pCMV6-Entry Mammalian Expression Vector

Name: pCMV6-Entry Mammalian Expression Vector
SKU: PS100001

CAT#: PS100001

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pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug

Product Datasheet for 'PS100001'

Cited in 527 publications.

USD 570.00

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Product Data
C-Tag	Myc-DDK
E. coli Selection	Kanamycin
Cell Selection	Neomycin
Features	ORFs cloned in this vector will be expressed in mammalian cellsas a tagged protein with the C-terminal Myc-DDK tags. (DDK is the same as FLAG® which is a registered trademark of Sigma Aldrich). Such clones are the best for detection and purification of the transgene using anti-Myc or anti-DDK antibodies. Serve as the entry vector in the PrecisionShuttle system to transfer the ORF sequence into any destination vectors for other tagging options or other expression platforms. Download full vector sequence
Schematic of the multiple cloning sites

Citations (527)

The use of this Vectors has been cited in the following citations:
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome ,Béziat, V;Tavernier, SJ;Chen, YH;Ma, CS;Materna, M;Laurence, A;Staal, J;Aschenbrenner, D;Roels, L;Worley, L;Claes, K;Gartner, L;Kohn, LA;De Bruyne, M;Schmitz-Abe, K;Charbonnier, LM;Keles, S;Nammour, J;Vladikine, N;Maglorius Renkilaraj, MRL;Seeleuthner, Y;Migaud, M;Rosain, J;Jeljeli, M;Boisson, B;Van Braeckel, E;Rosenfeld, JA;Dai, H;Burrage, LC;Murdock, DR;Lambrecht, BN;Avettand-Fenoel, V;Vogel, TP;, ;Esther, CR;Haskologlu, S;Dogu, F;Ciznar, P;Boutboul, D;Ouachée-Chardin, M;Amourette, J;Lebras, MN;Gauvain, C;Tcherakian, C;Ikinciogullari, A;Beyaert, R;Abel, L;Milner, JD;Grimbacher, B;Couderc, LJ;Butte, MJ;Freeman, AF;Catherinot, É;Fieschi, C;Chatila, TA;Tangye, SG;Uhlig, HH;Haerynck, F;Casanova, JL;Puel, A;, J. Exp. Med. 2020 ,PubMed ID 32207811 [pCMV6-Entry]
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice ,De Jesus, DF;Orime, K;Kaminska, D;Kimura, T;Basile, G;Wang, CH;Haertle, L;Riemens, R;Brown, NK;Hu, J;Männistö, V;Silva, AM;Dirice, E;Tseng, YH;Haaf, T;Pihlajamäki, J;Kulkarni, RN;, J. Clin. Invest. 2020 ,PubMed ID 32250344 [pCMV6-Entry]
Oncogenic ALK\n F1174L\n drives tumorigenesis in cutaneous squamous cell carcinoma ,Gualandi, M;Iorio, M;Engeler, O;Serra-Roma, A;Gasparre, G;Schulte, JH;Hohl, D;Shakhova, O;, Life Sci Alliance 2020 ,PubMed ID 32312912 [pCMV6-Entry]
MicroRNA-4290 suppresses PDK1-mediated glycolysis to enhance the sensitivity of gastric cancer cell to cisplatin ,Qian, Y;Wu, X;Wang, H;Hou, G;Han, X;Song, W;, Braz. J. Med. Biol. Res. 2020 ,PubMed ID 32321153 [pCMV6-Entry]
Phillygenin, a MELK Inhibitor, Inhibits Cell Survival and Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells ,Li, H;Chen, M;Yang, Z;Wang, Q;Wang, J;Jin, D;Yang, X;Chen, F;Zhou, X;Luo, K;, Onco Targets Ther 2020 ,PubMed ID 32308417 [pCMV6-Entry]
YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators ,Fei, Q;Zou, Z;Roundtree, IA;Sun, HL;He, C;, PLoS Biol. 2020 ,PubMed ID 32267835 [pCMV6-Entry]
Ano6 disruption impairs acinar cell regulatory volume decrease and protein secretion in murine submandibular salivary glands ,Munemasa, T;Gao, X;Melvin, JE;Mukaibo, T;, J. Cell. Physiol. 2020 ,PubMed ID 32329061 [pCMV6-Entry]
Downregulation of the Ubiquitin-E3 Ligase RNF123 Promotes Upregulation of the NF-κB1 Target SerpinE1 in Aggressive Glioblastoma Tumors ,Wang, X;Bustos, MA;Zhang, X;Ramos, RI;Tan, C;Iida, Y;Chang, SC;Salomon, MP;Tran, K;Gentry, R;Kravtsova-Ivantsiv, Y;Kelly, DF;Mills, GB;Ciechanover, A;Mao, Y;Hoon, DSB;, Cancers (Basel) 2020 ,PubMed ID 32349217 [pCMV6-Entry]
Long non-coding RNA H19 regulates proliferation and Doxorubicin resistance in MCF-7 cells by targeting PARP1 ,Wang, Y;Zhou, P;Li, P;Yang, F;Gao, X;, Bioengineered 2020 ,PubMed ID 32345117 [pCMV6-Entry]
5-methylcytosine RNA modifications promote retrovirus replication in an ALYREF reader protein-dependent manner ,Eckwahl, M;Xu, R;Michalkiewicz, J;Zhang, W;Patel, P;Cai, Z;Pan, T;, J. Virol. 2020 ,PubMed ID 32321818 [pCMV6-Entry]
Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition ,Maning, J;McCrink, KA;Pollard, CM;Desimine, VL;Ghandour, J;Perez, A;Cora, N;Ferraino, KE;Parker, BM;Brill, AR;Aukszi, B;Lymperopoulos, A;, Int J Mol Sci 2020 ,PubMed ID 32326036 [pCMV6-Entry]
Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression ,Huang, TT;Tseng, LM;Chen, JL;Chu, PY;Lee, CH;Huang, CT;Wang, WL;Lau, KY;Tseng, MF;Chang, YY;Chiang, TY;Ueng, YF;Lee, HC;Dai, MS;Liu, CY;, EBioMedicine 2020 ,PubMed ID 32268268 [pCMV6-Entry]
Endogenous thrombopoietin promotes non‐small‐cell lung carcinoma cell proliferation and migration by regulating EGFR signalling ,Zou, Z;Fan, X;Liu, Y;Sun, Y;Zhang, X;Sun, G;Li, X;Xu, S;, J Cell Mol Med 2020 ,PubMed ID 32337844 [pCMV6-Entry]
Comprehensive Molecular Profiles of Functionally Effective Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles in Immunomodulation ,Kim, H;Lee, M;Bae, E;Ryu, J;Kaur, G;Kim, H;Kim, J;Barreda, H;Jung, S;Choi, J;Shigemoto-Kuroda, T;Oh, J;Lee, R;, Molecular Therapy 2020 ,PubMed ID 32380062 [pCMV6-Entry]
Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs ,Zhang, M;Haughey, M;Wang, NY;Blease, K;Kapoun, AM;Couto, S;Belka, I;Hoey, T;Groza, M;Hartke, J;Bennett, B;Cain, J;Gurney, A;Benish, B;Castiglioni, P;Drew, C;Lachowicz, J;Carayannopoulos, L;Nathan, SD;Distler, J;Brenner, DA;Hariharan, K;Cho, H;Xie, W;, PLoS ONE 2020 ,PubMed ID 32160239 [pCMV6-Entry]
Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP ,Dema, A;Faust, D;Lazarow, K;Wippich, M;Neuenschwander, M;Zühlke, K;Geelhaar, A;Pallien, T;Hallscheidt, E;Eichhorst, J;Wiesner, B;Černecká, H;Popp, O;Mertins, P;Dittmar, G;von Kries, JP;Klussmann, E;, Cells 2020 ,PubMed ID 32164329 [pCMV6-Entry]
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis ,Zheng, YW;Li, ZH;Lei, L;Liu, CC;Wang, Z;Fei, LR;Yang, MQ;Huang, WJ;Xu, HT;, Front Oncol 2020 ,PubMed ID 32195172 [pCMV6-Entry]
Acid/bile exposure triggers TRAIL-mediated apoptosis in esophageal cancer cells by suppressing the decoy receptors and c-FLIPR ,Meng, X;Chang, Z;Che, N;Wu, J;Dang, T;Chai, J;, The International Journal of Biochemistry & Cell Biology 2020 ,PubMed ID 32135301 [pCMV6-Entry]
RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process ,Ke, Y;Guo, W;Huang, S;Li, Y;Guo, Y;Liu, X;Jin, Y;Ma, H;, Life Sci. 2020 ,PubMed ID 32209426 [pCMV6-Entry]
PRDX4 overexpression is associated with poor prognosis in gastric cancer ,Park, S;Lee, Y;Park, J;Kim, T;Hong, S;Jung, E;Ju, Y;Jeong, C;Park, H;Ko, G;Song, D;Park, M;Yoo, J;Jeong, S;, Oncol Lett 2020 ,PubMed ID 32269626 [pCMV6-Entry]
The JAM-B/c-src/MMP9 pathway is associated with progression and regulates the invasion of pancreatic cancer ,Zhang, W;He, R;Chen, S;Zhang, L;Cao, G;Yang, W;Li, J;, J Cancer 2020 ,PubMed ID 32231730 [pCMV6-Entry]
CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis ,Dobson-Stone, C;Hallupp, M;Shahheydari, H;Ragagnin, AMG;Chatterton, Z;Carew-Jones, F;Shepherd, CE;Stefen, H;Paric, E;Fath, T;Thompson, EM;Blumbergs, P;Short, CL;Field, CD;Panegyres, PK;Hecker, J;Nicholson, G;Shaw, AD;Fullerton, JM;Luty, AA;Schofield, PR;Brooks, WS;Rajan, N;Bennett, MF;Bahlo, M;Landers, JE;Piguet, O;Hodges, JR;Halliday, GM;Topp, SD;Smith, BN;Shaw, CE;McCann, E;Fifita, JA;Williams, KL;Atkin, JD;Blair, IP;Kwok, JB;, Brain 2020 ,PubMed ID 32185393 [pCMV6-Entry]
Hepatocyte nuclear factor 4α negatively regulates connective tissue growth factor during liver regeneration ,Zhou, J;Sun, X;Yang, L;Wang, L;Ran, G;Wang, J;Cao, Q;Wu, L;Bryant, A;Ling, C;Pi, L;, FASEB J. 2020 ,PubMed ID 32057145 [pCMV6-Entry]
Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells ,Morillas-Becerril, L;Peta, E;Gabrielli, L;Russo, V;Lubian, E;Nodari, L;Ferlin, MG;Scrimin, P;Palù, G;Barzon, L;Castagliuolo, I;Mancin, F;Trevisan, M;, Nanomaterials (Basel) 2020 ,PubMed ID 32050605 [pCMV6-Entry]
PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling ,Siu, MKY;Jiang, YX;Wang, JJ;Leung, THY;Ngu, SF;Cheung, ANY;Ngan, HYS;Chan, KKL;, Oncogenesis 2020 ,PubMed ID 32071289 [pCMV6-Entry]
Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage ,Deng, S;Essandoh, K;Wang, X;Li, Y;Huang, W;Chen, J;Peng, J;Jiang, DS;Mu, X;Wang, C;Peng, T;Guan, JL;Wang, Y;Jegga, A;Huang, K;Fan, GC;, Redox Biol 2020 ,PubMed ID 32057709 [pCMV6-Entry]
A novel heterozygous STAT5B variant in a patient with short stature and partial growth hormone insensitivity (GHI) ,Ramírez, L;Sanguineti, N;Scaglia, P;Keselman, A;Ballerini, M;Karabatas, L;Landi, E;Castro, J;Domené, S;Pennisi, P;Jasper, H;Rey, R;Vázquez, M;Domené, H;Bergadá, I;Gutiérrez, M;, Growth Hormone & IGF Research 2020 ,PubMed ID 31902742 [pCMV6-Entry]
ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagy ,Meng, J;Liu, K;Shao, Y;Feng, X;Ji, Z;Chang, B;Wang, Y;Xu, L;Yang, G;, Cell Death Dis 2020 ,PubMed ID 32080166 [pCMV6-Entry]
A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2 ,Leung, MH;Tsoi, H;Gong, C;Man, EP;Zona, S;Yao, S;Lam, EW;Khoo, US;, Cancers (Basel) 2020 ,PubMed ID 32110852 [pCMV6-Entry]
miR-23a-3p/SIX1 regulates glucose uptake and proliferation through GLUT3 in head and neck squamous cell carcinomas ,Wang, H;Xue, W;Ouyang, W;Jiang, X;Jiang, X;, J. Cancer 2020 ,PubMed ID 32201523 [pCMV6-Entry]
Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma ,Tee, AE;Ciampa, OC;Wong, M;Fletcher, JI;Kamili, A;Chen, J;Ho, N;Sun, Y;Carter, DR;Cheung, BB;Marshall, GM;Liu, PY;Liu, T;, Int. J. Cancer 2020 ,PubMed ID 32086952 [pCMV6-Entry]
A Comprehensive Analysis of FUT8 Overexpressing Prostate Cancer Cells Reveals the Role of EGFR in Castration Resistance ,Höti, N;Lih, TS;Pan, J;Zhou, Y;Yang, G;Deng, A;Chen, L;Dong, M;Yang, RB;Tu, CF;Haffner, MC;Kay Li, Q;Zhang, H;, Cancers (Basel) 2020 ,PubMed ID 32085441 [pCMV6-Entry]
MiR-1285-5p/TMEM194A axis affects cell proliferation in breast cancer ,Hironaka-Mitsuhashi, A;Otsuka, K;Gailhouste, L;Sanchez Calle, A;Kumazaki, M;Yamamoto, Y;Fujiwara, Y;Ochiya, T;, Cancer Sci. 2020 ,PubMed ID 31854049 [pCMV6-Entry]
DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1 ,Ziogas, A;Maekawa, T;Wiessner, JR;Le, TT;Sprott, D;Troullinaki, M;Neuwirth, A;Anastasopoulou, V;Grossklaus, S;Chung, KJ;Sperandio, M;Chavakis, T;Hajishengallis, G;Alexaki, VI;, J. Immunol. 2020 ,PubMed ID 31980574 [pCMV6-Entry]
The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway ,Rigby, MJ;Ding, Y;Farrugia, MA;Feig, M;Cortese, GP;Mitchell, H;Burger, C;Puglielli, L;, J. Neurochem. 2020 ,PubMed ID 31945187 [pCMV6-Entry]
Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seq ,Vazquez, SE;Ferre, EMN;Scheel, DW;Sunshine, S;, bioRxiv 2020 [pCMV6-Entry]
Trefoil factor 1 (TFF1) is a potential prognostic biomarker with functional significance in breast cancers ,Yi, J;Ren, L;Li, D;Wu, J;Li, W;Du, G;Wang, J;, Biomed. Pharmacother. 2020 ,PubMed ID 31986408 [pCMV6-Entry]
Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells ,Kahancová, A;Sklenář, F;Ježek, P;Dlasková, A;, Sci Rep 2020 ,PubMed ID 32005857 [pCMV6-Entry]
Proprotein convertase 7 (PCSK7) reduces apoA-V levels ,Ashraf, Y;Duval, S;Sachan, V;Essalmani, R;Susan-Resiga, D;Roubtsova, A;Hamelin, J;Gerhardy, S;Kirchhofer, D;Tagliabracci, VS;Prat, A;Kiss, RS;Seidah, NG;, FEBS J. 2020 ,PubMed ID 31945259 [pCMV6-Entry]
Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer ,Cheung, EC;DeNicola, GM;Nixon, C;Blyth, K;Labuschagne, CF;Tuveson, DA;Vousden, KH;, Cancer Cell 2020 ,PubMed ID 31983610 [pCMV6-Entry]
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease ,Lalaoui, N;Boyden, SE;Oda, H;Wood, GM;Stone, DL;Chau, D;Liu, L;Stoffels, M;Kratina, T;Lawlor, KE;Zaal, KJM;Hoffmann, PM;Etemadi, N;Shield-Artin, K;Biben, C;Tsai, WL;Blake, MD;Kuehn, HS;Yang, D;Anderton, H;Silke, N;Wachsmuth, L;Zheng, L;Moura, NS;Beck, DB;Gutierrez-Cruz, G;Ombrello, AK;Pinto-Patarroyo, GP;Kueh, AJ;Herold, MJ;Hall, C;Wang, H;Chae, JJ;Dmitrieva, NI;McKenzie, M;Light, A;Barham, BK;Jones, A;Romeo, TM;Zhou, Q;Aksentijevich, I;Mullikin, JC;Gross, AJ;Shum, AK;Hawkins, ED;Masters, SL;Lenardo, MJ;Boehm, M;Rosenzweig, SD;Pasparakis, M;Voss, AK;Gadina, M;Kastner, DL;Silke, J;, Nature 2020 ,PubMed ID 31827281 [pCMV6-Entry]
Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IV ,Protasoni, M;Pérez-Pérez, R;Lobo-Jarne, T;Harbour, ME;Ding, S;Peñas, A;Diaz, F;Moraes, CT;Fearnley, IM;Zeviani, M;Ugalde, C;Fernández-Vizarra, E;, EMBO J. 2020 ,PubMed ID 31912925 [pCMV6-Entry]
Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice ,Maeda-Smithies, N;Hiller, S;Dong, S;Kim, HS;Bennett, BJ;Kayashima, Y;, Mamm. Genome 2020 ,PubMed ID 31912264 [pCMV6-Entry]
Genistein Represses HOTAIR/Chromatin Remodeling Pathways to Suppress Kidney Cancer ,Imai-Sumida, M;Dasgupta, P;Kulkarni, P;Shiina, M;Hashimoto, Y;Shahryari, V;Majid, S;Tanaka, Y;Dahiya, R;Yamamura, S;, Cell. Physiol. Biochem. 2020 ,PubMed ID 31961100 [pCMV6-Entry]
Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma ,Wu, WR;Lin, JT;Pan, CT;Chan, TC;Liu, CL;Wu, WJ;Sheu, JJ;Yeh, BW;Huang, SK;Jhung, JY;Hsiao, MS;Li, CF;Shiue, YL;, Theranostics 2020 ,PubMed ID 31903146 [pCMV6-Entry]
In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits ,Ruan, X;Li, P;Chen, Y;Shi, Y;Pirooznia, M;Seifuddin, F;, researchgate.net 2019 ,PubMed ID 31896749 [pCMV6-Entry]
Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulators ,Ruan, X;Li, P;Ma, Y;Jiang, C;Chen, Y;Shi, Y;Gupta, N;, bioRxiv 2020 [pCMV6-Entry]
Visual arrestin modulates gene expression in the retinal pigment epithelium: Implications for homeostasis in the retina ,Nagaoka, N;Yoshida, T;Cao, K;Iwasaki, Y;Nakahama, KI;Morita, I;Ohno-Matsui, K;, Biochem Biophys Rep 2019 ,PubMed ID 31467992 [pCMV6-Entry]
Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands ,Yang, NY;Mukaibo, T;Gao, X;Kurtz, I;Melvin, JE;, Physiol Rep 2019 ,PubMed ID 31833218 [pCMV6-Entry]
RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma ,Gong, S;Qu, X;Yang, S;Zhou, S;Li, P;Zhang, Q;, Int. J. Mol. Med. 2019 ,PubMed ID 31661124 [pCMV6-Entry]
A Germline Mutation in the C2 Domain of PLCγ2 Associated with Gain-of-Function Expands the Phenotype for PLCG2-Related Diseases ,Novice, T;Kariminia, A;Del Bel, KL;Lu, H;Sharma, M;Lim, CJ;Read, J;Lugt, MV;Hannibal, MC;O'Dwyer, D;Hosler, M;Scharnitz, T;Rizzo, JM;Zacur, J;Priatel, J;Abdossamadi, S;Bohm, A;Junker, A;Turvey, SE;Schultz, KR;Rozmus, J;, J. Clin. Immunol. 2019 ,PubMed ID 31853824 [pCMV6-Entry]
Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3 ,Wang, CY;Xu, Y;Traeger, L;Dogan, DY;Xiao, X;Steinbicker, AU;Babitt, JL;, Blood 2019 ,PubMed ID 31800957 [pCMV6-Entry]
Dazl determines primordial follicle formation through the translational regulation of Tex14 ,Rosario, R;Crichton, JH;Stewart, HL;Childs, AJ;Adams, IR;Anderson, RA;, FASEB J. 2019 ,PubMed ID 31659914 [pCMV6-Entry]
Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy ,Miyajima, T;Melangath, G;Zhu, S;Deshpande, N;Vasanth, S;Mondal, B;Kumar, V;Chen, Y;Price, MO;Price, FW;Rogan, EG;Zahid, M;Jurkunas, UV;, Free Radic. Biol. Med. 2019 ,PubMed ID 31857234 [pCMV6-Entry]
Uev1A promotes breast cancer cell survival and chemoresistance through the AKT-FOXO1-BIM pathway ,Wu, Z;Niu, T;Xiao, W;, Cancer Cell Int. 2019 ,PubMed ID 31827405 [pCMV6-Entry]
MiR-7-5p suppresses tumor metastasis of non-small cell lung cancer by targeting NOVA2 ,Xiao, H;, Cell Mol Biol Lett 2019 ,PubMed ID 31832068 [pCMV6-Entry]
Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases ,Wang, L;Ren, A;Tian, T;Li, N;Cao, X;Zhang, P;Jin, L;Li, Z;Shen, Y;Zhang, B;Finnell, RH;Lei, Y;, Front Neurosci 2019 ,PubMed ID 31849593 [pCMV6-Entry]
17q21. 31 sub-haplotypes underlying H1-associated risk for Parkinson\'s disease and progressive supranuclear palsy converge on altered glial regulation ,Bowles, KR;Pugh, DA;Farrell, K;Han, N;Julia, TCW;, bioRxiv 2019 [pCMV6-Entry]
A male infertility mutation reverts NANOS1 activity from anti-apoptotic to pro-apoptotic by disrupting repression of GADD45A, GADD45B, GADD45G and RHOB genes ,Janecki, DM;Ilaslan, E;Smialek, MJ;Sajek, MP;, bioRxiv 2019 [pCMV6-Entry]
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo ,Bai, L;Zhou, H;Xu, R;Zhao, Y;Chinnaswamy, K;McEachern, D;Chen, J;Yang, CY;Liu, Z;Wang, M;Liu, L;Jiang, H;Wen, B;Kumar, P;Meagher, JL;Sun, D;Stuckey, JA;Wang, S;, Cancer Cell 2019 ,PubMed ID 31715132 [pCMV6-Entry]
Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells ,Sellitto, A;Geles, K;D'Agostino, Y;Conte, M;Alexandrova, E;Rocco, D;Nassa, G;Giurato, G;Tarallo, R;Weisz, A;Rizzo, F;, Cells 2019 ,PubMed ID 31694219 [pCMV6-Entry]
Induction of APOBEC3C Facilitates the Genotoxic Stress-Mediated Cytotoxicity of Artesunate ,Tao, L;Jiang, Z;Xu, M;Xu, T;Liu, Y;, Chem. Res. Toxicol. 2019 ,PubMed ID 31664825 [pCMV6-Entry]
FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53 ,Xu, M;Zhu, J;Liu, S;Wang, C;Shi, Q;Kuang, Y;Fang, X;Hu, X;, Carcinogenesis 2019 ,PubMed ID 31784734 [pCMV6-Entry]
FAM53A Affects Breast Cancer Cell Proliferation, Migration, and Invasion in a p53-Dependent Manner ,Zhang, J;Sun, M;Hao, M;Diao, K;Wang, J;Li, S;Cao, Q;Mi, X;, Front Oncol 2019 ,PubMed ID 31799197 [pCMV6-Entry]
Rsf‑1 regulates malignant melanoma cell viability and chemoresistance via NF‑κB/Bcl‑2 signaling ,He, J;Fu, L;Li, Q;, Mol Med Rep 2019 ,PubMed ID 31485613 [pCMV6-Entry]
Patchouli alcohol activates PXR and suppresses the NF-κB-mediated intestinal inflammatory ,Zhang, G;Liu, M;Song, M;Wang, J;Cai, J;Lin, C;Li, Y;Jin, X;Shen, C;Chen, Z;Cai, D;Zhu, C;Lin, C;Liu, C;, J Ethnopharmacol 2019 ,PubMed ID 31614203 [pCMV6-Entry]
Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta via disruption of STRA6 cascade ,Chen, CH;Ke, LY;Chan, HC;Chu, CS;Lee, AS;Lin, KD;Lee, MY;Hsiao, PJ;Chen, CH;Shin, SJ;, J Diabetes Investig 2019 ,PubMed ID 31597015 [pCMV6-Entry]
SOX17 Inhibits Tumor Metastasis Via Wnt Signaling In Endometrial Cancer ,Zhou, W;Wang, K;Wang, J;Qu, J;Du, G;Zhang, Y;, Onco Targets Ther 2019 ,PubMed ID 31632077 [pCMV6-Entry]
An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis ,Laurin, M;Gomez, NC;Levorse, J;Sendoel, A;Sribour, M;Fuchs, E;, Elife 2019 ,PubMed ID 31556874 [pCMV6-Entry]
miR-122-5p promotes aggression and epithelial-mesenchymal transition in triple-negative breast cancer by suppressing charged multivesicular body protein 3 through mitogen-activated protein kinase signaling ,Wang, Z;Wang, X;, J. Cell. Physiol. 2019 ,PubMed ID 31541468 [pCMV6-Entry]
Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling ,Böhm, AM;Dirckx, N;Tower, RJ;Peredo, N;Vanuytven, S;Theunis, K;Nefyodova, E;Cardoen, R;Lindner, V;Voet, T;Van Hul, M;Maes, C;, Dev. Cell 2019 ,PubMed ID 31543445 [pCMV6-Entry]
Enterovirus A71 capsid protein VP1 increases blood-brain barrier permeability and virus receptor vimentin on the brain endothelial cells ,Wang, W;Sun, J;Wang, N;Sun, Z;Ma, Q;Li, J;Zhang, M;Xu, J;, J. Neurovirol. 2019 ,PubMed ID 31512144 [pCMV6-Entry]
Repurposing cell growth-regulating compounds identifies kenpaullone which ameliorates pathologic pain via normalization of inhibitory neurotransmission ,Yeo, M;Chen, Y;Jiang, C;Chen, G;Lioudyno, M;Zeng, Q;, bioRxiv 2019 [pCMV6-Entry]
Network Analysis of Inflammatory Bowel Disease Reveals PTPN2 As New Monogenic Cause of Intestinal Inflammation ,Parlato, M;Pazmandi, J;Nian, Q;Charbit-Henrion, F;, bioRxiv 2019 [pCMV6-Entry]
Serotonin receptor 4 in mature excitatory hippocampal neurons modulates mood and anxiety ,Karayol, R;Medrihan, L;Warner-Schmidt, JL;Rao, MN;, bioRxiv 2019 [pCMV6-Entry]
Redistribution of EC-SOD resolves bleomycin-induced inflammation via increased apoptosis of recruited alveolar macrophages ,Allawzi, A;McDermott, I;Delaney, C;Nguyen, K;Banimostafa, L;Trumpie, A;Hernandez-Lagunas, L;Riemondy, K;Gillen, A;Hesselberth, J;El Kasmi, K;Sucharov, CC;Janssen, WJ;Stenmark, K;Bowler, R;Nozik-Grayck, E;, FASEB J. 2019 ,PubMed ID 31560857 [pCMV6-Entry]
A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination ,Su, W;Matsumoto, S;Banine, F;Srivastava, T;Dean, J;Foster, S;Pham, P;Hammond, B;Peters, A;Girish, KS;Rangappa, KS;Basappa, ;Jose, J;Hennebold, JD;Murphy, MJ;Bennett-Toomey, J;Back, SA;Sherman, LS;, Glia 2019 ,PubMed ID 31490574 [pCMV6-Entry]
Expression of endoplasmic reticulum mannosyl-oligosaccharide α1, 2-mannosidase regulates tumorigenicity of prostate cancer cells ,Toonstra, C;Wang, X;Hoti, N;Pan, J;Zhang, H;, bioRxiv 2019 [pCMV6-Entry]
P27 Promotes TGF-β-Mediated Pulmonary Fibrosis via Interacting with MTORC2 ,Dai, Y;Li, X;Dong, D;Gu, H;Kong, C;Xu, Z;, Canadian Respiratory Journal 2019 ,PubMed ID 31641391 [pCMV6-Entry]
Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation ,Vella, V;Nicolosi, ML;Giuliano, M;Morrione, A;Malaguarnera, R;Belfiore, A;, Cells 2019 ,PubMed ID 31480557 [pCMV6-Entry]
Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells ,Park, SJ;Kim, H;Kim, SH;Joe, EH;Jou, I;, Acta Neuropathol Commun 2019 ,PubMed ID 31530290 [pCMV6-Entry]
MicroRNA-519c-3p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting BTG3 ,Wang, L;Mo, H;Jiang, Y;Wang, Y;Sun, L;Yao, B;Chen, T;Liu, R;Li, Q;Liu, Q;Yin, G;, Biomed. Pharmacother. 2019 ,PubMed ID 31387005 [pCMV6-Entry]
SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway ,Sun, X;Wang, S;Gai, J;Guan, J;Li, J;Li, Y;Zhao, J;Zhao, C;Fu, L;Li, Q;, Front Oncol 2019 ,PubMed ID 31456942 [pCMV6-Entry]
RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2 ,Yang, YL;Zhang, Y;Li, DD;Zhang, FL;Liu, HY;Liao, XH;Xie, HY;Lu, Q;Zhang, L;Hong, Q;Dong, WJ;Li, DQ;Shao, ZM;, Cell Death Differ. 2019 ,PubMed ID 31406303 [pCMV6-Entry]
Upregulation of Myc promotes the evasion of NK cell‑mediated immunity through suppression of NKG2D ligands in K562 cells ,Lee, YS;Heo, W;Son, CH;Kang, CD;Park, YS;Bae, J;, Mol Med Rep 2019 ,PubMed ID 31432134 [pCMV6-Entry]
Data on the function of CDH17 in pancreatic cancer growth ,Yuan, H;Stenberg, J;Li, G;, Data in Brief 2019 ,PubMed ID 31516924 [pCMV6-Entry]
Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma ,Ursu, S;Majid, S;Garger, C;de Semir, D;Bezrookove, V;Desprez, PY;McAllister, S;Soroceanu, L;Nosrati, M;Yimam, K;Hassoun, A;Osorio, R;Kashani-Sabet, M;Dar, AA;, Oncogenesis 2019 ,PubMed ID 31409772 [pCMV6-Entry]
Exostosin-1 enhances canonical Wnt signaling activity during chondrogenic differentiation ,Wang, X;Cornelis, FMF;Lories, RJ;Monteagudo, S;, Osteoarthr. Cartil. 2019 ,PubMed ID 31330188 [pCMV6-Entry]
ATAD2 expression increases [18F]Fluorodeoxyglucose uptake value in lung adenocarcinoma via AKT-GLUT1/HK2 pathway ,Sun, T;Du, B;Diao, Y;Li, X;Chen, S;Li, Y;, BMB Rep 2019 ,PubMed ID 31186081 [pCMV6-Entry]
HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission ,Pisciottani, A;Biancolillo, L;Ferrara, M;Valente, D;Sardina, F;Monteonofrio, L;Camerini, S;Crescenzi, M;Soddu, S;Rinaldo, C;, Cells 2019 ,PubMed ID 31284535 [pCMV6-Entry]
Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance Induced by Membranous/Cytoplasmic/Nuclear Translocation of Epidermal Growth Factor Receptor ,Rong, X;Liang, Y;Han, Q;Zhao, Y;Jiang, G;Zhang, X;Lin, X;Liu, Y;Zhang, Y;Han, X;Zhang, M;Luo, Y;Li, P;Wei, L;Yan, T;Wang, E;, J Thorac Oncol 2019 ,PubMed ID 31228625 [pCMV6-Entry]
microRNA-548b suppresses aggressive phenotypes of hepatocellular carcinoma by directly targeting high-mobility group box 1 mRNA ,Yun, Z;Meng, F;Jiang, P;Yue, M;Li, S;, CMAR 2019 ,PubMed ID 31417317 [pCMV6-Entry]
Up-Regulated AKR1C2 is correlated with favorable prognosis in thyroid carcinoma ,Jin, YX;Zhou, X;Chen, Y;Jin, W;Wang, Y;Ye, D;Sun, Y;, journal of cancer 2019 ,PubMed ID 31293659 [pCMV6-Entry]
miR-3691-5p promotes hepatocellular carcinoma cell migration and invasion through activating PI3K/Akt signaling by targeting PTEN ,Du, W;Zhang, X;Wan, Z;, Onco Targets Ther 2019 ,PubMed ID 31417285 [pCMV6-Entry]
MicroRNA-582-5p suppresses non-small cell lung cancer cells growth and invasion via downregulating NOTCH1 ,Liu, J;Liu, S;Deng, X;Rao, J;Huang, K;Xu, G;Wang, X;, PLoS ONE 2019 ,PubMed ID 31170211 [pCMV6-Entry]
Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades ,Siu, MKY;Jiang, YX;Wang, JJ;Leung, THY;Han, CY;Tsang, BK;Cheung, ANY;Ngan, HYS;Chan, KKL;, Cancers (Basel) 2019 ,PubMed ID 31212816 [pCMV6-Entry]
Post-translational inhibition of YAP oncogene expression by 4-hydroxynonenal in bladder cancer cells ,Cucci, MA;Compagnone, A;Daga, M;Grattarola, M;Ullio, C;Roetto, A;Palmieri, A;Rosa, AC;Argenziano, M;Cavalli, R;Simile, MM;Pascale, RM;Dianzani, C;Barrera, G;Pizzimenti, S;, Free Radic. Biol. Med. 2019 ,PubMed ID 31207288 [pCMV6-Entry]
miR‑802 inhibits the aggressive behaviors of non‑small cell lung cancer cells by directly targeting FGFR1 ,Zhang, J;Li, J;Li, S;Zhou, C;Qin, Y;Li, X;, Int. J. Oncol. 2019 ,PubMed ID 30942425 [pCMV6-Entry]
MicoRNA-301a Promotes Pancreatic cancer Invasion and Metastasis through the JAK/STAT3 Signaling Pathway by Targeting SOCS5 ,Hu, H;Zhang, Q;Chen, W;Wu, T;Liu, S;Li, X;Luo, B;Zhang, T;Yan, G;Lu, H;Lu, Z;, Carcinogenesis 2019 ,PubMed ID 31233116 [pCMV6-Entry]
Cbl interacts with multiple E2s in vitro and in cells ,Liyasova, MS;Ma, K;Voeller, D;Ryan, PE;Chen, J;Klevit, RE;Lipkowitz, S;, PLoS ONE 2019 ,PubMed ID 31120930 [pCMV6-Entry]
The Protective Effect of Aromatase on NSC-34 Cells with Stably Expressed hSOD1-G93A ,Yan, L;Qi, W;Liu, Y;Zhou, F;Wang, Y;Bai, L;Zhou, X;Sun, C;Nie, X;Duan, S;Ran, J;Chen, J;Ji, Y;Liu, Y;Li, Z;Li, Y;Wang, Q;, Neuroscience 2019 ,PubMed ID 31129201 [pCMV6-Entry]
DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail ,Furuta, M;Kikuchi, H;Shoji, T;Takashima, Y;Kikuchi, E;Kikuchi, J;Kinoshita, I;Dosaka-Akita, H;Sakakibara-Konishi, J;, Cancer Sci. 2019 ,PubMed ID 30874360 [pCMV6-Entry]
Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer ,Shin, YJ;Kim, Y;Wen, X;Cho, NY;Lee, S;Kim, WH;Kang, GH;, Clin Epigenetics 2019 ,PubMed ID 31088544 [PS100001]
Amplification of genomic regions harbouring genes with dose-limiting effects provides selection pressure for acquiring aberrant epigenetic silencing in ovarian cancer ,Bonito, N;Eringyte, I;Masrour, N;Wilhelm-Benartzi, CS;, BioRxiv 2019 [pCMV6-Entry]
IQGAP2 acts as a tumor suppressor in breast cancer and its reduced expression promotes cancer growth and metastasis by MEK/ERK signalling pathways ,Kumar, D;Hassan, MK;Pattanaik, N;Mohapatra, N;, bioRxiv 2019 [pCMV6-Entry]
Comparison of cord blood CD34 + stem cell expansion in coculture with mesenchymal stem cells overexpressing SDF-1 and soluble /membrane isoforms of SCF ,Ajami, M;Soleimani, M;Abroun, S;Atashi, A;, J. Cell. Biochem. 2019 ,PubMed ID 31099108 [pCMV6-Entry]
Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype ,Sharma, P;Reichert, M;Lu, Y;Markello, TC;Adams, DR;Steinbach, PJ;Fuqua, BK;Parisi, X;Kaler, SG;Vulpe, CD;Anderson, GJ;Gahl, WA;Malicdan, MCV;, PLoS Genet. 2019 ,PubMed ID 31125343 [pCMV6-Entry]
Cytokine regulated phosphorylation and activation of TET2 by JAK2 in hematopoiesis ,Jeong, JJ;Gu, X;Nie, J;Sundaravel, S;Liu, H;Kuo, WL;Bhagat, TD;Pradhan, K;Cao, J;Nischal, S;McGraw, KL;Bhattacharyya, S;Bishop, MR;Artz, A;Thirman, MJ;Moliterno, A;Ji, P;Levine, RL;Godley, LA;Steidl, U;Bieker, J;List, AF;Sauntharajah, Y;He, C;Verma, A;Wickrema, A;, Cancer Discov 2019 ,PubMed ID 30944118 [pCMV6-Entry]
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells ,Berdan, CA;Ho, R;Lehtola, HS;To, M;Hu, X;Huffman, TR;Petri, Y;Altobelli, CR;Demeulenaere, SG;Olzmann, JA;Maimone, TJ;Nomura, DK;, Cell Chem Biol 2019 ,PubMed ID 31080076 [pCMV6-Entry]
Transient Receptor Potential Mucolipin-1 Channels in Glioblastoma: Role in Patient's Survival ,Morelli, MB;Amantini, C;Tomassoni, D;Nabissi, M;Arcella, A;Santoni, G;, Cancers (Basel) 2019 ,PubMed ID 31013784 [pCMV6-Entry]
HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy ,Emmons, MF;Faião-Flores, F;Sharma, R;Thapa, R;Messina, JL;Becker, JC;Schadendorf, D;Seto, E;Sondak, VK;Koomen, JM;Chen, YA;Lau, EK;Wan, L;Licht, JD;Smalley, KSM;, Cancer Res. 2019 ,PubMed ID 30987999 [pCMV6-Entry]
Viable and efficient electroporation-based genetic manipulation of unstimulated human T cells ,Aksoy, P;Aksoy, BA;Czech, E;Hammerbacher, J;, bioRxiv 2019 [pCMV6-Entry]
uPAR isoform 2 forms a dimer and induces severe kidney disease in mice ,Wei, C;Li, J;Adair, BD;Zhu, K;Cai, J;Merchant, M;Samelko, B;Liao, Z;Koh, KH;Tardi, NJ;Dande, RR;Liu, S;Ma, J;Dibartolo, S;Hägele, S;Peev, V;Hayek, SS;Cimbaluk, DJ;Tracy, M;Klein, J;Sever, S;Shattil, SJ;Arnaout, MA;Reiser, J;, J. Clin. Invest. 2019 ,PubMed ID 30730305 [pCMV6-Entry]
miR-374a-5p promotes tumor progression by targeting ARRB1 in triple negative breast cancer ,Son, D;Kim, Y;Lim, S;Kang, HG;Kim, DH;Park, JW;Cheong, W;Kong, HK;Han, W;Park, WY;Chun, KH;Park, JH;, Cancer Lett. 2019 ,PubMed ID 31004703 [pCMV6-Entry]
Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix (Matriderm®): Potential Approach for an Immune-Privileged Skin Substitute ,Schlottmann, F;Strauss, S;Hake, K;Vogt, PM;Bucan, V;, Int J Mol Sci 2019 ,PubMed ID 31027326 [pCMV6-Entry]
Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells ,Sak, M;Zumbar, CT;King, PD;Li, X;Mifsud, CS;Usubalieva, A;Anderson, CD;Chesnick, HM;McElroy, JP;Chakravarti, A;Burton, EC;Lehman, NL;, J. Neurooncol. 2019 ,PubMed ID 31011934 [pCMV6-Entry]
Plumbagin inhibits proliferation and induces apoptosis of hepatocellular carcinoma by downregulating the expression of SIVA ,Li, T;Lv, M;Chen, X;Yu, Y;Zang, G;Tang, Z;, Drug Des Devel Ther 2019 ,PubMed ID 31118568 [pCMV6-Entry]
Reciprocal interaction of HOTAIR and SP1 together enhance the ability of Xiaoji decoction and gefitinib to inhibit EP4 expression ,Wu, J;Tang, Q;Ren, X;Zheng, F;He, C;Chai, X;Li, L;Hann, SS;, J Ethnopharmacol 2019 ,PubMed ID 30910577 [pCMV6-Entry]
ERα upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-κB in breast cancer ,Wang, Z;Katsaros, D;Biglia, N;Shen, Y;Loo, L;Yu, X;Lin, H;Fu, Y;Chu, WM;Fei, P;Ni, Y;Jia, W;Deng, X;Qian, B;Yu, H;, Breast Cancer Res. Treat. 2019 ,PubMed ID 30830488 [pCMV6-Entry]
Overactive IGF1/Insulin Receptors and NRASQ61R Mutation Drive Mechanisms of Resistance to Pazopanib and Define Rational Combination Strategies to Treat Synovial Sarcoma ,Lanzi, C;Dal Bo, L;Favini, E;Tortoreto, M;Beretta, GL;Arrighetti, N;Zaffaroni, N;Cassinelli, G;, Cancers (Basel) 2019 ,PubMed ID 30909453 [pCMV6-Entry]
Clinical genome sequencing uncovers potentially targetable truncations and fusions of MAP3K8 in spitzoid and other melanomas ,Newman, S;Fan, L;Pribnow, A;Silkov, A;Rice, SV;Lee, S;Shao, Y;Shaner, B;Mulder, H;Nakitandwe, J;Shurtleff, S;Azzato, EM;Wu, G;Zhou, X;Barnhill, R;Easton, J;Nichols, KE;Ellison, DW;Downing, JR;Pappo, A;Potter, PM;Zhang, J;Bahrami, A;, Nat. Med. 2019 ,PubMed ID 30833747 [pCMV6-Entry]
Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop ,Bagratuni, T;Sklirou, AD;Kastritis, E;Liacos, CI;Spilioti, C;Eleutherakis-Papaiakovou, E;Kanellias, N;Gavriatopoulou, M;Terpos, E;Trougakos, IP;Dimopoulos, MA;, Sci Rep 2019 ,PubMed ID 30824741 [pCMV6-Entry]
An essential role for the Zn2+ transporter ZIP7 in B cell development ,Anzilotti, C;Swan, DJ;Boisson, B;Deobagkar-Lele, M;Oliveira, C;Chabosseau, P;Engelhardt, KR;Xu, X;Chen, R;Alvarez, L;Berlinguer-Palmini, R;Bull, KR;Cawthorne, E;Cribbs, AP;Crockford, TL;Dang, TS;Fearn, A;Fenech, EJ;de Jong, SJ;Lagerholm, BC;Ma, CS;Sims, D;van den Berg, B;Xu, Y;Cant, AJ;Kleiner, G;Leahy, TR;de la Morena, MT;Puck, JM;Shapiro, RS;van der Burg, M;Chapman, JR;Christianson, JC;Davies, B;McGrath, JA;Przyborski, S;Santibanez Koref, M;Tangye, SG;Werner, A;Rutter, GA;Padilla-Parra, S;Casanova, JL;Cornall, RJ;Conley, ME;Hambleton, S;, Nat. Immunol. 2019 ,PubMed ID 30718914 [pCMV6-AC-myc-DDK]
The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer ,Jin, Z;Zhang, G;Liu, Y;He, Y;Yang, C;Du, Y;Gao, F;, Journal of Gastroenterology and Hepatology 2019 ,PubMed ID 30972813 [pCMV6-Entry]
The Rho-family GEF FARP2 is activated by aPKCι to control polarity and tight junction formation ,Elbediwy, A;Zhang, Y;Cobbaut, M;Riou, P;Tan, RS;, J Cell Sci 2019 ,PubMed ID 30872454 [pCMV6-Entry]
N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation ,Wen, Z;Jin, K;Shen, Y;Yang, Z;Li, Y;Wu, B;Tian, L;Shoor, S;Roche, NE;Goronzy, JJ;Weyand, CM;, Nat. Immunol. 2019 ,PubMed ID 30718913 [pCMV6-Entry]
DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53 ,Wudu, M;Ren, H;Hui, L;Jiang, J;Zhang, S;Xu, Y;Wang, Q;Su, H;Jiang, X;Dao, R;Qiu, X;, J. Exp. Clin. Cancer Res. 2019 ,PubMed ID 30755245 [pCMV6-Entry]
Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction ,Brownfoot, FC;Hannan, NJ;Cannon, P;Nguyen, V;Hastie, R;Parry, LJ;Senadheera, S;Tuohey, L;Tong, S;Kaitu'u-Lino, TJ;, EBioMedicine 2019 ,PubMed ID 30824385 [pCMV6-Entry]
Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation ,Zhou, Z;Ni, C;Wu, L;Chen, B;Xu, Y;Zhang, Z;Mu, J;Li, B;Yan, Z;Fu, J;Wang, W;Zhao, L;Dong, J;Sun, X;Kuang, Y;Sang, Q;Wang, L;, Hum. Genet. 2019 ,PubMed ID 30810869 [pCMV6-Entry]
LINC00261 is an epigenetically-regulated tumor suppressor that is essential for activation of the DNA damage response ,Shahabi, S;Kumaran, V;Castillo, J;Cong, Z;Nandagopal, G;Mullen, DJ;Alvarado, A;Ramos Correa, M;Saizan, A;Goel, R;Bhat, A;Lynch, SK;Zhou, B;Borok, Z;Marconett, CN;, Cancer Res. 2019 ,PubMed ID 30796052 [pCMV6-Entry]
Next Generation Sequencing and Animal Models Reveal SLC9A3R1 as a New Gene Involved in Human Age-Related Hearing Loss ,Girotto, G;Morgan, A;Krishnamoorthy, N;Cocca, M;Brumat, M;Bassani, S;La Bianca, M;Di Stazio, M;Gasparini, P;, Front Genet 2019 ,PubMed ID 30863428 [pCMV6-Entry]
FGFR4 increases EGFR oncogenic signaling in lung adenocarcinoma, and their combined inhibition is highly effective ,Quintanal-Villalonga, A;Molina-Pinelo, S;Yagüe, P;Marrugal, ;Ojeda-Márquez, L;Suarez, R;Ponce-Aix, S;Enguita, A;Carnero, A;Ferrer, I;Paz-Ares, L;, Lung Cancer 2019 ,PubMed ID 31027687 [pCMV6-Entry]
Gold quantum dots impair the tumorigenic potential of glioma stem-like cells via β-catenin downregulation in vitro ,Wahab, R;Kaushik, N;Khan, F;Kaushik, NK;Lee, SJ;Choi, EH;Al-Khedhairy, AA;, Int J Nanomedicine 2019 ,PubMed ID 30863050 [pCMV6-Entry]
Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region ,Izumi, H;Li, Y;Shibaki, M;Mori, D;Yasunami, M;Sato, S;Matsunaga, H;Mae, T;Kodama, K;Kamijo, T;Kaneko, Y;Nakagawara, A;, Sci Rep 2019 ,PubMed ID 30783186 [pCMV6-Entry]
PRDM16 functions as a suppressor of lung adenocarcinoma metastasis ,Fei, LR;Huang, WJ;Wang, Y;Lei, L;Li, ZH;Zheng, YW;Wang, Z;Yang, MQ;Liu, CC;Xu, HT;, J. Exp. Clin. Cancer Res. 2019 ,PubMed ID 30683132 [pCMV6-Entry]
Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells ,Weng, J;Bai, L;Chiu, S;Chiu, C;Lin, W;Hu, J;Shieh, T;, Computational and Structural Biotechnology Journal 2019 ,PubMed ID 30788081 [pCMV6-Entry]
Robo 4 - the double-edged sword in prostate cancer: impact on cancer cell aggressiveness and tumor vasculature ,Pircher, A;Schäfer, G;Eigentler, A;Pichler, R;Puhr, M;Steiner, E;Horninger, W;Gunsilius, E;Klocker, H;Heidegger, I;, Int J Med Sci 2019 ,PubMed ID 30662335 [pCMV6-Entry]
Robo 4-the double-edged sword in prostate cancer: impact on cancer cell aggressiveness and tumor vasculature ,Pircher, A;Schafer, G;Eigentler, A;Pichler, R;, ONCOLOGY 2019 [pCMV6-Entry]
Role of AGAP2 in the profibrogenic effects induced by TGFβ in LX-2 hepatic stellate cells ,Navarro-Corcuera, A;López-Zabalza, MJ;Martínez-Irujo, JJ;Álvarez-Sola, G;Ávila, MA;Iraburu, MJ;Ansorena, E;Montiel-Duarte, C;, Biochim Biophys Acta Mol Cell Res 2019 ,PubMed ID 30660615 [pCMV6-Entry]
FGFR1 cooperates with EGFR in lung cancer oncogenesis, and their combined inhibition shows improved efficacy ,Quintanal-Villalonga, A;Molina-Pinelo, S;Cirauqui, C;Ojeda-Márquez, L;Marrugal, Á;Suarez, R;Conde, E;Ponce-Aix, S;Enguita, AB;Carnero, A;Ferrer, I;Paz-Ares, L;, J Thorac Oncol 2019 ,PubMed ID 30639621 [pCMV6-Entry]
Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth ,Miyake, M;Furuya, H;Onishi, S;Hokutan, K;Anai, S;Chan, O;Shi, S;Fujimoto, K;Goodison, S;Cai, W;Rosser, CJ;, Theranostics 2019 ,PubMed ID 30809313 [pCMV6-Entry]
Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network ,Li, W;Wang, Q;Feng, Q;Wang, F;Yan, Q;Gao, SJ;Lu, C;, PLoS Pathog. 2019 ,PubMed ID 30699189 [pCMV6-Entry]
Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella ,Shen, Y;Zhang, F;Li, F;Jiang, X;Yang, Y;Li, X;Li, W;Wang, X;Cheng, J;Liu, M;Zhang, X;Yuan, G;Pei, X;Cai, K;Hu, F;Sun, J;Yan, L;Tang, L;Jiang, C;Tu, W;Xu, J;Wu, H;Kong, W;Li, S;Wang, K;Sheng, K;Zhao, X;Yue, H;Yang, X;Xu, W;, Nat Commun 2019 ,PubMed ID 30683861 [pCMV6-Entry]
ZNF326 promotes malignant phenotype of glioma by up-regulating HDAC7 expression and activating Wnt pathway ,Yu, X;Wang, M;Wu, J;Han, Q;Zhang, X;, J. Exp. Clin. Cancer Res. 2019 ,PubMed ID 30691485 [pCMV6-Entry]
Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD+ Recycling ,Kim, W;Deik, A;Gonzalez, C;Gonzalez, ME;Fu, F;Ferrari, M;Churchhouse, CL;Florez, JC;Jacobs, SBR;Clish, CB;Rhee, EP;, Cell Metab. 2019 ,PubMed ID 30686744 [pCMV6-Entry]
Ajuba overexpression regulates mitochondrial potential and glucose uptake through YAP/Bcl-xL/GLUT1 in human gastric cancer ,Li, H;Fu, L;Liu, B;Lin, X;Dong, Q;Wang, E;, Gene 2019 ,PubMed ID 30690182 [pCMV6-Entry]
Lipid storage and lipophagy regulates ferroptosis ,Bai, Y;Meng, L;Han, L;Jia, Y;Zhao, Y;Gao, H;Kang, R;Wang, X;Tang, D;Dai, E;, Biochem. Biophys. Res. Commun. 2019 ,PubMed ID 30545638 [pCMV6-Entry]
A key anti-viral protein, RSAD2/VIPERIN, restricts the release of Measles virus in infected cells ,Kurokawa, C;Iankov, ID;Galanis, E;, Virus Res. 2019 ,PubMed ID 30684519 [pCMV6-Entry]
Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression ,Floris, A;Luo, J;Frank, J;Zhou, J;Orrù, S;Biancolella, M;Pucci, S;Orlandi, A;Campagna, P;Balzano, A;Ramani, K;Tomasi, ML;, J. Exp. Clin. Cancer Res. 2019 ,PubMed ID 30611309 [pCMV6-Entry]
Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation ,Dang, T;Meng, X;Modak, C;Wu, J;Chang, Z;Che, N;Narvaez, R;Chai, J;, Cytokine 2019 ,PubMed ID 30685604 [pCMV6-Entry]
ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations ,Graae, AS;Grarup, N;Ribel-Madsen, R;Lystbæk, SH;Boesgaard, T;Staiger, H;Fritsche, A;Wellner, N;Sulek, K;Kjolby, M;Backe, MB;Chubanava, S;Prats, C;Serup, AK;Birk, JB;Dubail, J;Gillberg, L;Vienberg, SG;Nykjær, A;Kiens, B;Wojtaszewski, JFP;Larsen, S;Apte, SS;Häring, HU;Vaag, A;Zethelius, B;Pedersen, O;Treebak, JT;Hansen, T;Holst, B;, Diabetes 2019 ,PubMed ID 30626608 [pCMV6-Entry]
IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity ,Bjune, JI;Haugen, C;Gudbrandsen, O;Nordbø, OP;Nielsen, HJ;Våge, V;Njølstad, PR;Sagen, JV;Dankel, SN;Mellgren, G;, Int J Obes (Lond) 2018 ,PubMed ID 30538277 [pCMV6-Entry]
MicroRNA-214 promotes the calcification of human aortic valve interstitial cells through the acceleration of inflammatory reactions with activated MyD88/NF-κB signaling ,Zheng, D;Zang, Y;Xu, H;Wang, Y;Cao, X;Wang, T;Pan, M;Shi, J;Li, X;, Clin Res Cardiol 2018 ,PubMed ID 30519780 [pCMV6-Entry]
Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects ,Ye, Q;Zhang, Y;Cao, Y;Wang, X;Guo, Y;Chen, J;Horn, J;Ponomareva, LV;Chaiswing, L;Shaaban, KA;Wei, Q;Anderson, BD;St Clair, DK;Zhu, H;Leggas, M;Thorson, JS;She, QB;, Cell Chem Biol 2018 ,PubMed ID 30661989 [pCMV6-Entry]
UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways ,Sreedhar, A;Cassell, T;Smith, P;Lu, D;Nam, HW;Lane, AN;Zhao, Y;, Proteomics 2018 ,PubMed ID 30556651 [pCMV6-Entry]
Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer ,Shintani, T;Higashisaka, K;Maeda, M;Hamada, M;Tsuji, R;Kurihara, K;Kashiwagi, Y;Sato, A;Obana, M;Yamamoto, A;Kawasaki, K;Lin, Y;Kijima, T;Kinehara, Y;Miwa, Y;Maeda, S;Morii, E;Kumanogoh, A;Tsutsumi, Y;Nagatomo, I;Fujio, Y;, Oncotarget 2018 ,PubMed ID 30680067 [pCMV6-Entry]
SMYD3 promotes the epithelial-mesenchymal transition in breast cancer ,Fenizia, C;Bottino, C;Corbetta, S;Fittipaldi, R;Floris, P;Gaudenzi, G;Carra, S;Cotelli, F;Vitale, G;Caretti, G;, Nucleic Acids Res. 2018 ,PubMed ID 30544196 [pCMV6-Entry]
TRIM32 overexpression improves chemoresistance through regulation of mitochondrial function in non-small-cell lung cancers ,Du, Y;Zhang, W;Du, B;Zang, S;Wang, X;Mao, X;Hu, Z;, Onco Targets Ther 2018 ,PubMed ID 30464531 [pCMV6-Entry]
Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer ,Wu, B;Qi, R;Liu, X;Qian, L;Wu, Z;, Onco Targets Ther 2018 ,PubMed ID 30464528 [pCMV6-Entry]
The β subunit of soluble guanylyl cyclase GUCY1B3 exerts cardioprotective effects against ischemic injury via the PKCε/Akt pathway ,Wang, X;Du, W;Li, M;Zhang, Y;Li, H;Sun, K;Liu, J;Dong, P;Meng, X;Yi, W;Yang, L;Zhao, R;Hu, J;, J. Cell. Biochem. 2018 ,PubMed ID 30485489 [pCMV6-Entry]
Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABAA receptors ,Fu, YL;Han, DY;Wang, YJ;Di, XJ;Yu, HB;Mu, TW;, PLoS ONE 2018 ,PubMed ID 30481215 [pCMV6-Entry]
DAZL is a master translational regulator of murine spermatogenesis ,Li, H;Liang, Z;Yang, J;Wang, D;Wang, H;Zhu, M;Geng, B;Xu, E;, bioRxiv 2018 [pCMV6-Entry]
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells ,Cordani, M;Butera, G;Dando, I;Torrens-Mas, M;Butturini, E;Pacchiana, R;Oppici, E;Cavallini, C;Gasperini, S;Tamassia, N;Nadal-Serrano, M;Coan, M;Rossi, D;Gaidano, G;Caraglia, M;Mariotto, S;Spizzo, R;Roca, P;Oliver, J;Scupoli, MT;Donadelli, M;, Br. J. Cancer 2018 ,PubMed ID 30318520 [pCMV6-Entry]
TCF21 inhibits proliferation and chemoresistance through the AKT pathway in human gastric cancer ,Yang, Z;Jiang, X;Li, D;Dong, Q;Zhao, H;Jiang, X;, Gene 2018 ,PubMed ID 30296564 [pCMV6-Entry]
MicroRNA-98 promotes drug resistance and regulates mitochondrial dynamics by targeting LASS2 in bladder cancer cells ,Luan, T;Fu, S;Huang, L;Zuo, Y;Ding, M;Li, N;Chen, J;Wang, H;Wang, J;, Experimental Cell Research 2018 ,PubMed ID 30463687 [pCMV6-Entry]
WAVE2 is associated with poor prognosis in pancreatic cancers and promotes cell motility and invasiveness via binding to ACTN4 ,Taniuchi, K;Furihata, M;Naganuma, S;Saibara, T;, Cancer Med 2018 ,PubMed ID 30353690 [pCMV6-Entry]
FAM129B promoted tumor invasion and proliferation via facilitating the phosphorylation of FAK signaling and associated with adverse clinical outcome of non-small cell lung cancer patients ,Zhou, X;Yang, F;Zhang, Q;Miao, Y;Hu, X;Li, A;Hou, G;Wang, Q;Kang, J;, Onco Targets Ther 2018 ,PubMed ID 30498362 [pCMV6-Entry]
Deguelin attenuates non-small cell lung cancer cell metastasis through inhibiting the CtsZ/FAK signaling pathway ,Li, W;Yu, X;Ma, X;Xie, L;Xia, Z;Liu, L;Yu, X;Wang, J;Zhou, H;Zhou, X;Yang, Y;Liu, H;, Cell. Signal. 2018 ,PubMed ID 30018008 [pCMV6-Entry]
ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer ,Liu, CY;Hsu, CC;Huang, TT;Lee, CH;Chen, JL;Yang, SH;Jiang, JK;Chen, WS;Lee, KD;Teng, HW;, Mol Oncol 2018 ,PubMed ID 30063110 [pCMV6-Entry]
Cullin3-RING ubiquitin ligases are intimately linked to the unfolded protein response of the endoplasmic reticulum ,Kim, K;Park, S;Kim, J;, bioRxiv 2018 [pCMV6-Entry]
Regulatory elements in vectors containing the ctEF-1α first intron and double enhancers for an efficient recombinant protein expression system ,Lee, CP;Ko, AM;Chiang, SL;Lu, CY;Tsai, EM;Ko, YC;, Sci Rep 2018 ,PubMed ID 30337625 [pCMV6-Entry]
The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization ,Gasperini, L;Rossi, A;Cornella, N;Peroni, D;Zuccotti, P;Potrich, V;Quattrone, A;Macchi, P;, Mol. Biol. Cell 2018 ,PubMed ID 30354839 [pCMV6-Entry]
UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy ,Shorrock, HK;van der Hoorn, D;Boyd, PJ;Llavero Hurtado, M;Lamont, DJ;Wirth, B;Sleigh, JN;Schiavo, G;Wishart, TM;Groen, EJN;Gillingwater, TH;, Brain 2018 ,PubMed ID 30239612 [pCMV6-Entry]
Rab14 overexpression regulates gemcitabine sensitivity through regulation of Bcl-2 and mitochondrial function in pancreatic cancer ,Ge, J;Ge, C;, Virchows Arch. 2018 ,PubMed ID 30267303 [pCMV6-Entry]
lncRNA NTT/PBOV1 Axis Promotes Monocyte Differentiation and Is Elevated in Rheumatoid Arthritis ,Yang, CA;Li, JP;Yen, JC;Lai, IL;Ho, YC;Chen, YC;Lan, JL;Chang, JG;, Int J Mol Sci 2018 ,PubMed ID 30231487 [pCMV6-Entry]
ZNF326 promotes a malignant phenotype of breast cancer by interacting with DBC1 ,Yu, X;Wang, M;Han, Q;Zhang, X;Mao, X;Wang, X;Li, X;Ma, W;Jin, F;, Mol. Carcinog. 2018 ,PubMed ID 30175866 [pCMV6-Entry]
CCN1 induces apoptosis in esophageal adenocarcinoma through p53-dependent downregulation of survivin ,Dang, T;Modak, C;Meng, X;Wu, J;Narvaez, R;Chai, J;, J Cell Biochem 2018 ,PubMed ID 30318638 [pCMV6-Entry]
Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia ,Verlekar, D;Wei, SJ;Cho, H;Yang, S;Kang, MH;, Cell Death Dis 2018 ,PubMed ID 30206207 [pCMV6-Entry]
TRIM59 overexpression correlates with poor prognosis and contributes to breast cancer progression through AKT signaling pathway ,Liu, Y;Dong, Y;Zhao, L;Su, L;Diao, K;Mi, X;, Mol. Carcinog. 2018 ,PubMed ID 30175868 [pCMV6-Entry]
Novel tumor suppressor SPRYD4 inhibits tumor progression in hepatocellular carcinoma by inducing apoptotic cell death ,Zahid, KR;Han, S;Zhou, F;Raza, U;, Cell Oncol (Dordr) 2018 ,PubMed ID 30238408 [pCMV6-Entry]
CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts ,Takeshima, H;Horie, M;Mikami, Y;Makita, K;Miyashita, N;Matsuzaki, H;Noguchi, S;Urushiyama, H;Hiraishi, Y;Mitani, A;Borok, Z;Nagase, T;Yamauchi, Y;, Allergol Int 2018 ,PubMed ID 30197185 [pCMV6-Entry]
Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing ,Yuan, T;Wang, S;Hu, C;Wu, Y;Liang, D;Li, L;Liu, Y;Li, J;Chen, YH;, J. Cell. Mol. Med. 2018 ,PubMed ID 30070011 [pCMV6-Entry]
Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively ,Kim, JC;Ha, YJ;Tak, KH;Roh, SA;Kwon, YH;Kim, CW;Yoon, YS;Lee, JL;Park, Y;Kim, SK;Kim, SY;Cho, DH;Kim, YS;, PLoS ONE 2018 ,PubMed ID 30148861 [pCMV6-Entry]
Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury ,Akhmedov, A;Bonetti, NR;Reiner, MF;Spescha, RD;Amstalden, H;Merlini, M;Gaul, DS;Diaz-Cañestro, C;Spescha, RS;Semerano, A;Giacalone, G;Savarese, G;Montecucco, F;Kulic, L;Nitsch, RM;Matter, CM;Kullak-Ublick, GA;Sessa, M;Lüscher, TF;Beer, JH;Liberale, L;Camici, GG;, J. Cereb. Blood Flow Metab. 2018 ,PubMed ID 30073881 [pCMV6-Entry]
The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain ,Cajigas, I;Chakraborty, A;Swyter, KR;Luo, H;Bastidas, M;Nigro, M;Morris, ER;Chen, S;VanGompel, MJW;Leib, D;Kohtz, SJ;Martina, M;Koh, S;Ay, F;Kohtz, JD;, Mol. Cell 2018 ,PubMed ID 30146317 [pCMV6-Entry]
Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress‑related autophagy in hepatocellular carcinoma ,Liu, D;Fan, Y;Li, J;Cheng, B;Lin, W;Li, X;Du, J;Ling, C;, Oncol. Rep. 2018 ,PubMed ID 30066934 [pCMV6-Entry]
CTGF mediates tumor-stroma interactions between hepatoma cells and hepatic stellate cells to accelerate HCC progression ,Makino, Y;Hikita, H;Kodama, T;Shigekawa, M;Yamada, R;Sakamori, R;Eguchi, H;Morii, E;Yokoi, H;Mukoyama, M;Suemizu, H;Tatsumi, T;Takehara, T;, Cancer Res. 2018 ,PubMed ID 29967264 [pCMV6-Entry]
miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2 ,Liu, F;Sang, M;Meng, L;Gu, L;Liu, S;Li, J;Geng, C;, Int. J. Oncol. 2018 ,PubMed ID 30066891 [pCMV6-Entry]
Rab11 Functions as an Oncoprotein via Nuclear Factor kappa B (NF-κB) Signaling Pathway in Human Bladder Carcinoma ,Gong, X;Liu, J;Zhang, X;Dong, F;Liu, Y;Wang, P;, Med. Sci. Monit. 2018 ,PubMed ID 30032159 [pCMV6-Entry]
FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation ,Cui, YH;Kim, H;Lee, M;Yi, JM;Kim, RK;Uddin, N;Yoo, KC;Kang, JH;Choi, MY;Cha, HJ;Kwon, OS;Bae, IH;Kim, MJ;Kaushik, N;Lee, SJ;, Oncogene 2018 ,PubMed ID 29973690 [pCMV6-Entry]
SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts ,Li, M;Xu, X;Chang, CW;Zheng, L;Shen, B;Liu, Y;, Nat Commun 2018 ,PubMed ID 30006506 [pCMV6-Entry]
Structural and functional characterization of the RBBP4-ZNF827 interaction and its role in NuRD recruitment to telomeres ,Yang, SF;Sun, AA;Shi, Y;Li, F;Pickett, HA;, Biochem. J. 2018 ,PubMed ID 30045876 [pCMV6-Entry]
Expression of transmembrane protein 41A is associated with metastasis via the modulation of E‑cadherin in radically resected gastric cancer ,Lin, B;Xue, Y;Qi, C;Chen, X;Mao, W;, Mol Med Rep 2018 ,PubMed ID 30015937 [pCMV6-Entry]
Downregulation of RASSF6 promotes breast cancer growth and chemoresistance through regulation of Hippo signaling ,He, Z;Zhao, TT;Jin, F;Li, JG;Xu, YY;Dong, HT;Liu, Q;Xing, P;Zhu, GL;Xu, H;Miao, ZF;, Biochem. Biophys. Res. Commun. 2018 ,PubMed ID 29964010 [pCMV6-Entry]
Olfactomedin 4 Deletion Improves Male Mouse Glucose Intolerance and Insulin Resistance Induced by a High-Fat Diet ,Liu, W;Aerbajinai, W;Li, H;Liu, Y;Gavrilova, O;Jain, S;Rodgers, GP;, Endocrinology 2018 ,PubMed ID 30052841 [pCMV6-Entry]
MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species ,Vera-Puente, O;Rodriguez-Antolin, C;Salgado-Figueroa, A;Michalska, P;Pernia, O;Reid, BM;Rosas, R;Garcia-Guede, A;SacristÁn, S;Esteban-Rodriguez, I;Martin, ME;Sellers, TA;León, R;Gonzalez, VM;De Castro, J;de Caceres, II;, Transl Res 2018 ,PubMed ID 30053382 [pCMV6-Entry]
Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma ,Kikuchi, H;Sakakibara-Konishi, J;Furuta, M;Kikuchi, E;Kikuchi, J;Oizumi, S;Hida, Y;Kaga, K;Kinoshita, I;Dosaka-Akita, H;Nishimura, M;, Oncotarget 2018 ,PubMed ID 30034624 [pCMV6-Entry]
Ubiquitin-Dependent Degradation of Mitochondrial Proteins Regulates Energy Metabolism ,Lavie, J;De Belvalet, H;Sonon, S;Ion, AM;Dumon, E;Melser, S;Lacombe, D;Dupuy, JW;Lalou, C;Bénard, G;, Cell Rep 2018 ,PubMed ID 29874573 [pCMV6-Entry]
Odd-skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and β-catenin ,Wang, Y;Lei, L;Zheng, YW;Zhang, L;Li, ZH;Shen, HY;Jiang, GY;Zhang, XP;Wang, EH;Xu, HT;, Cancer Sci. 2018 ,PubMed ID 29660200 [pCMV6-Entry]
Activating the pregnane X receptor by imperatorin attenuates dextran sulphate sodium-induced colitis in mice ,Liu, M;Zhang, G;Zheng, C;Song, M;Liu, F;Huang, X;Bai, S;Huang, X;Lin, C;Zhu, C;Hu, Y;Mi, S;Liu, C;, Br. J. Pharmacol. 2018 ,PubMed ID 29945292 [pCMV6-Entry]
Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma ,Ou, D;Lin, Y;Hsu, C;Lin, Y;Chen, C;Yu, J;Miaw, S;Hsu, P;Cheng, A;Hsu, C;, Liver Cancer 2018 [pCMV6-Entry]
Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter ,Navrátilová, L;Applová, L;Horký, P;Mladěnka, P;Pávek, P;Trejtnar, F;, Naunyn Schmiedebergs Arch. Pharmacol. 2018 ,PubMed ID 29934673 [pCMV6-Entry]
SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior ,Brown, TC;Murtha, TD;Rubinstein, JC;Korah, R;Carling, T;, Cell Commun. Signal 2018 ,PubMed ID 29884238 [pCMV6-Entry]
CRP Stimulates GDF15 Expression in Endothelial Cells through p53 ,Kim, Y;Noren Hooten, N;Evans, M;, Mediators of Inflammation 2018 ,PubMed ID 29967567 [pCMV6-Entry]
Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1 ,Wang, H;Chen, Y;Guo, J;Shan, T;Deng, K;Chen, J;Cai, L;Zhou, H;Zhao, Q;Jin, S;Xia, J;, Sci Rep 2018 ,PubMed ID 29728635 [pCMV6-Entry]
ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer ,Guo, Q;Grimmig, T;Gonzalez, G;Giobbie-Hurder, A;Berg, G;Carr, N;Wilson, BJ;Banerjee, P;Ma, J;Gold, JS;Nandi, B;Huang, Q;Waaga-Gasser, AM;Lian, CG;Murphy, GF;Frank, MH;Gasser, M;Frank, NY;, J. Biol. Chem. 2018 ,PubMed ID 29789423 [pCMV6-Entry]
Loss of cyclin-dependent kinase-like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion ,Fang, CL;Uen, YH;Chen, HK;Hseu, YC;Lin, CC;Hung, ST;Sun, DP;Lin, KY;, Cancer Med 2018 ,PubMed ID 29790675 [pCMV6-Entry]
Gremlin2 Regulates the Differentiation and Function of Cardiac Progenitor Cells via the Notch Signaling Pathway ,Li, W;Lu, Y;Han, R;Yue, Q;Song, X;Wang, F;Wu, R;Hou, F;Yang, L;Xu, L;Zhao, R;Hu, J;, Cell. Physiol. Biochem. 2018 ,PubMed ID 29794428 [pCMV6-Entry]
Identification of new phosphorylation sites of CD23 in B-cells of patients with chronic lymphocytic leukemia ,Maďarová, M;Mucha, R;Hresko, S;Makarová, Z;Gdovinová, Z;Szilasiová, J;Vitková, M;Guman, T;Štecová, N;Dobransky, T;, Leuk. Res. 2018 ,PubMed ID 29763855 [pCMV6-Entry]
MicroRNA-599 targets high-mobility group AT-hook 2 to inhibit cell proliferation and invasion in clear cell renal carcinoma ,Zhao, H;Zhao, H;Xia, X;Liu, X;, Mol Med Rep 2018 ,PubMed ID 29568870 [pCMV6-Entry]
Crosstalk of NF-κB/P65 and LncRNA HOTAIR-Mediated Repression of MUC1 Expression Contribute to Synergistic Inhibition of Castration-Resistant Prostate Cancer by Polyphyllin 1-Enzalutamide Combination Treatment ,Xiang, S;Zou, P;Wu, J;Zheng, F;Tang, Q;Zhou, J;Hann, SS;, Cell. Physiol. Biochem. 2018 ,PubMed ID 29807357 [pCMV6-Entry]
Downregulation of miR-491-5p promotes gastric cancer metastasis by regulating SNAIL and FGFR4 ,Yu, T;Wang, LN;Li, W;Zuo, QF;Li, MM;Zou, QM;Xiao, B;, Cancer Sci. 2018 ,PubMed ID 29569792 [pCMV6-Entry]
MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis ,Zhang, W;Yi, X;An, Y;Guo, S;Li, S;Song, P;Chang, Y;Zhang, S;Gao, T;Wang, G;Li, C;, Cell Death Dis 2018 ,PubMed ID 29752469 [pCMV6-Entry]
CD13 overexpression promotes rectal cancer cell proliferation by increasing VEGF expression ,Xu, H;Sun, J;Zhang, Z;, Int J Clin Exp Med 2018 [pCMV6-Entry]
Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis ,Bozza, WP;Zhang, Y;Zhang, B;, Oncotarget 2018 ,PubMed ID 29796187 [pCMV6-Entry]
Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth ,Chiu, M;Taurino, G;Bianchi, MG;Ottaviani, L;Andreoli, R;Ciociola, T;Lagrasta, CAM;Tardito, S;Bussolati, O;, Int J Mol Sci 2018 ,PubMed ID 29642388 [pCMV6-Entry]
Unfractionated Heparin Alleviates Human Lung Endothelial Barrier Dysfunction Induced by High Mobility Group Box 1 Through Regulation of P38-GSK3β-Snail Signaling Pathway ,Luan, Z;Hu, B;Wu, L;Jin, S;Ma, X;Zhang, J;Wang, A;, Cell. Physiol. Biochem. 2018 ,PubMed ID 29719300 [pCMV6-Entry]
Parathyroid hormone-induced down-regulation of miR-532-5p for matrix metalloproteinase-13 expression in rat osteoblasts ,Mohanakrishnan, V;Balasubramanian, A;Mahalingam, G;Partridge, NC;Ramachandran, I;Selvamurugan, N;, J. Cell. Biochem. 2018 ,PubMed ID 29626351 [pCMV6-Entry]
Protein arginine methyltransferase 8 gene enhances the colon cancer stem cell (CSC) function by upregulating the pluripotency transcription factor ,Lin, H;Wang, B;Yu, J;Wang, J;Li, Q;Cao, B;, J Cancer 2018 ,PubMed ID 29721049 [pCMV6-Entry]
TRIM32 promotes proliferation and confers chemoresistance to breast cancer cells through activation of the NF-κB pathway ,Zhao, TT;Jin, F;Li, JG;Xu, YY;Dong, HT;Liu, Q;Xing, P;Zhu, GL;Xu, H;Yin, SC;Miao, ZF;, J Cancer 2018 ,PubMed ID 29721043 [pCMV6-Entry]
Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma ,Yang, G;Fan, G;Zhang, T;Ma, K;Huang, J;Liu, M;Teng, X;Xu, K;Fan, P;Cheng, D;, Med. Sci. Monit. 2018 ,PubMed ID 29627846 [pCMV6-Entry]
Homozygous Mutations in WEE2 Cause Fertilization Failure and Female Infertility ,Sang, Q;Li, B;Kuang, Y;Wang, X;Zhang, Z;Chen, B;Wu, L;Lyu, Q;Fu, Y;Yan, Z;Mao, X;Xu, Y;Mu, J;Li, Q;Jin, L;He, L;Wang, L;, Am. J. Hum. Genet. 2018 ,PubMed ID 29606300 [pCMV6-Entry]
The Role of ADAR1 and ADAR2 in the Regulation of miRNA-21 in Idiopathic Pulmonary Fibrosis ,Díaz-Piña, G;Ordoñez-Razo, RM;Montes, E;Páramo, I;Becerril, C;Salgado, A;Santibañez-Salgado, JA;Maldonado, M;Ruiz, V;, Lung 2018 ,PubMed ID 29637273 [pCMV6-Entry]
Lamin A/C might be involved in the EMT signalling pathway ,Zuo, L;Zhao, H;Yang, R;Wang, L;Ma, H;Xu, X;Zhou, P;Kong, L;, Gene 2018 ,PubMed ID 29665450 [pCMV6-Entry]
Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells ,Chen, B;Liang, Y;Chen, L;Wei, Y;Li, Y;Zhao, W;Wu, J;, J. Cancer 2018 ,PubMed ID 29675106 [pCMV6-Entry]
Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation ,Liu, Y;Liang, X;Dong, W;Fang, Y;Lv, J;Zhang, T;Fiskesund, R;Xie, J;Liu, J;Yin, X;Jin, X;Chen, D;Tang, K;Ma, J;Zhang, H;Yu, J;Yan, J;Liang, H;Mo, S;Cheng, F;Zhou, Y;Zhang, H;Wang, J;Li, J;Chen, Y;Cui, B;Hu, ZW;Cao, X;Xiao-Feng Qin, F;Huang, B;, Cancer Cell 2018 ,PubMed ID 29533786 [pCMV6-Entry]
Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons ,Duan, J;Marcellus, KA;Qin, X;Wang, Y;Paudel, HK;, Mol. Cell. Neurosci. 2018 ,PubMed ID 29577984 [pCMV6-Entry]
BCL7B, a predictor of poor prognosis of pancreatic cancers, promotes cell motility and invasion by influencing CREB signaling ,Taniuchi, K;Furihata, M;Naganuma, S;Dabanaka, K;Hanazaki, K;Saibara, T;, Am J Cancer Res 2018 ,PubMed ID 29636996 [pCMV6-Entry]
MicroRNA-223-3p regulates cell chemo-sensitivity by targeting FOXO3 in prostatic cancer ,Feng, Q;He, P;Wang, Y;, Gene 2018 ,PubMed ID 29518547 [pCMV6-Entry]
Hepatitis C Virus (HCV) Mimics Effects of Glypican-3 (GPC3) on CD81 and Promotes Development of Hepatocellular Carcinomas via Activation of Hippo Pathway in Hepatocytes ,Xue, Y;Mars, WM;Bowen, W;Singhi, AD;Stoops, J;Michalopoulos, GK;, Am. J. Pathol. 2018 ,PubMed ID 29577937 [pCMV6-Entry]
Upregulation of miR-582-5p regulates cell proliferation and apoptosis by targeting AKT3 in human endometrial carcinoma ,Li, L;Ma, L;, Saudi Journal of Biological Sciences 2018 [pCMV6-Entry]
MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma ,Dietrich, P;Kuphal, S;Spruss, T;Hellerbrand, C;Bosserhoff, AK;, Pigment Cell Melanoma Res 2018 ,PubMed ID 29495114 [pCMV6-Entry]
Glyoxalase 1 sustains the metastatic phenotype of prostate cancer cells via EMT control ,Antognelli, C;Cecchetti, R;Riuzzi, F;Peirce, MJ;Talesa, VN;, J. Cell. Mol. Med. 2018 ,PubMed ID 29504694 [pCMV6-Entry]
Probing ligand structure-activity relationships in pregnane X receptor (PXR): efavirenz and 8-hydroxyefavirenz exhibit divergence in activation ,Narayanan, B;Lade, J;Heck, CJS;Dietz, KD;Wade, HV;Bumpus, NN;, ChemMedChem 2018 ,PubMed ID 29430850 [pCMV6-Entry]
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification ,Bento-Abreu, A;Jager, G;Swinnen, B;Rué, L;Hendrickx, S;Jones, A;Staats, KA;Taes, I;Eykens, C;Nonneman, A;Nuyts, R;Timmers, M;Silva, L;Chariot, A;Nguyen, L;Ravits, J;Lemmens, R;Cabooter, D;Ludo, VDB;Van Damme, P;Al-Chalabi, A;Bystrom, A;Robberecht, W;, Hum. Mol. Genet. 2018 ,PubMed ID 29415125 [pCMV6-Entry]
The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction ,Quintanal-Villalonga, Á;Ojeda-Márquez, L;Marrugal, Á;Yagüe, P;Ponce-Aix, S;Salinas, A;Carnero, A;Ferrer, I;Molina-Pinelo, S;Paz-Ares, L;, Sci Rep 2018 ,PubMed ID 29402970 [pCMV6-Entry]
De novo mutations implicate novel genes in systemic lupus erythematosus ,Pullabhatla, V;Roberts, AL;Lewis, MJ;Mauro, D;Morris, DL;Odhams, CA;Tombleson, P;Liljedahl, U;Vyse, S;Simpson, MA;Sauer, S;de Rinaldis, E;Syvänen, AC;Vyse, TJ;, Hum. Mol. Genet. 2018 ,PubMed ID 29177435 [pCMV6-Entry]
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism ,Zhao, L;Guan, H;Song, C;Wang, Y;Liu, C;Cai, C;Zhu, H;Liu, H;Zhao, L;Xiao, J;, Bone 2018 ,PubMed ID 29432919 [pCMV6-Entry]
LASS2 regulates invasion and chemoresistance via ERK/Drp1 modulated mitochondrial dynamics in bladder cancer cells ,Huang, L;Luan, T;Chen, Y;Bao, X;Huang, Y;Fu, S;Wang, H;Wang, J;, J Cancer 2018 ,PubMed ID 29581781 [pCMV6-Entry]
Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production ,Tang, AC;Rahavi, SM;Fung, SY;Lu, HY;Yang, H;Lim, CJ;Reid, GS;Turvey, SE;, Cell Death Dis 2018 ,PubMed ID 29415982 [pcmv6-entry]
Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer ,Tsai, YC;Zeng, T;Abou-Kheir, W;Yeh, HL;Yin, JJ;Lee, YC;Chen, WY;Liu, YN;, Mol. Cancer 2018 ,PubMed ID 29455655 [pCMV6-Entry]
c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer ,He, H;Sinha, I;Fan, R;Haldosen, LA;Yan, F;Zhao, C;Dahlman-Wright, K;, Oncogene 2018 ,PubMed ID 29467493 [pCMV6-Entry]
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1 ,Zhang, X;Jiang, G;Wu, J;Zhou, H;Zhang, Y;Miao, Y;Feng, Y;Yu, J;, Oncol Lett 2018 ,PubMed ID 29556277 [pCMV6-Entry]
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling ,Yang, Y;Qi, Q;Wang, Y;Shi, Y;Yang, W;Cen, Y;Zhu, E;Li, X;Chen, D;Wang, B;, The FASEB Journal 2018 ,PubMed ID 29401606 [pCMV6-Entry]
Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin ,Herroon, MK;Rajagurubandara, E;Diedrich, JD;Heath, EI;Podgorski, I;, Sci Rep 2018 ,PubMed ID 29311669 [pCMV6-Entry]
MiR-205 enhances cisplatin sensitivity of glioma cells by targeting E2F1 ,Li, FF;Xing, C;Wu, LL;Xue, F;, Eur Rev Med Pharmacol Sci 2018 ,PubMed ID 29424887 [pCMV6-Entry]
Upregulation and Nuclear Location of MMP28 in Alveolar Epithelium of Idiopathic Pulmonary Fibrosis ,Maldonado, M;Salgado-Aguayo, A;Herrera, I;Cabrera, S;Ortíz-Quintero, B;Staab-Weijnitz, CA;Eickelberg, O;Ramírez, R;Manicone, AM;Selman, M;Pardo, A;, Am. J. Respir. Cell Mol. Biol. 2018 ,PubMed ID 29373068 [pCMV6-Entry]
Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways ,Chen, K;Liu, MX;Mak, CS;Yung, MM;Leung, TH;Xu, D;Ngu, SF;Chan, KK;Yang, H;Ngan, HY;Chan, DW;, Theranostics 2018 ,PubMed ID 29290818 [pCMV6-Entry]
Decreased ZONAB expression promotes excessive transdifferentiation of alveolar epithelial cells in hyperoxia-induced bronchopulmonary dysplasia ,Hou, A;Fu, J;Shi, Y;Qiao, L;Li, J;Xing, Y;Xue, X;, Int J Mol Med 2018 ,PubMed ID 29393348 [pCMV6-Entry]
Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl-xL silenced cells ,Premkumar, DR;Jane, EP;Thambireddy, S;Sutera, PA;Cavaleri, JM;Pollack, IF;, Mol. Carcinog. 2017 ,PubMed ID 29240261 [pCMV6-Entry]
CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma ,Zhang, T;Ma, K;Huang, J;Wang, S;Liu, Y;Fan, G;Liu, M;Yang, G;Wang, C;Fan, P;, Oncotarget 2017 ,PubMed ID 29299129 [pCMV6-Entry]
Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression ,Kang, YE;Kim, JM;Kim, KS;Chang, JY;Jung, M;Lee, J;Yi, S;Kim, HW;Kim, JT;Lee, K;Choi, MJ;Kang, SK;Lee, SE;Yi, HS;Koo, BS;Shong, M;, Oncotarget 2017 ,PubMed ID 29383135 [pCMV6-Entry]
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator ,Carayol, J;Chabert, C;Di Cara, A;Armenise, C;Lefebvre, G;Langin, D;Viguerie, N;Metairon, S;Saris, WHM;Astrup, A;Descombes, P;Valsesia, A;Hager, J;, Nat Commun 2017 ,PubMed ID 29234017 [pCMV6-Entry]
WBSCR22 confers oxaliplatin resistance in human colorectal cancer ,Yan, D;Tu, L;Yuan, H;Fang, J;Cheng, L;Zheng, X;Wang, X;, Sci Rep 2017 ,PubMed ID 29133897 [pCMV6-Entry]
ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1 ,Tyagi, N;Deshmukh, SK;Srivastava, SK;Azim, S;Ahmad, A;Al-Ghadhban, A;Singh, AP;Carter, JE;Wang, B;Singh, S;, Mol. Cancer Res.2017 ,PubMed ID 29117940 [pCMV6-Entry]
Polo-Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes-Associated Protein 1 in Cardiac Progenitor Cells ,Mochizuki, M;Lorenz, V;Ivanek, R;Della Verde, G;Gaudiello, E;Marsano, A;Pfister, O;Kuster, GM;, J Am Heart Assoc 2017 ,PubMed ID 29066438 [pCMV6-Entry]
Livin promotes the progression and metastasis of breast cancer through the regulation of epithelial‑mesenchymal transition via the p38/GSK3β pathway ,Han, Y;Zhang, L;Wang, W;Li, J;Song, M;, Oncol. Rep. 2017 ,PubMed ID 29039608 [pCMV6-Entry]
NEAT1 regulates cell proliferation and apoptosis of ovarian cancer by miR-34a-5p/BCL2 ,Ding, N;Wu, H;Tao, T;Peng, E;, Onco Targets Ther 2017 ,PubMed ID 29062236 [pCMV6-Entry]
ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells ,Piao, S;Ojha, R;Rebecca, VW;Samanta, A;Ma, XH;Mcafee, Q;Nicastri, MC;Buckley, M;Brown, E;Winkler, JD;Gimotty, PA;Amaravadi, RK;, Autophagy 2017 ,PubMed ID 28981387 [pCMV6-Entry]
TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer ,Liu, L;Zhou, XM;Yang, FF;Miao, Y;Yin, Y;Hu, XJ;Hou, G;Wang, QY;Kang, J;, Oncotarget 2017 ,PubMed ID 28977927 [pCMV6-Entry]
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway ,Zhang, X;Zhang, Y;Miao, Y;Zhou, H;Jiang, G;Wang, E;, Oncotarget 2017 ,PubMed ID 29050311 [pCMV6-Entry]
Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells ,Campfield, BT;Eddens, T;Henkel, M;Majewski, M;Horne, W;Chaly, Y;Gaffen, SL;Hirsch, R;Kolls, JK;, Immunol. Cell Biol. 2017 ,PubMed ID 28377613 [pCMV6-Entry]
Musashi-1 Enhances Glioblastoma Cell Migration and Cytoskeletal Dynamics through Translational Inhibition of Tensin3 ,Chen, HY;Lin, LT;Wang, ML;Laurent, B;Hsu, CH;Pan, CM;Jiang, WR;Chen, PY;Ma, HI;Chen, YW;Huang, PI;Chiou, A;Chiou, SH;, Sci Rep 2017 ,PubMed ID 28821879 [pCMV6-Entry]
TGF-β1/ALK5-mediated cell migration is dependent on the protein PAR2 but not on PAR2-stimulated Gq-calcium signaling ,Ungefroren, H;Witte, D;Mihara, K;Rauch, BH;Henklein, P;Johren, O;Bonni, S;Settmacher, U;Lehnert, H;Hollenberg, MD;Kaufmann, R;Gieseler, F;, Mol. Pharmacol. 2017 ,PubMed ID 28842394 [pCMV6-Entry]
ZNF23 Suppresses Cutaneous Melanoma Cell Malignancy via Mitochondria-Dependent Pathway ,Zhang, X;Ding, C;Tian, H;Dong, X;Meng, X;Zhu, W;Liu, B;Wang, L;Huang, M;Li, C;, Cell. Physiol. Biochem. 2017 ,PubMed ID 28848158 [pCMV6-Entry]
MicroRNA‑744 inhibits tumor cell proliferation and invasion of gastric cancer via targeting brain‑derived neurotrophic factor ,Xu, AJ;Fu, LN;Wu, HX;Yao, XL;Meng, R;, Mol Med Rep 2017 ,PubMed ID 28791400 [PCMV6-Entry]
Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling ,Zhang, D;Lu, C;Ai, H;, Mol Med Rep 2017 ,PubMed ID 28849149 [PCMV6-Entry]
Involvement of Cryptosporidium parvum Cdg7_Flc_1000 RNA in the Attenuation of Intestinal Epithelial Cell Migration via Trans-suppression of Host Cell SMPD3 Gene ,Ming, Z;Gong, A-;Wang, Y;Zhang, Xn;Li, M;Mathy, NW;Soukup, JK;Chen, XM;, The Journal of Infectious Diseases 2017 ,PubMed ID 28961856 [PCMV6-Entry]
RPS27a enhances EBV-encoded LMP1-mediated proliferation and invasion by stabilizing of LMP1 ,Hong, SW;Kim, SM;Jin, DH;Kim, YS;Hur, DY;, Biochem. Biophys. Res. Commun. 2017 ,PubMed ID 28735865 [pCMV6-Entry]
Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro ,Navrátilová, L;Mandíková, JR;Pávek, P;Mladěnka, P;Trejtnar, F;, Xenobiotica 2017 ,PubMed ID 28745105 [pCMV6-Entry]
GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition ,Enane, FO;Shuen, WH;Gu, X;Quteba, E;Przychodzen, B;Makishima, H;Bodo, J;Ng, J;Chee, CL;Ba, R;Seng Koh, L;Lim, J;Cheong, R;Teo, M;Hu, Z;Ng, KP;Maciejewski, J;Radivoyevitch, T;Chung, A;Ooi, LL;Tan, YM;Cheow, PC;Chow, P;Chan, CY;Lim, KH;Yerian, L;Hsi, E;Toh, HC;Saunthararajah, Y;, J. Clin. Invest. 2017 ,PubMed ID 28758902 [PCMV6-Entry]
Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine ,Pagel, R;Bär, F;Schröder, T;Sünderhauf, A;Künstner, A;Ibrahim, SM;Autenrieth, SE;Kalies, K;König, P;Tsang, AH;Bettenworth, D;Divanovic, S;Lehnert, H;Fellermann, K;Oster, H;Derer, S;Sina, C;, FASEB J. 2017 ,PubMed ID 28710114 [pCMV6-Entry]
Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis ,Wang, Y;Liu, Z;Yao, B;Li, Q;Wang, L;Wang, C;Dou, C;Xu, M;Liu, Q;Tu, K;, Mol. Cancer 2017 ,PubMed ID 28716020 [pCMV6-Entry]
RA-Induced Transcriptional Silencing of Checkpoint Kinase-2 through Promoter Methylation by Dnmt3b Is Required for Neuronal Differentiation of P19 Cells ,Sheikh, MA;Malik, YS;Zhu, X;, J. Mol. Biol. 2017 ,PubMed ID 28712951 [pCMV6-Entry]
Cerebellar degeneration-related proteins 2 and 2-like are present in ovarian cancer in patients with and without Yo antibodies ,Raspotnig, M;Haugen, M;Thorsteinsdottir, M;Stefansson, I;Salvesen, HB;Storstein, A;Vedeler, CA;, Cancer Immunol. Immunother. 2017 ,PubMed ID 28710511 [pCMV6-Entry]
Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis ,Tsuji, G;Hashimoto-Hachiya, A;Kiyomatsu-Oda, M;Takemura, M;Ohno, F;Ito, T;Morino-Koga, S;Mitoma, C;Nakahara, T;Uchi, H;Furue, M;, Cell Death Dis 2017 ,PubMed ID 28703805 [pCMV6-Entry]
Deregulation of WNT2/FZD3/β-catenin pathway compromises the estrogen synthesis in cumulus cells from patients with polycystic ovary syndrome ,Qiao, GY;Dong, BW;Zhu, CJ;Yan, CY;Chen, BL;, Biochem. Biophys. Res. Commun. 2017 ,PubMed ID 28709873 [pCMV6-Entry]
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients ,Zhang, X;Zhou, H;Zhang, Y;Cai, L;Jiang, G;Li, A;Miao, Y;Li, Q;Qiu, X;Wang, E;, Oncotarget 2017 ,PubMed ID 28418919 [pCMV6-Entry]
Sulfatase-2 promotes the growth and metastasis of colorectal cancer by activating Akt and Erk1/2 pathways ,Tao, Y;Han, T;Zhang, T;Sun, C;, Biomed. Pharmacother. 2017 ,PubMed ID 28320104 [pCMV6-Entry]
Caveolin-1-Autophagy Pathway Mediated Cardiomyocyte Hypertrophy Induced by Apelin-13 ,Wu, D;Xie, F;Xiao, L;Feng, F;Huang, S;He, L;Liu, M;Zhou, Q;Li, L;Chen, L;, DNA Cell Biol. 2017 ,PubMed ID 28537760 [pCMV6-Entry]
Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma ,Duivenvoorden, WCM;Hopmans, SN;Austin, RC;Pinthus, JH;, Oncol Lett 2017 ,PubMed ID 28521463 [pCMV6-Entry]
Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol ,Lin, AH;Liu, MH;Ko, HB;Perng, DW;Lee, TS;Kou, YR;, Front Physiol 2017 ,PubMed ID 28496415 [pCMV6-Entry]
Clinical value of R-spondins in triple-negative and metaplastic breast cancers ,Coussy, F;Lallemand, F;Vacher, S;Schnitzler, A;Chemlali, W;Caly, M;Nicolas, A;Richon, S;Meseure, D;El Botty, R;De-Plater, L;Fuhrmann, L;Dubois, T;Roman-Roman, S;Dangles-Marie, V;Marangoni, E;Bièche, I;, Br. J. Cancer 2017 ,PubMed ID 28472820 [pCMV6-Entry]
FSCN1 is upregulated by SNAI2 and promotes epithelial to mesenchymal transition in head and necksquamous cell carcinoma ,Wang, L;Jia, Y;Jiang, Z;Gao, W;Wang, B;, Cell Biol. Int. 2017 ,PubMed ID 28488774 [pCMV6-Entry]
Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors ,Özata, DM;Li, X;Lee, L;Liu, J;Warsito, D;Hajeri, P;Hultman, I;Fotouhi, O;Marklund, S;Ährlund-Richter, L;Juhlin, CC;Larsson, C;Lui, WO;, Cell Death Dis 2017 ,PubMed ID 28471449 [pCMV6-Entry]
Macrophage-specific nanotechnology-driven CD163 overexpression in human macrophages results in an M2 phenotype under inflammatory conditions ,Alvarado-Vazquez, PA;Bernal, L;Paige, CA;Grosick, RL;Moracho Vilrriales, C;Ferreira, DW;Ulecia-Morón, C;Romero-Sandoval, EA;, Immunobiology 2017 ,PubMed ID 28545809 [pCMV6-Entry]
Dual CDK4/6 Inhibition by PD-0332991 induces apoptosis and senescence in esophageal squamous cell carcinoma cells ,Chen, L;Pan, J;, Br. J. Pharmacol. 2017 ,PubMed ID 28444744 [pCMV6-Entry]
Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers ,Di Mauro, C;Rosa, R;D'Amato, V;Ciciola, P;Servetto, A;Marciano, R;Orsini, RC;Formisano, L;De Falco, S;Cicatiello, V;Di Bonito, M;Cantile, M;Collina, F;Chambery, A;Veneziani, BM;De Placido, S;Bianco, R;, Br. J. Cancer 2017 ,PubMed ID 28441382 [pCMV6-Entry]
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients ,Zhang, X;Zhou, H;Cai, L;Fan, C;Liu, Y;Wang, L;Li, Q;Miao, Y;, Mol. Carcinog. 2017 ,PubMed ID 28398603 [pCMV6-Entry]
A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma ,Tomić, TT;Olausson, J;Wilzén, A;Sabel, M;Truvé, K;Sjögren, H;Dósa, S;Tisell, M;Lannering, B;Enlund, F;Martinsson, T;Åman, P;Abel, F;, PLoS ONE 2017 ,PubMed ID 28448514 [pCMV6-Entry]
CCDC106 promotes non-small cell lung cancer cell proliferation ,Zhang, X;Zheng, Q;Wang, C;Zhou, H;Jiang, G;Miao, Y;Zhang, Y;Liu, Y;Li, Q;Qiu, X;Wang, E;, Oncotarget 2017 ,PubMed ID 28460455 [pCMV6-Entry]
Deficiency of CCN5/WISP-2-Driven Program in breast cancer Promotes Cancer Epithelial cells to mesenchymal stem cells and Breast Cancer growth ,Das, A;Dhar, K;Maity, G;Sarkar, S;Ghosh, A;Haque, I;Dhar, G;Banerjee, S;Banerjee, SK;, Sci Rep 2017 ,PubMed ID 28450698 [pCMV6-Entry]
A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III ,Maio, N;Kim, KS;Singh, A;Rouault, TA;, Cell Metab. 2017 ,PubMed ID 28380382 [pCMV6-Entry]
iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling ,Xiong, Y;Sun, F;Dong, P;Watari, H;Yue, J;Yu, MF;Lan, CY;Wang, Y;Ma, ZB;, J. Exp. Clin. Cancer Res. 2017 ,PubMed ID 28399926 [pCMV6-Entry]
Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation ,Gerarduzzi, C;Kumar, RK;Trivedi, P;Ajay, AK;Iyer, A;Boswell, S;Hutchinson, JN;Waikar, SS;Vaidya, VS;, JCI Insight 2017 ,PubMed ID 28422762 [pCMV6-Entry]
Rab11a promotes proliferation and invasion through regulation of YAP in non-small cell lung cancer ,Dong, Q;Fu, L;Zhao, Y;Du, Y;Li, Q;Qiu, X;Wang, E;, Oncotarget 2017 ,PubMed ID 28468127 [pCMV6-Entry]
Down-Regulation of MicroRNA-210 Confers Sensitivity towards 1'S-1'-Acetoxychavicol Acetate (ACA) in Cervical Cancer Cells by Targeting SMAD4 ,Phuah, NH;Azmi, MN;Awang, K;Nagoor, NH;, Mol. Cells 2017 ,PubMed ID 28401751 [pCMV6-Entry]
Ca(2+) and Calpain Mediate Capsaicin-induced Ablation of Axonal Terminals Expressing Transient Receptor Potential Vanilloid 1 ,Wang, S;Wang, S;Asgar, J;Joseph, J;Ro, JY;Wei, F;Campbell, JN;Chung, MK;, J. Biol. Chem. 2017 ,PubMed ID 28360106 [pCMV6-Entry]
SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage ,Jangi, M;Fleet, C;Cullen, P;Gupta, SV;Mekhoubad, S;Chiao, E;Allaire, N;Bennett, CF;Rigo, F;Krainer, AR;Hurt, JA;Carulli, JP;Staropoli, JF;, Proc. Natl. Acad. Sci. U.S.A 2017 ,PubMed ID 28270613 [pCMV6-Entry]
A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis ,Cheng, JY;Brown, TC;Murtha, TD;Stenman, A;Juhlin, CC;Larsson, C;Healy, JM;Prasad, ML;Knoefel, WT;Krieg, A;Scholl, UI;Korah, R;Carling, T;, BMC Cancer 2017 ,PubMed ID 28249601 [pCMV6-Entry]
Depletion of Gangliosides Enhances Articular Cartilage Repair in Mice ,Matsuoka, M;Onodera, T;Homan, K;Sasazawa, F;Furukawa, JI;Momma, D;Baba, R;Hontani, K;Joutoku, Z;Matsubara, S;Yamashita, T;Iwasaki, N;, Sci Rep 2017 ,PubMed ID 28252046 [pCMV6-Entry]
Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma ,McGrady, NR;Minton, AZ;Stankowska, DL;He, S;Jefferies, HB;Krishnamoorthy, RR;, BMC Neurosci 2017 ,PubMed ID 28249604 [pCMV6-Entry]
Suppression of microRNA-629 enhances sensitivity of cervical cancer cells to 1'S-1'-acetoxychavicol acetate via regulating RSU1 ,Phuah, NH;Azmi, MN;Awang, K;Nagoor, NH;, Onco Targets Ther 2017 ,PubMed ID 28356756 [pCMV6-Entry]
MicroRNA-320 inhibits invasion and induces apoptosis by targeting CRKL and inhibiting ERK and AKT signaling in gastric cancer cells ,Zhao, Y;Dong, Q;Wang, E;, Onco Targets Ther 2017 ,PubMed ID 28255248 [pCMV6-Entry]
Differential activation of pregnane X receptor by carnosic acid, carnosol, ursolic acid, and rosmarinic acid ,Seow, CL;Lau, AJ;, Pharmacol. Res 2017 ,PubMed ID 28288941 [pCMV6-Entry]
DDA1 is induced by NR2F6 in ovarian cancer and predicts poor survival outcome ,Liu, J;Li, T;Liu, XL;, Eur Rev Med Pharmacol Sci 2017 ,PubMed ID 28387912 [pCMV6-Entry]
Elevated Expression of SCGB1D2 Predicts Unfavorable Prognosis in Patients with Pancreatic Ductal Adenocarcinoma ,Taniuchi, K;Furihata, M;Naganuma, S;Kimura, M;Watanabe, R;Mizuta, H;Okamoto, N;Kohsaki, T;Dabanaka, K;Hanazaki, K;Saibara, T;, Journal of the Pancreas 2017 [pCMV6-Entry]
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes ,Almine, JF;O'Hare, CA;Dunphy, G;Haga, IR;Naik, RJ;Atrih, A;Connolly, DJ;Taylor, J;Kelsall, IR;Bowie, AG;Beard, PM;Unterholzner, L;, Nat Commun 2017 ,PubMed ID 28194029 [pCMV6-Entry]
Calumenin contributes to ER-Ca(2+) homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention ,Philippe, R;Antigny, F;Buscaglia, P;Norez, C;Huguet, F;Castelbou, C;Trouvé, P;Becq, F;Frieden, M;Férec, C;Mignen, O;, Cell Calcium 2017 ,PubMed ID 28189267 [pCMV6-Entry]
Faithful SGCE imprinting in iPSC-derived cortical neurons: an endogenous cellular model of myoclonus-dystonia ,Grütz, K;Seibler, P;Weissbach, A;Lohmann, K;Carlisle, FA;Blake, DJ;Westenberger, A;Klein, C;Grünewald, A;, Sci Rep 2017 ,PubMed ID 28155872 [pCMV6-Entry]
Two novel BMP-2 variants identified in patients with thoracic ossification of the ligamentum flavum ,Qu, X;Chen, Z;Fan, D;Xiang, S;Sun, C;Zeng, Y;Li, W;Guo, Z;Qi, Q;Zhong, W;Jiang, Y;, Eur. J. Hum. Genet 2017 ,PubMed ID 28145426 [pCMV6-Entry]
AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78 ,Chen, HH;Chen, CC;Lin, YS;Lin, CF;Chen, CL;Chang, CP;, Antiviral Res 2017 ,PubMed ID 28238876 [pCMV6-Entry]
The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition ,Oh, JH;Hur, H;Lee, JY;Kim, Y;Seo, Y;Kim, MH;, Sci Rep 2017 ,PubMed ID 28181567 [pCMV6-Entry]
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway ,Zhang, X;Jiang, G;Sun, M;Zhou, H;Miao, Y;Liang, M;Wang, E;Zhang, Y;, Oncotarget 2017 ,PubMed ID 28076326 [pCMV6-Entry]
Osteogenesis is improved by low Tumour Necrosis factor-α concentration through the modulation of Gs-coupled receptor signals ,Daniele, S;Natali, L;Giacomelli, C;Campiglia, P;Novellino, E;Martini, C;Trincavelli, ML;, Mol. Cell. Biol 2017 ,PubMed ID 28137910 [pCMV6-Entry]
Clinically Distinct Phenotypes of Canavan Disease Correlate with Residual Aspartoacylase Enzyme Activity ,Mendes, MI;Smith, DE;Pop, A;Lennertz, P;Ojeda, MR;Kanhai, WA;van Dooren, SJ;Anikster, Y;Baric, I;Boelen, C;Campistol, J;de Boer, L;Kariminejad, A;Kayserili, H;Roubertie, A;Verbruggen, KT;Vianey-Saban, C;Williams, M;Salomons, GS;, Hum. Mutat 2017 ,PubMed ID 28101991 [pCMV6-Entry]
Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development ,Li, Z;Chen, G;Yang, Y;Guo, W;Tian, W;, Mol Med Rep 2017 ,PubMed ID 27959403
Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis ,Zhang, Y;Thayele Purayil, H;Black, JB;Fetto, F;Lynch, LD;Masannat, JN;Daaka, Y;, Cancer Lett 2017 ,PubMed ID 28104442 [pCMV6-Entry]
miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation ,Ehrlich, L;Hall, C;Venter, J;Dostal, D;Bernuzzi, F;Invernizzi, P;Meng, F;Trzeciakowski, JP;Zhou, T;Standeford, H;Alpini, G;Lairmore, TC;Glaser, S;, Am. J. Pathol 2017 ,PubMed ID 28087162 [pCMV6-Entry]
Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance ,Zhang, M;Osisami, M;Dai, J;Keller, JM;Escara-Wilke, J;Mizokami, A;Keller, ET;, Mol. Cancer Res 2017 ,PubMed ID 28087740 [pCMV6-Entry]
Cathepsin K modulates invasion, migration, and adhesion of oral squamous cell carcinomas in vitro ,Yamashita, K;Iwatake, M;Okamoto, K;Yamada, SI;Umeda, M;Tsukuba, T;, Oral Dis 2017 ,PubMed ID 28117540 [pCMV6-Entry]
MicroRNA-144-3p suppresses gastric cancer progression by inhibiting epithelial-to-mesenchymal transition through targeting PBX3 ,Li, B;Zhang, S;Shen, H;Li, C;, Biochem. Biophys. Res. Commun 2017 ,PubMed ID 28111340 [pCMV6-Entry]
SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers ,Altenberger, C;Heller, G;Ziegler, B;Tomasich, E;Marhold, M;Topakian, T;Müllauer, L;Heffeter, P;Lang, G;End-Pfützenreuter, A;Döme, B;Arns, BM;Klepetko, W;Zielinski, CC;Zöchbauer-Müller, S;, Mol. Cancer 2017 ,PubMed ID 28093071 [pCMV6-Entry]
EphA2 is a functional receptor for the growth factor progranulin ,Neill, T;Buraschi, S;Goyal, A;Sharpe, C;Natkanski, E;Schaefer, L;Morrione, A;Iozzo, RV;, J. Cell Biol. 2016 ,PubMed ID 27903606
SIRT4 inhibits malignancy progression of NSCLCs, through mitochondrial dynamics mediated by the ERK-Drp1 pathway ,Fu, L;Dong, Q;He, J;Wang, X;Xing, J;Wang, E;Qiu, X;Li, Q;, Oncogene 2016 ,PubMed ID 27941873
Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas ,Bogachek, MV;Park, JM;De Andrade, JP;Lorenzen, AW;Kulak, MV;White, JR;Gu, VW;Wu, VT;Weigel, RJ;, Stem Cell Reports 2016 ,PubMed ID 27916539
CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells ,Tanouchi, A;Taniuchi, K;Furihata, M;Naganuma, S;Dabanaka, K;Kimura, M;Watanabe, R;Kohsaki, T;Shimizu, T;Saito, M;Hanazaki, K;Saibara, T;, J. Exp. Clin. Cancer Res 2016 ,PubMed ID 27919290
25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation ,Shrivastava-Ranjan, P;Bergeron, É;Chakrabarti, AK;Albariño, CG;Flint, M;Nichol, ST;Spiropoulou, CF;, MBio 2016 ,PubMed ID 27999160 [pCMV6-Entry]
Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase ,Sahu, D;Gupta, S;Hau, AM;Nakashima, K;Leivo, MZ;Searles, SC;Elson, P;Bomalaski, JS;Casteel, DE;Boss, GR;Hansel, DE;, The American Journal of Pathology 2016 ,PubMed ID 27979310 [pCMV6-Entry]
Insulinotropic effects of GPR120 agonists are altered in obese non-diabetic and diabetic states ,Zhang, D;So, WY;Wang, Y;Wu, SY;Cheng, Q;Leung, PS;, Clin. Sci 2016 ,PubMed ID 27980130
The differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferation ,Stuqui, B;Conceição, AL;Termini, L;Sichero, L;Villa, LL;Rahal, P;Calmon, MF;, BMC Cancer 2016 ,PubMed ID 27809811
Suppression of cytochrome P450 4B1: An early event in adrenocortical tumorigenesis ,Murtha, TD;Korah, R;Carling, T;, Surgery 2016 ,PubMed ID 27865598
PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition ,Wang, S;Li, C;Wang, W;Xing, C;, Oncol Lett 2016 ,PubMed ID 27900025
Redoxdependent regulation of hepatocyte AIM2 inflammasome activation in sterile liver injury in mice ,Sun, Q;Loughran, P;Shapiro, R;Shrivastava, IH;Antoine, DJ;Li, T;Yan, Z;Fan, J;Billiar, TR;Scott, MJ;, Hepatology 2016
Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR ,Sagara, A;Igarashi, K;Otsuka, M;Karasawa, T;Gotoh, N;Narita, M;Kuzumaki, N;Narita, M;Kato, Y;, PLoS ONE 2016 ,PubMed ID 27723829
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer ,Diaz-Lagares, A;Crujeiras, AB;Lopez-Serra, P;Soler, M;Setien, F;Goyal, A;Sandoval, J;Hashimoto, Y;Martinez-Cardús, A;Gomez, A;Heyn, H;Moutinho, C;Espada, J;Vidal, A;Paúles, M;Galán, M;Sala, N;Akiyama, Y;Martínez-Iniesta, M;Farré, L;Villanueva, A;Gross, M;Diederichs, S;Guil, S;Esteller, M;, Proc. Natl. Acad. Sci. U.S.A. 2016 ,PubMed ID 27821766
Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons ,Takeuchi, S;Iwama, S;Takagi, H;Kiyota, A;Nakashima, K;Izumida, H;Fujisawa, H;Iwata, N;Suga, H;Watanabe, T;Kaibuchi, K;Oiso, Y;Arima, H;Sugimura, Y;, PLoS ONE 2016 ,PubMed ID 27732637
SOX17 is a tumor suppressor in endometrial cancer ,Zhang, Y;Bao, W;Wang, K;Lu, W;Wang, H;Tong, H;Wan, X;, Oncotarget 2016 ,PubMed ID 27738313 [pCMV6-Entry]
Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in BclxL silenced glioma cell lines ,Jane, EP;Premkumar, DR;Sutera, PA;Cavaleri, JM;Pollack, IF;, Molecular carcinogenesis 2016 ,PubMed ID 27805285
IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma ,Qi, L;Yu, H;Zhang, Y;Zhao, D;Lv, P;Zhong, Y;Xu, Y;, Oncotarget 2016 ,PubMed ID 27765933 [pCMV6-Entry]
Simvastatin Up-Regulates Annexin A10 That Can Inhibit the Proliferation, Migration, and Invasion in Androgen-Independent Human Prostate Cancer Cells ,Miyazawa, Y;Sekine, Y;Kato, H;Furuya, Y;Koike, H;Suzuki, K;, The Prostate 2016 ,PubMed ID 27862098
Development of an In Vitro Model to Screen CYP1B1-Targeted Anticancer Prodrugs ,Wang, Z;Chen, Y;Drbohlav, LM;Wu, JQ;Wang, MZ;, Journal of Biomolecular Screening 2016 ,PubMed ID 28139960
The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression ,Lowe, JM;Nguyen, TA;Grimm, SA;Gabor, KA;Peddada, SD;Li, L;Anderson, CW;Resnick, MA;Menendez, D;Fessler, MB;, Cell Death Differ. 2016 ,PubMed ID 27834950
Activation of AMPK mediates additive effects of solamargine and metformin on suppressing MUC1 expression in castration-resistant prostate cancer cells ,SongTaoXiang, ;Zhang, Q;QingTang, ;Zheng, F;JingJingWu, ;LiJunYang, ;Hann, SS;, Scientific Report 2016 ,PubMed ID 27830724
Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells ,Jiao, X;Li, Y;Zhang, T;Liu, M;Chi, Y;, Biochem. Biophys. Res. Commun. 2016 ,PubMed ID 27773814
Impact of Sulfatase-2 on cancer progression and prognosis in patients with renal cell carcinoma ,Kumagai, S;Ishibashi, K;Kataoka, M;Oguro, T;Kiko, Y;Yanagida, T;Aikawa, K;Kojima, Y;, Cancer Sci 2016 ,PubMed ID 27589337
Redox-dependent regulation of hepatocyte absent in melanoma 2 inflammasome activation in sterile liver injury in mice ,Sun, Q;Loughran, P;Shapiro, R;Shrivastava, IH;Antoine, DJ;Li, T;Yan, Z;Fan, J;Billiar, TR;Scott, MJ;, Hepatology 2016 ,PubMed ID 27774630 [pCMV6-Entry]
Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response ,Burgess, JT;Bolderson, E;Adams, MN;Baird, AM;Zhang, SD;Gately, KA;Umezawa, K;O'Byrne, KJ;Richard, DJ;, Cell Death Dis 2016 ,PubMed ID 27831555
Correction: Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion ,Gaitanos, TN;Koerner, J;Klein, R;, J. Cell Biol. 2016 ,PubMed ID 27799372
Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone ,Terayama, H;Hirai, S;Naito, M;Qu, N;Katagiri, C;Nagahori, K;Hayashi, S;Sasaki, H;Moriya, S;Hiramoto, M;Miyazawa, K;Hatayama, N;Li, ZL;Sakabe, K;Matsushita, M;Itoh, M;, Sci Rep 2016 ,PubMed ID 27752123
Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance ,Kim, Y;Kobayashi, E;Kubota, D;Suehara, Y;Mukaihara, K;Akaike, K;Ito, A;Kaneko, K;Chuman, H;Kawai, A;Kitano, S;, Oncotarget 2016 ,PubMed ID 27683125 [pCMV6-Entry]
HCRP1 is downregulated in non-small cell lung cancer and regulates proliferation, invasion, and drug resistance ,Du, Y;Wang, P;Sun, H;Yang, J;Lang, X;Wang, Z;Zang, S;Chen, L;Ma, J;Sun, D;, Tumour Biol. 2016 ,PubMed ID 27739029
Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model ,Yao, X;Wu, J;Lin, M;Sun, W;He, X;Gowda, C;Bolland, S;Long, CA;Wang, R;Su, XZ;, PLoS Pathog. 2016 ,PubMed ID 27716849
P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy ,Jia, YL;Xu, M;Dou, CW;Liu, ZK;Xue, YM;Yao, BW;Ding, LL;Tu, KS;Zheng, X;Liu, QG;, Cell Death Dis 2016 ,PubMed ID 27711074
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy ,Chen, T;Ren, H;Thakur, A;Yang, T;Li, Y;Zhang, S;Wang, T;Chen, M;, DNA Cell Biol. 2016 ,PubMed ID 27661766
Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk ,Averett, C;Bhardwaj, A;Arora, S;Srivastava, SK;Khan, MA;Ahmad, A;Singh, S;Carter, JE;Khushman, M;Singh, AP;, Carcinogenesis 2016 ,PubMed ID 27609457
Mineralocorticoid Receptor (MR) Trans-Activation of Inflammatory AP-1 Signaling: Dependence on DNA Sequence, MR Conformation, and AP-1 Family Member Expression ,Dougherty, EJ;Elinoff, JM;Ferreyra, GA;Hou, A;Cai, R;, The American Society for Biochemistry and Molecular Biology 2016 [pCMV6-Entry]
Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion ,Gaitanos, TN;Koerner, J;Klein, R;, J. Cell Biol 2016 ,PubMed ID 27597758 [pCMV6-Entry]
Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer ,Izrailit, J;Jaiswal, A;Zheng, W;Moran, MF;Reedijk, M;, Oncogene 2016 ,PubMed ID 27593927
Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer ,Xin, B;He, X;Wang, J;Cai, J;Wei, W;Zhang, T;Shen, X;, Pancreatology 2016 ,PubMed ID 27654574
Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay ,Lo, SH;Cheng, KC;Li, YX;Chang, CH;Cheng, JT;Lee, KS;, Drug Des Devel Ther 2016 ,PubMed ID 27578964
CAPS1 Negatively Regulates Hepatocellular Carcinoma Development through Alteration of Exocytosis-Associated Tumor Microenvironment ,Xue, R;Tang, W;Dong, P;Weng, S;Ma, L;Chen, S;Liu, T;Shen, X;Huang, X;Zhang, S;Dong, L;, Int J Mol Sci 2016 ,PubMed ID 27689999
A new NFIA: RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma ,Yde, CW;Sehested, A;Regué, ÀM;Østrup, O;Scheie, D;Nysom, K;Nielsen, FC;Rossing, M;, Cancer Genetics 2016
The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival ,Duggan, SP;Behan, FM;Kirca, M;Zaheer, A;McGarrigle, S;Reynolds, J;FVaz, GM;Senge, M;Kelleher, D;, Science Reports 2016 ,PubMed ID 27586588
E2F1 Orchestrates Transcriptomics and Oxidative Metabolism in Wharton's Jelly-Derived Mesenchymal Stem Cells from Growth-Restricted Infants ,Tan, PY;Chang, CW;Duan, K;Poidinger, M;Ng, KL;Chong, YS;Gluckman, PD;Stünkel, W;, PLoS ONE 2016 ,PubMed ID 27631473
miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9 ,Su, MT;Tsai, PY;Tsai, HL;Chen, YC;Kuo, PL;, Biofactors 2016 ,PubMed ID 27619846
Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome ,Beard, RS;Yang, X;Meegan, JE;Overstreet, JW;Yang, CG;Elliott, JA;Reynolds, JJ;Cha, BJ;Pivetti, CD;Mitchell, DA;Wu, MH;Deschenes, RJ;Yuan, SY;, Nat Commun 2016 ,PubMed ID 27653213
Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression ,Li, A;Zhang, W;Xia, H;Miao, Y;Zhou, H;Zhang, X;Dong, Q;Li, Q;Qiu, X;Wang, E;, Tumour Biol. 2016 ,PubMed ID 27677288
Tubeimoside-1 suppresses breast cancer metastasis through downregulation of CXCR4 chemokine receptor expression ,Peng, Y;Zhong, Y;Li, G;, BMB Rep 2016 ,PubMed ID 27157541 [pCMV6-Entry]
MicroRNA-29a promotes smooth muscle cell differentiation from stem cells by targeting YY1 ,Jin, M;Wu, Y;Wang, Y;Yu, D;Yang, M;Yang, F;Feng, C;Chen, T;, Stem Cell Res 2016 ,PubMed ID 27591939
Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells ,Wilder, CL;Walton, C;Watson, V;Stewart, FA;Johnson, J;Peyton, SR;Payne, CK;Odero-Marah, V;Platt, MO;, Int. J. Biochem. Cell Biol. 2016 ,PubMed ID 27592448
ZNRF1 can inhibit proliferation and stemness properties of leukemia NB4 cells ,Zhao, Y;Li, T;Zhao, L;Wang, J;Shang, Z;Huang, W;Zhou, J;, Animal Cells and Systems 2016
Localization of immunodominant epitopes within the a determinant of hepatitis B surface antigen using monoclonal antibodies ,Golsaz-Shirazi, F;Mohammadi, H;Amiri, MM;Khoshnoodi, J;Kardar, GA;Jeddi-Tehrani, M;Shokri, F;, Arch. Virol. 2016 ,PubMed ID 27439498
COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation ,Pérez-Pérez, R;Lobo-Jarne, T;Milenkovic, D;Mourier, A;Bratic, A;García-Bartolomé, A;Fernández-Vizarra, E;Cadenas, S;Delmiro, A;García-Consuegra, I;Arenas, J;Martín, MA;Larsson, NG;Ugalde, C;, Cell Reports 2016 ,PubMed ID 27545886
Interleukin-13 stimulates MUC5AC expression via a STAT6-TMEM16A-ERK1/2 pathway in human airway epithelial cells ,Qin, Y;Jiang, Y;Sheikh, AS;Shen, S;Liu, J;Jiang, D;, Int. Immunopharmacol. 2016 ,PubMed ID 27588910
The AKAP GSKIP regulates beta-catenin through both its interactions with PKA and GSK3beta ,Dema, A;Schroeter, MF;Perets, E;Skroblin, P;Moutty, MC;Deak, VA;Birchmeier, W;Klussmann, E;, J. Biol. Chem. 2016 ,PubMed ID 27484798
Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression ,Chung, DW;Frausto, RF;Chiu, S;Lin, BR;Aldave, AJ;, Invest. Ophthalmol. Vis. Sci. 2016 ,PubMed ID 27537263
DCLK1 is up-regulated and associated with metastasis and prognosis in colorectal cancer ,Gao, T;Wang, M;Xu, L;Wen, T;Liu, J;An, G;, J. Cancer Res. Clin. Oncol. 2016 ,PubMed ID 27520310
TGF-ß induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype ,Zhang, F;Wang, H;Wang, X;Jiang, G;Liu, H;Zhang, G;Wang, H;Fang, R;Bu, X;Cai, S;Du, J;, Oncotarget 2016 ,PubMed ID 27418133 [pCMV6-Entry]
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease ,Simile, MM;Latte, G;Demartis, MI;Brozzetti, S;Calvisi, DF;Porcu, A;Feo, CF;Seddaiu, MA;Daino, L;Berasain, C;Tomasi, ML;Avila, MA;Feo, F;Pascale, RM;, Oncotarget 2016 ,PubMed ID 27359056 [pCMV6-Entry]
Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene ,Mascarenhas, JB;Tchourbanov, AY;Fan, H;Danilov, SM;Wang, T;Garcia, JG;, Am. J. Respir. Cell Mol. Biol. 2016 ,PubMed ID 27529643
Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas ,Vallois, D;Dobay, MP;Morin, RD;Lemonnier, F;Missiaglia, E;Juilland, M;Iwaszkiewicz, J;Fataccioli, V;Bisig, B;Roberti, A;Grewal, J;Bruneau, J;Fabiani, B;Martin, A;Bonnet, C;Michielin, O;Jais, JP;Figeac, M;Bernard, OA;Delorenzi, M;Haioun, C;Tournilhac, O;Thome, M;Gascoyne, RD;Gaulard, P;de Leval, L;, Blood 2016 ,PubMed ID 27369867
TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis ,Hsieh, J;Koseki, M;Molusky, MM;Yakushiji, E;Ichi, I;Westerterp, M;Iqbal, J;Chan, RB;Abramowicz, S;Tascau, L;Takiguchi, S;Yamashita, S;Welch, CL;Di Paolo, G;Hussain, MM;Lefkowitch, JH;Rader, DJ;Tall, AR;, Nature 2016 ,PubMed ID 27383786
Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells ,Lee, JG;Takahama, S;Zhang, G;Tomarev, SI;Ye, Y;, Nat. Cell Biol. Jul 2016 ,PubMed ID 27295555
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer ,Ahmad, I;Mui, E;Galbraith, L;Patel, R;Tan, EH;Salji, M;Rust, AG;Repiscak, P;Hedley, A;Markert, E;Loveridge, C;van der Weyden, L;Edwards, J;Sansom, OJ;Adams, DJ;Leung, HY;, Proc. Natl. Acad. Sci. U.S.A. 2016 ,PubMed ID 27357679
Activation of AKT negatively regulates the pro-apoptotic function of death-associated protein kinase 3 (DAPK3) in prostate cancer ,Das, TP;Suman, S;Papu John, AM;Pal, D;Edwards, A;Alatassi, H;Ankem, MK;Damodaran, C;, Cancer Lett. Jul 2016 ,PubMed ID 27126362
BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent Manner ,Yamamoto, H;Watanabe, Y;Oikawa, R;Morita, R;Yoshida, Y;Maehata, T;Yasuda, H;Itoh, F;, Clin Transl Gastroenterol 2016 ,PubMed ID 27441821
Mitochondrial Peroxiredoxin-3 protects against hyperglycemia induced myocardial damage in Diabetic cardiomyopathy ,Arkat, S;Umbarkar, P;Singh, S;Sitasawad, SL;, Free Radic. Biol. Med. 2016 ,PubMed ID 27393003
Fibroblast Growth Factor 12 Is a Novel Regulator ofVascular Smooth Muscle Cell Plasticity and Fate ,Song, SH;Kim, K;Jo, EK;Kim, YW;Kwon, JS;Bae, SS;Sung, JH;Park, SG;Kim, JT;Suh, W;, Basic Sciences 2016
The mitochondrial ubiquitin ligase plays an anti-apoptotic role in cardiomyocytes by regulating mitochondrial fission ,Wang, J;Aung, LH;Prabhakar, BS;Li, P;, J. Cell. Mol. Med. 2016 ,PubMed ID 27444773
TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-ß1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling ,Xiong, F;Li, X;Yang, Z;Wang, Y;Gong, W;Huang, J;Chen, C;Liu, P;Huang, H;, Endocrine 2016 ,PubMed ID 27470217
Age-Associated Up-Regulation of EGR1 Promotes Granulosa Cell Apoptosis during Follicle Atresia in Mice through the NF-?B Pathway ,Yuan, S;Wen, J;Cheng, J;Shen, W;Zhou, S;Yan, W;Shen, L;Luo, A;Wang, S;, Cell Cycle 2016 ,PubMed ID 27436181
Coiled-coil domain-containing protein 8 inhibits the invasiveness and migration of non-small cell lung cancer cells ,Jiang, GY;Zhang, XP;Zhang, Y;Xu, HT;Wang, L;Li, QC;Wang, EH;, Hum. Pathol. Jun 2016 ,PubMed ID 27342910
Ring finger protein 43 expression is associated with genetic alteration status and poor prognosis among patients with intrahepatic cholangiocarcinoma ,Talabnin, C;Janthavon, P;Thongsom, S;Suginta, W;Talabnin, K;Wongkham, S;, Hum. Pathol. 2016 ,PubMed ID 26980022 [pCMV6-Entry]
Hypoxia-induced epithelial-mesenchymal transition is regulated by phosphorylation of GSK3-ß via PI3K/Akt signaling in oral squamous cell carcinoma ,Kaneko, T;DDS, ;PhD, ;Dehari, H;DDS, ;PhD, ;Sasaki, T;DDS, ;PhD, ;Igarashi, T;DDS, ;PhD, ;Ogi, K;DDS, ;PhD, ;Okamoto, J;DDS, ;Kawata, M;DDS, ;Kobayashi, J;DDS, ;PhD, ;Miyazaki, A;DDS, ;PhD, ;Nakamori, K;DDS, ;PhD, ;Hiratsuka, H;DDS, ;PhD, ;, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Jun 2016
Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation ,Chang, JW;Jung, SN;Kim, JH;Shim, GA;Park, HS;Liu, L;Kim, JM;Park, J;Koo, BS;, Sci Rep Jun 2016 ,PubMed ID 27328758
Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription ,Nawaz, Z;Patil, V;Arora, A;Hegde, AS;Arivazhagan, A;Santosh, V;Somasundaram, K;, Sci Rep Jun 2016 ,PubMed ID 27291091
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine ,Song, G;Napoli, E;Wong, S;Hagerman, R;Liu, S;Tassone, F;Giulivi, C;, Mol. Med. 2016 ,PubMed ID 27385396
Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor ,Nakamura, T;Ramos-Álvarez, I;Iordanskaia, T;Moreno, P;Mantey, SA;Jensen, RT;, Biochem. Pharmacol. Jun 2016 ,PubMed ID 27346274
CACNA1H(M1549V) mutant calcium channel causes autonomous aldosterone production in HAC15 cells and is inhibited by Mibefradil ,Reimer, EN;Walenda, G;Seidel, E;Scholl, UI;, Endocrinology Jun 2016 ,PubMed ID 27258646
IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment ,Zheng, X;Xu, M;Yao, B;Wang, C;Jia, Y;Liu, Q;, Cell. Signal. Jun 2016 ,PubMed ID 27297362
The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination ,Laitman, BM;Asp, L;Mariani, JN;Zhang, J;Liu, J;Sawai, S;Chapouly, C;Horng, S;Kramer, EG;Mitiku, N;Loo, H;Burlant, N;Pedre, X;Hara, Y;Nudelman, G;Zaslavsky, E;Lee, YM;Braun, DA;Lu, QR;Narla, G;Raine, CS;Friedman, SL;Casaccia, P;John, GR;, PLoS Biol. May 2016 ,PubMed ID 27213272
Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene ,Vodo, D;Sarig, O;Geller, S;Ben-Asher, E;Olender, T;Bochner, R;Goldberg, I;Nosgorodsky, J;Alkelai, A;Tatarskyy, P;Peled, A;Baum, S;Barzilai, A;Ibrahim, SM;Zillikens, D;Lancet, D;Sprecher, E;, PLoS Genet. May 2016 ,PubMed ID 27148741
NKX6. 3 Is a Transcription Factor for Wnt/ß-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression ,Yoon, JH;Eun, JW;Choi, WS;Kim, O;Nam, SW;Lee, JY;, EBioMedicine May 2016 ,PubMed ID 27333045
BPTF transduces MITF-driven prosurvival signals in melanoma cells ,Dar, AA;Majid, S;Bezrookove, V;Phan, B;Ursu, S;Nosrati, M;De Semir, D;Sagebiel, RW;Miller, JR;Debs, R;Cleaver, JE;Kashani-Sabet, M;, Proc. Natl. Acad. Sci. U.S.A. May 2016 ,PubMed ID 27185926
ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation ,Nunes, J;Zhang, H;Angelopoulos, N;Chhetri, J;Osipo, C;Grothey, A;Stebbing, J;Giamas, G;, Oncotarget 2016 ,PubMed ID 27050377
Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer ,Kan, JY;Yen, MC;Wang, JY;Wu, DC;Chiu, YJ;Ho, YW;Kuo, PL;, Oncotarget 2016 ,PubMed ID 27150059
Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer ,Vorvis, C;Hatziapostolou, M;Mahurkar-Joshi, S;Koutsioumpa, M;Williams, J;Donahue, TR;Poultsides, GA;Eibl, G;Iliopoulos, D;, Am. J. Physiol. Gastrointest. Liver Physiol. May 2016 ,PubMed ID 27151939
Connexin 50 modulates Sox2 expression in spinal-cord-derived ependymal stem/progenitor cells ,Rodriguez-Jimenez, FJ;Alastrue, A;Stojkovic, M;Erceg, S;Moreno-Manzano, V;, Cell Tissue Res. May 2016 ,PubMed ID 27221278
RbAp48, a novel inhibitory factor that regulates the transcription of human immunodeficiency virus type 1 ,Wang, J;Yang, J;Yang, Z;Lu, X;Jin, C;Cheng, L;Wu, N;, Int. J. Mol. Med. May 2016 ,PubMed ID 27222146
Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression ,Dong, P;Ihira, K;Xiong, Y;Watari, H;Hanley, SJ;Yamada, T;Hosaka, M;Kudo, M;Yue, J;Sakuragi, N;, Oncotarget 2016 ,PubMed ID 26934121
RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol ,Mitchel, K;Theusch, E;Cubitt, C;Dosé, AC;Stevens, K;Naidoo, D;Medina, MW;, Circ Cardiovasc Genet Apr 2016 ,PubMed ID 27071970
Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells ,Yang, LJ;Tang, Q;Wu, J;Chen, Y;Zheng, F;Dai, Z;Hann, SS;, J. Exp. Clin. Cancer Res. Apr 2016 ,PubMed ID 27036874
Cell-based and in silico evidence against quercetin and structurally-related flavonols as activators of vitamin D receptor ,Lau, AJ;Politi, R;Yang, G;Chang, TK;, J. Steroid Biochem. Mol. Biol. Apr 2016 ,PubMed ID 27041117
Grp94 Delivers ?-aminobutyric Acid Type A (GABAA) Receptors to Hrd1-Mediatd Endoplasmic Reticulum-Associated Degradation ,Di, XJ;Wang, YJ;Han, DY;Fu, YL;Duerfeldt, AS;Blagg, BS;Mu, TW;, J. Biol. Chem. Mar 2016 ,PubMed ID 26945068
Optimizing a custom tiling microarray for low input detection and identification of unamplified virus targets ,Yu, C;Wales, SQ;Mammel, MK;Hida, K;Kulka, M;, J. Virol. Methods Mar 2016 ,PubMed ID 27033182
Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas ,Kitajima, D;Kasamatsu, A;Nakashima, D;Miyamoto, I;, Journal of Cancer Mar 2016 ,PubMed ID 27053959
Overexpression of microRNA-133b sensitizes non-small cell lung cancer cells to irradiation through the inhibition of glycolysis ,Liu, G;Li, Y;Gao, X;, Oncology Letters Mar 2016 ,PubMed ID 27073574
PARP-1 Represses LXR-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages ,Shrestha, E;Hussein, MA;Savas, JN;Ouimet, M;Barrett, TJ;Leone, S;Yates, JR;Moore, KJ;Fisher, EA;Garabedian, MJ;, J. Biol. Chem. Mar 2016 ,PubMed ID 27026705
Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder ,Keller, MD;Pandey, R;Li, D;Glessner, J;Tian, L;Henrickson, SE;Chinn, IK;Monaco-Shawver, L;Heimall, J;Hou, C;Otieno, FG;Jyonouchi, S;Calabrese, L;van Montfrans, J;Orange, JS;Hakonarson, H;, J. Allergy Clin. Immunol. Mar 2016 ,PubMed ID 27016798
The Angiotensin Receptor-associated Protein Atrap is a Stimulator of the Cardiac Ca2+-ATPase SERCA2a ,Mederle, K;Gess, B;Pluteanu, F;Plackic, J;Tiefenbach, KJ;Grill, A;Kockskämper, J;Castrop, H;, Cardiovasc. Res. Mar 2016 ,PubMed ID 27015675
Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes ,Xiao, W;Sarsour, EH;Wagner, BA;Doskey, CM;Buettner, GR;Domann, FE;Goswami, PC;, Arch. Toxicol 2016 ,PubMed ID 25417049 [pCAMV6-empty]
Oxidized low-density lipoprotein upregulates microRNA-146a via JNK and NF-?B signaling ,Li, Z;Wang, S;Zhao, W;Sun, Z;, Molecular Medicine Reports Feb 2016 ,PubMed ID 26718614 [PS100001]
Involvement of ALAD-20S Proteasome Complexes in Ubiquitination and Acetylation of Proteasomal a2 Subunits ,Schmitt, SM;Neslund-Dudas, C;Shen, M;Cui, C;Mitra, B;Dou, QP;, J. Cell. Biochem 2016 ,PubMed ID 26084403
Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer ,Zhao, H;Yu, H;Martin, TA;Zhang, Y;Chen, G;Jiang, WG;, Int. J. Oncol. Jan 2016 ,PubMed ID 26782073 [PS100001]
The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells ,Lu, W;Su, L;Yu, Z;Zhang, S;Miao, J;, Stem Cells International Jan 2016 [PS100001]
YKL-40/chitinase-3-like protein 1 is associated with poor prognosis and promotes cell growth and migration of cholangiocarcinoma ,Thongsom, S;Chaocharoen, W;Silsirivanit, A;Wongkham, S;Sripa, B;Choe, H;Suginta, W;Talabnin, C;, Tumour Biol. Jan 2016 ,PubMed ID 26781979 [PS100001]
SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response ,Bologna, C;Buonincontri, R;Serra, S;Vaisitti, T;Audrito, V;Brusa, D;Pagnani, A;Coscia, M;D'Arena, G;Mereu, E;Piva, R;Furman, RR;Rossi, D;Gaidano, G;Terhorst, C;Deaglio, S;, J. Clin. Invest. Jan 2016 ,PubMed ID 26619119 [PS100001]
HER2 drives Mucin-like 1 to control proliferation in breast cancer cells ,Conley, SJ;Bosco, EE;Tice, DA;Hollingsworth, RE;Herbst, R;Xiao, Z;, Oncogene Jan 2016 ,PubMed ID 26725324 [PS100001]
Epigenetic regulation of the homeobox gene MSX1 associates with platinum resistant disease in high grade serous epithelial ovarian cancer ,Bonito, NA;Borely, J;Wilhelm-Benartzi, C;Ghaem-Maghami, S;Brown, R;, Clin. Cancer Res. Jan 2016 ,PubMed ID 26763252 [PS100001]
AP-1 is a key regulator of proinflammatory cytokine TNFa-mediated triple-negative breast cancer progression ,Qiao, Y;He, H;Jonsson, P;Sinha, I;Zhao, C;Dahlman-Wright, K;, J. Biol. Chem. Jan 2016 ,PubMed ID 26792858 [PS100001]
NPAS4 Facilitates the Autophagic Clearance of Endogenous Tau in Rat Cortical Neurons ,Fan, W;Long, Y;Lai, Y;Wang, X;Chen, G;Zhu, B;, J. Mol. Neurosci. Dec 2015 ,PubMed ID 26635026 [PS100001]
Prognostic Significance and Functional Role of CEP57 in Prostate Cancer ,Mang, J;Korzeniewski, N;Dietrich, D;Sailer, V;Tolstov, Y;Searcy, S;von Hardenberg, J;Perner, S;Kristiansen, G;Marx, A;Roth, W;Herpel, E;Grüllich, C;Popeneciu, V;Pahernik, S;Hadaschik, B;Hohenfellner, M;Duensing, S;, Transl Oncol Dec 2015 ,PubMed ID 26692530 [PS100001]
Acetyl-CoA carboxylase a promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients ,Wang, MD;Wu, H;Fu, GB;Zhang, HL;Zhou, X;Tang, L;Dong, LW;Qin, CJ;Huang, S;Zhao, LH;Zeng, M;Wu, MC;Yan, HX;Wang, HY;, Hepatology Dec 2015 ,PubMed ID 26698170 [PS100001]
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer ,Hopkins, TG;Mura, M;Al-Ashtal, HA;Lahr, RM;Abd-Latip, N;Sweeney, K;Lu, H;Weir, J;El-Bahrawy, M;Steel, JH;Ghaem-Maghami, S;Aboagye, EO;Berman, AJ;Blagden, SP;, Nucleic Acids Res. Dec 2015 ,PubMed ID 26717985 [PS100001]
The role of HO-1 in protection against lead-induced neurotoxicity ,Li, X;Ye, F;Li, L;Chang, W;Wu, X;Chen, J;, Neurotoxicology Nov 2015 ,PubMed ID 26542248 [PS100001]
Chaperone BAG6 is dispensable for MHC class I antigen processing and presentation ,Bitzer, A;Basler, M;Groettrup, M;, Mol. Immunol. Nov 2015 ,PubMed ID 26598275 [PS100001]
Connexin 50 Expression in Ependymal Stem Progenitor Cells after Spinal Cord Injury Activation ,Rodriguez-Jimenez, FJ;Alastrue-Agudo, A;Stojkovic, M;Erceg, S;Moreno-Manzano, V;, Int J Mol Sci Nov 2015 ,PubMed ID 26561800 [PS100001]
The in vivo disposition and in vitro transmembrane transport of two model radiometabolites of DOTA-conjugated receptor-specific peptides labelled with 177Lu ,Volková, M;Mandíková, J;Bárta, P;, Journal of Labelled Compounds and Radiopharmaceuticals Nov 2015 [PS100001]
Novel myristoylation of the sperm-specific hexokinase 1 isoform regulates its atypical localization ,Kumar, S;Parameswaran, S;Sharma, RK;, Biol Open Nov 2015 ,PubMed ID 26581589 [PS100001]
Autophagy positively regulates DNA damage recognition by nucleotide excision repair ,Qiang, L;Zhao, B;Shah, P;Sample, A;Yang, S;He, YY;, Autophagy Nov 2015 ,PubMed ID 26565512 [PS100001]
A case report of thrombotic microangiopathy without renal involvement carrying two novel mutations in complement-regulator genes ,Peyvandi, F;Rossio, R;Ferrari, B;Lotta, LA;Pontiggia, S;Ghiringhelli Borsa, N;Pizzuti, M;Donadelli, R;Piras, R;Cugno, M;Noris, M;, J. Thromb. Haemost. Nov 2015 ,PubMed ID 26613809 [PS100001]
MCM3AP and POMP Mutations Cause a DNA-Repair and DNA-Damage-Signaling Defect in an Immunodeficient Child ,Gatz, SA;Salles, D;Jacobsen, EM;Dörk, T;Rausch, T;Aydin, S;Surowy, H;Volcic, M;Vogel, W;Debatin, KM;Stütz, AM;Schwarz, K;Pannicke, U;Hess, T;Korbel, JO;Schulz, AS;Schumacher, J;Wiesmüller, L;, Hum. Mutat. Nov 2015 ,PubMed ID 26615982 [PS100001]
SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma ,Yu, Y;Chen, Y;Ma, J;Yu, X;Yu, G;Li, Z;, Tumour Biol. Oct 2015 ,PubMed ID 26490986 [PS100001]
Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells ,Ramos-Álvarez, I;Nakamura, T;Mantey, SA;Moreno, P;Nuche-Berenguer, B;Jensen, RT;, Peptides Oct 2015 ,PubMed ID 26524625 [PS100001]
Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice ,Barati, MT;Powell, DW;Kechavarzi, BD;Isaacs, SM;Zheng, S;Epstein, PN;Cai, L;Coventry, S;Rane, MJ;Klein, JB;, Cell Stress Chaperones Oct 2015 ,PubMed ID 26483256 [PS100001]
Connexin43-containing gap junctions potentiate extracellular Ca(2+)-induced odontoblastic differentiation of human dental pulp stem cells via Erk1/2 ,Li, S;He, H;Zhang, G;Wang, F;Zhang, P;Tan, Y;, Exp. Cell Res. Oct 2015 ,PubMed ID 26376117 [PS100001]
Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3ß-C/EBPß pathway ,Maekawa, T;Hosur, K;Abe, T;Kantarci, A;, NATURE COMMUNICATIONS Sep 2015 ,PubMed ID 26374165 [PS100001]
The RNA-binding protein Musashi 1 stabilizes the onco tachykinin 1 mRNA in breast cancer cells to promote cell growth ,Nahas, GR;Murthy, RG;Patel, SA;Ganta, T;Greco, SJ;Rameshwar, P;, FASEB J. Sep 2015 ,PubMed ID 26373800 [PS100001]
Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells ,Wu, J;Zhao, S;Tang, Q;Zheng, F;Chen, Y;Yang, L;Yang, X;Li, L;Wu, W;Hann, SS;, J. Exp. Clin. Cancer Res. Sep 2015 ,PubMed ID 26362062 [PS100001]
Expression and purification of the surface proteins from Andes Virus ,Beltrán-Ortiz, CE;Starck-Mendez, MF;Fernández, Y;Farnós, O;González, EE;Rivas, CI;Camacho, F;Zuñiga, FA;Toledo, JR;Sánchez, O;, Protein Expr. Purif. Sep 2015 ,PubMed ID 26374989 [PS100001]
Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target ,Asaka, R;Miyamoto, T;Yamada, Y;Ando, H;Mvunta, DH;Kobara, H;Shiozawa, T;, Lab. Invest. Sep 2015 ,PubMed ID 26367491 [PS100001]
LRRC3B is downregulated in non-small-cell lung cancer and inhibits cancer cell proliferation and invasion ,Kan, L;Li, H;Zhang, Y;Wang, J;Niu, H;Jiang, H;Zhang, M;Bai, X;He, P;, Tumour Biol. Aug 2015 ,PubMed ID 26276358 [PS100001]
Overexpression of SPAG9 in human gastric cancer is correlated with poor prognosis ,Miao, ZF;Wang, ZN;Zhao, TT;Xu, YY;Wu, JH;Liu, XY;Xu, H;You, Y;Xu, HM;, Virchows Arch. Aug 2015 ,PubMed ID 26293216 [PS100001]
TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations ,Hua, F;Li, K;Yu, JJ;Lv, XX;Yan, J;Zhang, XW;Sun, W;Lin, H;Shang, S;Wang, F;Cui, B;Mu, R;Huang, B;Jiang, JD;Hu, ZW;, Nat Commun Aug 2015 ,PubMed ID 26268733 [PS100001]
Indoleamine 2,3-dioxygenase 1 in corneal endothelial cells limits herpes simplex virus type 1-induced acquired immune response ,Haruki, T;Miyazaki, D;Inata, K;Sasaki, SI;Yamamoto, Y;Kandori, M;Yakura, K;Noguchi, Y;Touge, C;Ishikura, R;Touge, H;Yamagami, S;Inoue, Y;, Br J Ophthalmol Jul 2015 ,PubMed ID 26142400 [PS100001]
miR-9 promotes cell proliferation and inhibits apoptosis by targeting LASS2 in bladder cancer ,Wang, H;Zhang, W;Zuo, Y;Ding, M;Ke, C;Yan, R;Zhan, H;Liu, J;Wang, J;, Tumour Biol. Jul 2015 ,PubMed ID 26150338 [PS100001]
A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia ,Mou, L;Zhang, Q;Diao, R;Cai, Z;Gui, Y;, Reprod. Biol. Endocrinol. Jul 2015 ,PubMed ID 26223869 [PS100001]
Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis ,Papageorgis, P;Ozturk, S;Lambert, AW;Neophytou, CM;Tzatsos, A;Wong, CK;Thiagalingam, S;Constantinou, AI;, Breast Cancer Res. Jul 2015 ,PubMed ID 26208975 [PS100001]
L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated a1(D219N) Subunits of GABAA Receptors ,Han, DY;Guan, BJ;Wang, YJ;Hatzoglou, M;Mu, TW;, ACS Chem. Biol. Jul 2015 ,PubMed ID 26168288 [PS100001]
Nuclear matrix protein Matrin 3 is a regulator of ZAP-mediated retroviral restriction ,Erazo, A;Goff, SP;, Retrovirology Jul 2015 ,PubMed ID 26129669 [PS100001]
Enhanced Human Decidual Cell-Expressed FKBP51 May Promote Labor-Related Functional Progesterone Withdrawal ,Schatz, F;Guzeloglu-Kayisli, O;Basar, M;Buchwalder, LF;Ocak, N;Guzel, E;Guller, S;Semerci, N;Kayisli, UA;Lockwood, CJ;, Am. J. Pathol. Jul 2015 ,PubMed ID 26207680 [PS100001]
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization ,Fumagalli, M;Bonfanti, E;Daniele, S;Zappelli, E;Lecca, D;Martini, C;Trincavelli, ML;Abbracchio, MP;, Glia Jul 2015 ,PubMed ID 26228571 [PS100001]
Claudin-3 is required for modulation of paracellular permeability by TNF-a through ERK1/2/slug signaling axis in submandibular gland ,Mei, M;Xiang, RL;Cong, X;Zhang, Y;Li, J;Yi, X;Park, K;Han, JY;Wu, LL;Yu, GY;, Cell. Signal. Jul 2015 ,PubMed ID 26148935 [PS100001]
3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease ,Lau, AJ;Chang, TK;, Pharmacol. Res. Jul 2015 ,PubMed ID 26238175 [PS100001]
URI expression in cervical cancer cells is associated with higher invasion capacity and resistance to cisplatin ,Gu, J;Liang, Y;Qiao, L;Lu, Y;Hu, X;Luo, D;Li, N;Zhang, L;Chen, Y;Du, J;Zheng, Q;, Am J Cancer Res Jun 2015 ,PubMed ID 26101702 [PS100001]
ANKRD1 modulates inflammatory responses IN C2C12 myoblasts through feedback inhibition OF NF-?B signaling activity ,Liu, XH;Bauman, WA;Cardozo, C;, Biochem. Biophys. Res. Commun. Jun 2015 ,PubMed ID 26102030 [PS100001]
Increased levels of soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death in human lung epithelial cells ,Blake, DJ;Reese, CM;Garcia, M;Dahlmann, EA;Dean, A;, Toxicol In Vitro Jun 2015 ,PubMed ID 26100223 [PS100001]
A novel biomarker C6orf106 promotes the malignant progression of breast cancer ,Jiang, G;Zhang, X;Zhang, Y;Wang, L;Fan, C;Xu, H;Miao, Y;Wang, E;, Tumour Biol. May 2015 ,PubMed ID 25953261 [PS100001]
ErbB2-intronic microRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signaling ,Schmitt, DC;Madeira da Silva, L;Zhang, W;Liu, Z;Arora, R;Lim, S;Schuler, AM;McClellan, S;Andrews, JF;Kahn, AG;Zhou, M;Ahn, EY;Tan, M;, Cell Death Dis May 2015 ,PubMed ID 25950472 [PS100001]
Soluble receptor for advanced glycation end products inhibits disease progression in autosomal dominant polycystic kidney disease by down-regulating cell proliferation ,Lee, EJ;Park, EY;Mun, H;Chang, E;Ko, JY;Kim, DY;Park, JH;, FASEB J. May 2015 ,PubMed ID 25934702 [PS100001]
Eosinophils Contribute to Early Clearance of Pneumocystis murina Infection ,Eddens, T;Elsegeiny, W;Nelson, MP;Horne, W;Campfield, BT;Steele, C;Kolls, JK;, J. Immunol. May 2015 ,PubMed ID 25994969 [PS100001]
Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer ,Saavedra, K;Valbuena, J;Olivares, W;Marchant, MJ;Rodríguez, A;Torres-Estay, V;Carrasco-Avino, G;Guzmán, L;Aguayo, F;Roa, JC;Corvalán, AH;, PLoS ONE May 2015 ,PubMed ID 25954972 [PS100001]
Role of Oxidative Stress Mediated by Glutathione-S-transferase in Thiopurines' Toxic Effects ,Pelin, M;De Iudicibus, S;Fusco, L;Taboga, E;Pellizzari, G;Lagatolla, C;Martelossi, S;Ventura, A;Decorti, G;Stocco, G;, Chem. Res. Toxicol. May 2015 ,PubMed ID 25928802 [PS100001]
Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Ga12 ,Wang, Z;Guan, W;Han, Y;Ren, H;Tang, X;Zhang, H;Liu, Y;Fu, J;He, D;Asico, LD;Jose, PA;Zhou, L;Chen, L;Zeng, C;, Transplantation May 2015 ,PubMed ID 25989500 [PS100001]
Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma ,Chang, I;Mitsui, Y;Fukuhara, S;Gill, A;Wong, DK;Yamamura, S;Shahryari, V;Tabatabai, ZL;Dahiya, R;Shin, DM;Tanaka, Y;, Oncotarget Apr 2015 ,PubMed ID 25860934 [PS100001]
Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression ,Tsuru, A;Setoguchi, T;Matsunoshita, Y;Nagao-Kitamoto, H;Nagano, S;Yokouchi, M;Maeda, S;Ishidou, Y;Yamamoto, T;Komiya, S;, Br. J. Cancer Apr 2015 ,PubMed ID 25742474 [PS100001]
CD11b(+) myeloid cells support hepatic metastasis through downregulation of Angiopoietin-like 7 in cancer cells ,Lim, SY;Gordon-Weeks, A;Allen, D;Kersemans, V;Beech, J;Smart, S;Muschel, RJ;, Hepatology Apr 2015 ,PubMed ID 25854806 [PS100001]
Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways ,Mitsui, Y;Hirata, H;Arichi, N;Hiraki, M;Yasumoto, H;Chang, I;Fukuhara, S;Yamamura, S;Shahryari, V;Deng, G;Saini, S;Majid, S;Dahiya, R;Tanaka, Y;Shiina, H;, Oncotarget Apr 2015 ,PubMed ID 25797254 [PS100001]
Apolipoprotein D internalization is a basigin dependent mechanism ,Najyb, O;Brissette, L;Rassart, E;, J. Biol. Chem. Apr 2015 ,PubMed ID 25918162 [PS100001]
Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma ,Gai, X;Tu, K;Li, C;Lu, Z;Roberts, LR;Zheng, X;, Cell Death Dis Apr 2015 ,PubMed ID 25855960 [PS100001]
VAV3 Oncogene Expression in Colorectal Cancer: Clinical Aspects and Functional Characterization ,Uen, YH;Fang, CL;Hseu, YC;Shen, PC;Yang, HL;Wen, KS;Hung, ST;Wang, LH;Lin, KY;, Sci Rep Mar 2015 ,PubMed ID 25791293 [PS100001]
Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses ,Malaguarnera, R;Nicolosi, ML;Sacco, A;Morcavallo, A;Vella, V;Voci, C;Spatuzza, M;Xu, SQ;Iozzo, RV;Vigneri, R;Morrione, A;Belfiore, A;, Oncotarget Mar 2015 ,PubMed ID 25840417 [PS100001]
CXCR3 Signaling in BRAFWT Melanoma Increases IL-8 Expression and Tumorigenicity ,Jenkins, MH;Brinckerhoff, CE;Mullins, DW;, PLoS ONE Mar 2015 ,PubMed ID 25798946 [PS100001]
CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-?B pathway in multidrug-resistant glioblastoma cells in vitro ,Xi, G;Hayes, E;Lewis, R;Ichi, S;Mania-Farnell, B;Shim, K;Takao, T;Allender, E;Mayanil, CS;Tomita, T;, Oncogene Mar 2015 ,PubMed ID 25823028 [PS100001]
TMEM16A mediates the hypersecretion of mucus induced by Interleukin-13 ,Lin, J;Jiang, Y;Li, L;Liu, Y;Tang, H;Jiang, D;, Exp. Cell Res. Mar 2015 ,PubMed ID 25770012 [PS100001]
The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells ,Ouazia, D;Levros, LC;Rassart, É;Desrosiers, RR;, Neuroscience Mar 2015 ,PubMed ID 25800307 [PS100001]
Transcription Factor Brn-3b Overexpression Enhances Neurite Outgrowth in PC12 Cells Under Condition of Hypoxia ,Phatak, NR;Stankowska, DL;Krishnamoorthy, RR;, Cell. Mol. Neurobiol. Mar 2015 ,PubMed ID 25786379 [PS100001]
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn ,Zhang, X;Miao, Y;Yu, X;Zhang, Y;Jiang, G;Liu, Y;Yu, J;Han, Q;Zhao, H;Wang, E;, Tumour Biol. Mar 2015 ,PubMed ID 25736925 [PS100001]
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia ,Noetzli, L;Lo, RW;Lee-Sherick, AB;Callaghan, M;Noris, P;Savoia, A;Rajpurkar, M;Jones, K;Gowan, K;Balduini, CL;Pecci, A;Gnan, C;De Rocco, D;Doubek, M;Li, L;Lu, L;Leung, R;Landolt-Marticorena, C;Hunger, S;Heller, P;Gutierrez-Hartmann, A;Xiayuan, L;Pluthero, FG;Rowley, JW;Weyrich, AS;Kahr, WH;Porter, CC;Di Paola, J;, Nat. Genet. Mar 2015 ,PubMed ID 25807284 [PS100001]
Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer ,Hiraki, M;Nishimura, J;Takahashi, H;Wu, X;Takahashi, Y;Miyo, M;Nishida, N;Uemura, M;Hata, T;Takemasa, I;Mizushima, T;Soh, JW;Doki, Y;Mori, M;Yamamoto, H;, Mol Ther Nucleic Acids Mar 2015 ,PubMed ID 25756961 [PS100001]
Hypoxia up-regulates SERPINB3 through HIF-2a in human liver cancer cells ,Cannito, S;Turato, C;Paternostro, C;Biasiolo, A;Colombatto, S;Cambieri, I;Quarta, S;Novo, E;Morello, E;Villano, G;Fasolato, S;Musso, T;David, E;Tusa, I;Rovida, E;Autelli, R;Smedile, A;Cillo, U;Pontisso, P;Parola, M;, Oncotarget Feb 2015 ,PubMed ID 25544768 [PS100001]
LRAT Overexpression Diminishes Intracellular Levels of Biologically Active Retinoids and Reduces Retinoid Antitumor Efficacy in the Murine Melanoma B16F10 Cell Line ,Amann, PM;Czaja, K;Bazhin, AV;Rühl, R;Eichmüller, SB;Merk, HF;Baron, JM;, Skin Pharmacol Physiol Feb 2015 ,PubMed ID 25721651 [PS100001]
TRIM24 is upregulated in human gastric cancer and promotes gastric cancer cell growth and chemoresistance ,Miao, ZF;Wang, ZN;Zhao, TT;Xu, YY;Wu, JH;Liu, XY;Xu, H;You, Y;Xu, HM;, Virchows Arch. Feb 2015 ,PubMed ID 25724180 [PS100001]
The Rheumatoid Arthritis Risk Gene, LBH, Regulates Growth in Fibroblast-like Synoviocytes ,Ekwall, AK;Whitaker, JW;Hammaker, D;Bugbee, W;Wang, W;Firestein, GS;, Arthritis & rheumatology Feb 2015 ,PubMed ID 25707478 [PS100001]
Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma ,Zhao, X;Parpart, S;Takai, A;Roessler, S;Budhu, A;Yu, Z;Blank, M;Zhang, YE;Jia, HL;Ye, QH;Qin, LX;Tang, ZY;Thorgeirsson, SS;Wang, XW;, Oncogene Jan 2015 ,PubMed ID 25597408 [PS100001]
Chronic Lymphocytic Leukemia Cells Express CD38 in Response to Th1 Cell-Derived IFN-? by a T-bet-Dependent Mechanism ,Bürgler, S;Gimeno, A;Parente-Ribes, A;Wang, D;Os, A;Devereux, S;Jebsen, P;Bogen, B;Tjønnfjord, GE;Munthe, LA;, J. Immunol. Jan 2015 ,PubMed ID 25505279 [PS100001]
Histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing IL-6 and TNF-a production ,Xu, G;Liu, G;Xiong, S;Liu, H;Chen, X;Zheng, B;, J. Biol. Chem. Jan 2015 ,PubMed ID 25583990 [PS100001]
CD44 Regulates Pancreatic Cancer Invasion through MT1-MMP ,Jiang, W;Zhang, Y;Kane, KT;Collins, MA;Simeone, DM;di Magliano, MP;Nguyen, KT;, Mol. Cancer Res. Jan 2015 ,PubMed ID 25566991 [PS100001]
EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer ,Kim, SJ;Tae, CH;Hong, SN;Min, BH;Chang, DK;Rhee, PL;Kim, JJ;Kim, HC;Kim, DH;Kim, YH;, Mol. Carcinog. Jan 2015 ,PubMed ID 25620232 [PS100001]
Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity ,Taniuchi, K;Furihata, M;Hanazaki, K;Iwasaki, S;Tanaka, K;Shimizu, T;Saito, M;Saibara, T;, Pancreas Dec 2014 ,PubMed ID 25426613 [PS100001]
Overexpression of Numb suppresses growth, migration, and invasion of human clear cell renal cell carcinoma cells ,Sima, J;Zhang, B;Yu, Y;Sima, X;Mao, Y;, Tumour Biol. Dec 2014 ,PubMed ID 25480416 [PS100001]
KIF20A-Mediated RNA Granule Transport System Promotes the Invasiveness of Pancreatic Cancer Cells ,Taniuchi, K;Furihata, M;Saibara, T;, Neoplasia Dec 2014 ,PubMed ID 25499221 [PS100001]
DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia ,Rampal, R;Alkalin, A;Madzo, J;Vasanthakumar, A;Pronier, E;Patel, J;Li, Y;Ahn, J;Abdel-Wahab, O;Shih, A;Lu, C;Ward, PS;Tsai, JJ;Hricik, T;Tosello, V;Tallman, JE;Zhao, X;Daniels, D;Dai, Q;Ciminio, L;Aifantis, I;He, C;Fuks, F;Tallman, MS;Ferrando, A;Nimer, S;Paietta, E;Thompson, CB;Licht, JD;Mason, CE;Godley, LA;Melnick, A;Figueroa, ME;Levine, RL;, Cell Rep Dec 2014 ,PubMed ID 25482556 [PS100001]
Salt-inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer ,Bon, H;Wadhwa, K;Schreiner, A;Osborne, M;Carroll, T;Ramos-Montoya, A;Ross-Adams, H;Visser, M;Hoffmann, R;Ahmed, AA;Neal, DE;Mills, IG;, Mol. Cancer Res. Dec 2014 ,PubMed ID 25548099 [PS100001]
PROX1 Gene is Differentially Expressed in Oral Cancer and Reduces Cellular Proliferation ,Rodrigues, MF;de Oliveira Rodini, C;de Aquino Xavier, FC;Paiva, KB;Severino, P;Moyses, RA;López, RM;DeCicco, R;Rocha, LA;Carvalho, MB;Tajara, EH;Nunes, FD;, Medicine (Baltimore) Dec 2014 ,PubMed ID 25526434 [PS100001]
Mutations Affecting the BHLHA9 DNA-Binding Domain Cause MSSD, Mesoaxial Synostotic Syndactyly with Phalangeal Reduction, Malik-Percin Type ,Malik, S;Percin, FE;Bornholdt, D;Albrecht, B;, American Journal of Human Genetics Nov 2014 [cDNA Library]
TD-19, an Erlotinib Derivative, Induces Epidermal Growth Factor Receptor Wild-Type Nonsmall-Cell Lung Cancer Apoptosis through CIP2A-Mediated Pathway ,Chao, TT;Wang, CY;Lai, CC;Chen, YL;Tsai, YT;Chen, PT;Lin, HI;Huang, YC;Shiau, CW;Yu, CJ;Chen, KF;, J. Pharmacol. Exp. Ther. Nov 2014 ,PubMed ID 25187431 [PS100001]
A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells ,Thrane, S;Pedersen, AM;Thomsen, MB;Kirkegaard, T;Rasmussen, BB;Duun-Henriksen, AK;Lænkholm, AV;Bak, M;Lykkesfeldt, AE;Yde, CW;, Oncogene Nov 2014 ,PubMed ID 25362855 [PS100001]
A novel E2F/Sphingosine kinase 1 axis regulates anthracycline response in squamous cell carcinoma ,Hazar-Rethinam, M;Merida de Long, L;Gannon, O;Topkas, E;Boros, S;Vargas, AC;Dzienis, M;Mukhopadhyay, P;Simpson, F;Endo-Munoz, LB;Saunders, NA;, Clin. Cancer Res. Nov 2014 ,PubMed ID 25411162 [PS100001]
Combining VCP Inhibition and SAHA Treatment Additively Enhances the Folding, Trafficking, and Function of Epilepsy-Associated GABAA Receptors ,Han, DY;Di, XJ;Fu, YL;Mu, TW;, J. Biol. Chem. Nov 2014 ,PubMed ID 25406314 [cDNA Library]
Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion ,Nagao-Kitamoto, H;Setoguchi, T;Kitamoto, S;Nakamura, S;Tsuru, A;Nagata, M;Nagano, S;Ishidou, Y;Yokouchi, M;Kitajima, S;Yoshioka, T;Maeda, S;Yonezawa, S;Komiya, S;, Cancer Lett. Nov 2014 ,PubMed ID 25449781 [shRNA]
The involvement of selected membrane transport mechanisms in the cellular uptake of 177Lu-labeled bombesin, somatostatin and gastrin analogues ,Volková, M;Mandíková, J;Láznícková, A;, Nuclear Medicine and Biology Sep 2014 [SC400392]
Restored immunosuppressive effect of mesenchymal stem cells on B cells after OAZ downregulation in patients with systemic lupus erythematosus ,Feng, X;Che, N;Liu, Y;Chen, H;Wang, D;Li, X;Chen, W;Ma, X;Hua, B;Gao, X;Tsao, BP;Sun, L;, Arthritis & rheumatology Sep 2014 ,PubMed ID 25219468 [PS100062]
The LIMP-2/SCARB2 binding motif on acid ß-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases ,Liou, B;Haffey, WD;Greis, KD;Grabowski, GA;, J. Biol. Chem. Sep 2014 ,PubMed ID 25202012 [PS100042]
HMGA2-mediated epigenetic regulation of Gata6 controls epithelial canonical WNT signaling during lung development and homeostasis ,Singh, I;, Thesis Sep 2014 [PS100010]
ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit ,Circuit, PCS;, Cancer Res Jun 2014 ,PubMed ID 24934811 [PS100001]
DUF1220 protein domains drive proliferation in human neural stem cells and are associated with increased cortical volume in anthropoid primates ,Keeney, JG;Davis, JM;Siegenthaler, J;Post, MD;Nielsen, BS;Hopkins, WD;Sikela, JM;, Brain Struct Funct Jun 2014 ,PubMed ID 24957859 [PS100001]
The renal handling of amphotericin B and amphotericin B/deoxycholate and potential renal drug-drug interactions with selected antivirals ,Trejtnar, F;Mandíková, J;Kocíncová, J;Volková, M;, Antimicrob. Agents Chemother. Jun 2014 ,PubMed ID 24957831 [HPRT502]
Overexpression of alpha (1,6) fucosyltransferase associated with aggressive prostate cancer ,Wang, X;Chen, J;Li, QK;Peskoe, SB;Zhang, B;Choi, C;Platz, EA;Zhang, H;, Glycobiology Jun 2014 ,PubMed ID 24906821 [CH1010]
SOD3 Acts as a Tumor Suppressor in PC-3 Prostate Cancer Cells via Hydrogen Peroxide Accumulation ,KIM, J;MIZOKAMI, A;SHIN, M;IZUMI, K;, Anticancer Research Jun 2014 [PS100001]
TMEM16A protein attenuates lipopolysaccharide-mediated inflammatory response of human lung epithelial cell line A549 ,Zhang, A;Yan, X;Li, H;Gu, Z;Zhang, P;Zhang, H;Li, Y;Yu, H;, Exp. Lung Res. Jun 2014 ,PubMed ID 24784799 [Tissues]
Kaiso Interacts with p120-Catenin to Regulate β-Catenin Expression at the Transcriptional Level ,Liu, Y;Dong, QZ;Wang, S;Xu, HT;Miao, Y;Wang, L;Wang, EH;, PLoS ONE, Feb 2014. ,PubMed ID 24498333 [SC305326]
Caracterização funcional de HTRA1 em linhagens celulares HPV positiva e HPV negativa ,Stuqui, B;, Thesis Jan 2014 [RG202222]
DDIAS promotes invasion and proliferation of non-small cell lung cancer and predicts poor survival of lung cancer patients ,Liu, N;Zhang, X;Zhou, H;Cai, L;Li, A;Miao, Y;Li, Q;Qiu, X;Wang, E;, Int J Clin Exp Pathol 2014 ,PubMed ID 24419413 [pCMV6-Entry]
Deletion of the Activated Protein-1 Transcription Factor JunD Induces Oxidative Stress and Accelerates Age-Related Endothelial Dysfunction ,Francesco Paneni, MD;Sylvie Briand, MD; Enrico Perna;Alexander Akhmedov, MD; Lucia Rohrer;Giovanni G. Camici, MD; Fatima Mechta-Grigoriou;Massimo Volpe, MD; Francesco Cosentino;, Vascular Medicine Aug 2013 [TF302060]
Trafficking of the Transcription Factor Nrf2 to Promyelocytic Leukemia-Nuclear Bodies: IMPLICATIONS FOR DEGRADATION OF NRF2 IN THE NUCLEUS* ,Flores, J;Ifeanyi, J;McIntosh, TSW;Malloy, AMT;, The American Society for Biochemistry and Molecular Biology Mar 2013 [BCRT101]

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Product Manuals
TrueORF and PrecisionShuttle cloning vectors Application Guide
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ORF PrecisionShuttle Cloning Vector

Resources

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Video Tutorial: Clone Selection Guide Product Video: Why Should You Choose TrueORF GOLD shRNA Selection Guide Protocol: Lentivirus packaging CRISPR Knockout kit manual CRISPR vector manual CRISPR Trangene Knockin at AAVS1 and ROSA26 loci manual CRISPR activation (CRISPRa) and CRISPR interference (CRISPRi) manual

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