shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme American Journal of Cancer Research, 2023 Jun shRNA TR30021
A disintegrin and metalloprotease 12 contributes to colorectal cancer metastasis by regulating epithelial-mesenchymal transition International Journal of Oncology, 2023 Apr shRNA TR30021
An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma Nature Communications, 2023 Apr shRNA TR30021
A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling The EMBO Journal, 2023 Feb shRNA TR30015
Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth. Oncology reports, 2023 Feb shRNA TR30021
In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma Nature Communications, 2023 Jan shRNA TR30012
Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform. Biochemical and biophysical research communications, 2023 Jan shRNA TR30015
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin International Journal of Oncology, 2023 Jan shRNA TR30021
A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration Developmental cell, 2023 Jan shRNA TR30021
Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research, 2022 Nov shRNA TR30021
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia JCI Insight, 2022 Nov shRNA TR30021
Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer Scientific Reports, 2022 Nov shRNA TR30021
Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity Journal for Immunotherapy of Cancer, 2022 Nov shRNA TR30021
The TLK1–MK5 Axis Regulates Motility, Invasion, and Metastasis of Prostate Cancer Cells Cancers, 2022 Nov shRNA TR30021
The STIM1/2-Regulated Calcium Homeostasis Is Impaired in Hippocampal Neurons of the 5xFAD Mouse Model of Alzheimer’s Disease International Journal of Molecular Sciences, 2022 Nov shRNA TR30021
Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS biology, 2022 Sep shRNA TR30012
Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS biology, 2022 Sep shRNA TR30013
BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease International Journal of Molecular Sciences, 2022 Sep shRNA TR30013
DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting Cell reports, 2022 Sep shRNA TR30021
The role of FYCO1-dependent autophagy in lens fiber cell differentiation. Autophagy, 2022 Aug shRNA TR30021
Cadherin‐3 is a novel oncogenic biomarker with prognostic value in glioblastoma Molecular Oncology, 2022 Jun shRNA TR30021
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus eLife, 2022 Apr shRNA TR30021
Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer Cancers, 2022 Feb shRNA TR30021
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR Methods in molecular biology (Clifton, N.J.), 2021 May shRNA TR30013
Attenuation of MAMLD1 Expression Suppresses the Growth and Migratory Properties of Gonadotroph Pituitary Adenomas. Pathology oncology research : POR, 2021 Mar shRNA TR30021
Usp9X Controls Ankyrin-repeat Domain Protein Homeostasis during Dendritic Spine Development Neuron, 2021 Feb shRNA TR30015
The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo The Journal of Physiology, 2020 Dec shRNA TR30021
Molecular Motor KIF3B Acts as a Key Regulator of Dendritic Architecture in Cortical Neurons Frontiers in Cellular Neuroscience, 2020 Oct shRNA TR30021
Intratumoral IFN-α gene delivery reduces tumor-infiltrating regulatory T cells through the downregulation of tumor CCL17 expression. Cancer gene therapy, 2020 Jul shRNA TR30003
Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD + Recycling Cell metabolism, 2020 Apr shRNA TR30012
Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain The Journal of Cell Biology, 2020 Feb shRNA TR30012
Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation. Cell reports, 2019 Dec shRNA TR30003
Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56 Oncogenesis, 2019 Apr shRNA TR30013
Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas Oncotarget, 2018 Dec shRNA TR30012
Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single Step Transformation by KRAS Mutations Cancer cell, 2018 Sep shRNA TR30012
Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma. Biology of the cell, 2018 Jul shRNA TR30021
Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science (New York, N.Y.), 2018 Jan shRNA TR30021
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery eLife, 2017 Dec shRNA TR30012
The role and clinical significance of the CXCL17-CXCR8 (GPR35) axis in breast cancer. Biochemical and biophysical research communications, 2017 Oct shRNA TR30021
A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. Oncogene, 2017 Sep shRNA TR30012
Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle PLoS ONE, 2016 Sep shRNA TR30013
Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle PLoS ONE, 2016 Sep shRNA TR30007
Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway. The American journal of pathology, 2016 Sep shRNA TR30003
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype Nat. Immunol., 2016 Sep shRNA TR30012
Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer Clin. Cancer Res., 2016 Sep shRNA TR30015
Displacement correlations between a single mesenchymal-like cell and its nucleus effectively link subcellular activities and motility in cell migration analysis Sci Rep, 2016 Sep shRNA TR30015
Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease Mol. Psychiatry, 2016 Sep shRNA TR30021
Platelet integrin a6ß1 controls lung metastasis through direct binding to cancer cell-derived ADAM9 JCI Insight, 2016 Sep shRNA TR30021
Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop Oncotarget, 2016 Aug shRNA TR30021
Loss of Trefoil Factor 2 From Pancreatic Duct Glands Promotes Formation of Intraductal Papillary Mucinous Neoplasms in Mice Gastroenterology, 2016 Aug shRNA TR30007