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Mcam Mouse Gene Knockout Kit (CRISPR)

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SKU
KN309859LP
Mcam - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Mcam or BC026985"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Mcam
Locus ID 84004
Components

KN309859G1, Mcam gRNA vector 1 in pCas-Guide CRISPR vector

KN309859G2, Mcam gRNA vector 2 in pCas-Guide CRISPR vector

KN309859LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_023061, NM_001359530
UniProt ID Q8R2Y2
Synonyms 1-gicerin; AV025631; CD146; CD149; Muc18; s-endo; s-gicerin
Summary Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA211277 Mcam CRISPRa kit - CRISPR gene activation of mouse melanoma cell adhesion molecule 1 kit
$1,657.00
KN309859 Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859BN Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859RB Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN509859 Mcam - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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