Transfection Reagents
High-efficiency delivery for every cell type and payload
High-efficiency, low-toxicity reagents for plasmid DNA, mRNA, siRNA and RNP delivery — from routine cell-line work to the hardest-to-transfect primary cells. Now expanded with next-generation OmniTran™ formulation and rapid-dissolving QuickDissolve PEI™.
Reagent formats in this line
Efficiency, top-performing SKUs
Cell lines validated
Additions to the catalog
Reagent Selection Guide
Not sure where to start? Match your application to the recommended reagent family below.
Primary & Hard-to-Transfect Cells
Coacervate-based protein platform, no electroporation required.
mRNA & In Vivo Applications
Instrument-free lipid nanoparticle formation in under a minute.
Standard & HEK293 Cell Lines
Established, economical workhorse reagents for routine DNA delivery.
High-Titer Packaging
Simple protocol, affordable pricing for large-scale prep.
Transient Transfection at Scale
Polymer-based transfection for suspension and adherent packaging cell lines.
Featured Products
Our top-performing platforms, plus the newest additions to the catalog.
ProteanFect TuffCell Transfection Kit
Non-viral, non-electroporation delivery built on engineered mammalian protein coacervate technology for plasmid DNA, mRNA, siRNA, and CRISPR RNP in primary and difficult-to-transfect cells.
ProteanFect™ CRISPR RNP Transfection Kit
Engineered mammalian coacervate proteins deliver Cas9 protein–sgRNA ribonucleoprotein (RNP) complexes directly into primary and hard-to-transfect cells for gene editing — no electroporation required.
EZ-LNP RNA Transfection Kit
Instrument-free lipid nanoparticle formation, mix and go in under one minute, for both in vitro and in vivo RNA delivery applications.
OmniTran™ Transfection Reagent
Lipofectamine™ 3000 alternative
OmniTran™ is an advanced polymeric transfection reagent designed for high-efficiency, low-toxicity delivery of DNA, siRNA, miRNA, mRNA, and ASO. Its degradation-resistant delivery mechanism protects nucleic acid cargo in transit, with performance validated across standard cell lines (293T, HeLa, MCF7, HepG2, A549, NIH3T3, RAW264.7, HCT116) and primary cells.
QuickDissolve PEI™
MW 40,000 cationic polymer
QuickDissolve PEI™ is a highly charged cationic polymer (MW 40,000) that readily binds nucleic acids for transient transfection, offering low cytotoxicity and high transfection and expression efficiency in cell lines including HEK293 and CHO.
Why Researchers Choose This Line
From coacervate proteins to lipid nanoparticles to cationic polymers, our portfolio covers every delivery mechanism.
Application-Matched Chemistry
200+ Cell Lines Validated
Scales From Bench to Production
Continuously Expanding Portfolio
Not sure which reagent fits your experiment?
Chat with our product specialists or the OriGene AI assistant for a recommendation based on your cell type, payload, and scale.
