M-CSF (CSF1) (NM_172212) Human Recombinant Protein

SKU
TP723739
Purified recombinant protein of Human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4
  $290.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Human M-CSF, the region of Glu33-Ser190, from gene Accession# NM_172212.2
Tag Tag Free
Predicted MW 20.6 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity The ED50 is 0.5 - 2 ng/ml, corresponding to a specific activity of 0.5 - 2 x 10^6 units/mg, determined by M-NFS60 cell proliferation induced by human M-CSF in a dose dependent manner.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_757351
Locus ID 1435
UniProt ID P09603
Cytogenetics 1p13.3
RefSeq Size 2772
RefSeq ORF 1662
Synonyms CSF-1; MCSF
Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2011
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage
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LY424534 Transient overexpression lysate of colony stimulating factor 1 (macrophage) (CSF1), transcript variant 1 (as WB positive control) 100 ug
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LY430359 Transient overexpression lysate of colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4 (as WB positive control) 100 ug
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TP317104 Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 1, 20 µg 20 ug
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TP317172 Recombinant protein of human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 3, 20 µg 20 ug
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