EV

MagExo™ EV Isolation Kit

Total EV isolation directly from serum and plasma, engineered for downstream EV multi-omics. Delivers clean, intact vesicles ready for proteomics, RNA/miRNA, and LC/MS workflows.

Serum · Plasma Multi-omics LC/MS-ready
Proteomic Depth in Isolated EVs chart placeholder
 

Polymer Precipitation

EV Isolation Reagent

A powerful alternative to ultracentrifugation and chromatography. Recovers more EVs than ultracentrifugation from cell culture media with a simple mix → incubate → resuspend protocol.

Total EVs Cell culture media < 2 hr No special equipment
Particles per mL chart placeholder
 

Magnetic Immunocapture

EV/Exosome Immunocapture Kits

High-affinity antibodies on magnetic beads enrich specific EV subpopulations with >90% capture efficiency and low protein carryover — cleaner preps for sensitive downstream assays.

CD9 · AR100094 CD81 · AR100095 EV Subpopulations
Capture efficiency chart placeholder

Stage 02 · Characterization

Profile markers & cargo

After enrichment, confirm EV identity, measure subpopulation abundance, and study functional cargo with four validated tool families — all designed to work with OriGene isolation products.

Validated EV Antibodies

Antibodies validated for EV surface markers (CD9, CD63, CD81) and disease-associated cargo proteins — enabling identity confirmation and target-specific profiling across oncology, neurology, and immunology.

EV markers Disease targets WB · Flow · IF

EV ELISA Kits

Quantify CD9+ and CD81+ EV subpopulations directly from native biofluids — no prior isolation required.

CD9+ · EA200081 CD81+ · EA200082 NCAM1+ & L1CAM+ soon

miRNA Toolkits

A complete miRNA analysis toolkit for EV cargo studies — sensitive qPCR detection assays for expression profiling and 3'UTR reporter vectors for functional miRNA target validation.

qPCR detection Target validation miRNA profiling

Reporter Clones & Cell Lines

Fluorescently tagged EV marker constructs and stable reporter cell lines for direct visualization of EV biogenesis, secretion, and cellular uptake — for mechanistic studies in vitro and in vivo.

GFP fusion Stable cell lines in vitro · in vivo
awesomeicons/solid/draw-polygon

Validated EV Antibodies

Antibodies validated for EV surface markers (CD9, CD63, CD81) and disease-associated cargo proteins — enabling identity confirmation and target-specific profiling across oncology, neurology, and immunology.

EV markers Disease targets WB · Flow · IF
Browse EV antibodies
awesomeicons/regular/calendar-alt

EV ELISA Kits

Quantify CD9+ and CD81+ EV subpopulations directly from native biofluids — no prior isolation required. Paired recombinant protein standards support custom ELISA development and inter-assay standardization.

CD9+ · EA200081 CD81+ · EA200082 NCAM1+ & L1CAM+ soon
Browse EV ELISA Kits
awesomeicons/regular/dot-circle

miRNA Toolkits

A complete miRNA analysis toolkit for EV cargo studies — sensitive qPCR detection assays for expression profiling and 3'UTR reporter vectors for functional miRNA target validation.

qPCR detection Target validation miRNA profiling
Browse miRNA toolkits
Coming Soon
awesomeicons/solid/sun

Reporter Clones & Cell Lines

Fluorescently tagged EV marker constructs and stable reporter cell lines for direct visualization of EV biogenesis, secretion, and cellular uptake — for mechanistic studies in vitro and in vivo.

GFP fusion Stable cell lines in vitro · in vivo

Method selector

Match your sample to the right isolation method

Choose based on your starting material, application, and downstream workflow.

Criteria MagExo™ ★ EV Isolation Reagent Immunocapture Kits
Best for Clinical biofluids · assay development High-yield total EVs (cell culture) Targeted EV subpopulations
Validated sample types Human serum, plasma Cell culture media Biofluids & cell culture media
EV population recovered Total EVs, omics-grade Total EVs Marker-specific (CD9+, CD81+)
Equipment needed Magnetic stand None — bench protocol Magnetic stand
Downstream applications Proteomics · RNA · LC-MS · assay dev WB, ELISA, molecular profiling Biomarker assays, clean preps
Clinical suitability Clinical biomarker & IVD research Research use Research use
  Explore MagExo™ → Learn more → Learn more →

Ready to start your EV project?

Our technical team can help you select the right isolation method, confirm sample compatibility, scope an assay development workflow, or arrange a bulk or custom order.

Talk to our team

Ready to start your EV project?

Our technical team can help you select the right isolation method, confirm sample compatibility, scope an assay development workflow, or arrange a bulk or custom order.

Tell us about your project

Thanks — your inquiry has been noted. Our technical team typically responds within 1–2 business days.
Talk to our team

Ready to start your EV project?

Our technical team can help you select the right isolation method, confirm sample compatibility, scope an assay development workflow, or arrange a bulk or custom order.

Mon–Fri, 9 AM–5 PM EST

Our technical team typically responds within 1–2 business days.

Talk to our team

Ready to start your EV project?

Our technical team can help you select the right isolation method, confirm sample compatibility, scope an assay development workflow, or arrange a bulk or custom order.