OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Mcam Mouse Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN309859
Mcam - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA389740 CD146 Rabbit pAb
100 ul
$410.00
MR209740 Mcam (Myc-DDK-tagged) - Mouse melanoma cell adhesion molecule (Mcam)
10 ug
$289.00 $604.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "Mcam or BC026985"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol Mcam
Locus ID 84004
Components

KN309859G1, Mcam gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: CAACATAAAGAACTCACCCG

KN309859G2, Mcam gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: TGATCTCCGGTACACTCAGG

KN309859D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

AAGGCACCGT TTCCAACTCT CCCGCCCCCT TGCAGGCACC CCTAGGTCTG TGGGACCTGG CACAGTTCTT CCTCCAAGGC TGCCAGGCCA GCGAAGACTC TGGAACAGTG CCAAGCCGGC AGCCGCCGCA GTGAAGCGGT CATTCCAGAA GGCGACCAGG GCCAGCTCCA TGCCTCCACA GCAGGGTAGA GGAACCTGAC TGAGAGTCCT CTATCAGGGA TACCTCTCTG TTGCTCCTCT GCTAGAGGGT CCCCGCTAGT AGTGGACAAA CCTGAGCGAG CGCTGCTACT GCGTCCAAGA GTCTACAGCG ACCGGGCCAG CTTCTGCCGC CTCGGCCAGT CATTCGAGCC CCAGGACACC TGTCATTGCT CCTTCAACCT TTCCAAGCCA GAAAACGGGA GTTAGCCTCT AGGCCTGGAT CGGGGAGCAG CAGCTCGCAG CCAGCGCGCC GGGGGCCCGC CCCCTAGGGC GCGGGGAGGG GGCGGGGGGC TACGCGGGGC GGGGCCGGGC GGCGCCCGGG GTCCCCTCCC CCGCCCCCCT GACGTCAGCC CCCGACAGCG GCGAGTTCCT CACTTGGCTC GCGCCCTCCG TCGGGGAAGC TCGGGGCTCT GCACCCCAGT GGGCGCTCCT TCTTGCCAGA GTCCCCGATT TCCAGGCGCC CCGCGTGCGT GCAACTTCTT TGCGGGTGTG CAGCCTAGGT TTTAGAGTAT TCTGGGAACG GACTAGTCGG GTTGCTGCAG CAGCGAGCGG GAAGGGGTGG GGCCGAGCTT CTGCAGGACG CTGGGCCCGG CCTCCCGCAG GTGTTCGCTC TGGGTGCTGG ATGCTGGGTG CTGGAGTCCC GGCAGAGAGG CGCAGCCGGG GCGCATCCCC AACCCGTGCA TCCCGCGCCC GCCTGTTGCT GGAAAAGGCA GTTTCCCTAG CTGGAGGGGG CCGCCGACCC CTCCCCCTCC GCCTGGGCCT CACGCCAGTT TGGAGGTGAG CGAGGGAGGA GGCCGCTCCT GCTGGGGCTG GGCGTTGGCA AGGGCAGCGG GTGGTGTGGG TCTCCTTGCG CCTCCGGGTT TGACGGGATT ACAGGGGAAA GACAACAGAT GGAGAAGTTC TACAACAGTA ACAGCTTCTG TGGTCCACTA GAGTCAGGTG GAGAGAGCCT GGCACCTCGG AGCTTTCCTT TAAGCCATCG AGTAGACATG CTTTCCTGGG

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_023061, NM_001359530
UniProt ID Q8R2Y2
Synonyms 1-gicerin; AV025631; CD146; CD149; Muc18; s-endo; s-gicerin
Summary Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity).UniProtKB/Swiss-Prot Function
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA211277 Mcam CRISPRa kit - CRISPR gene activation of mouse melanoma cell adhesion molecule 1 kit
$1,657.00
KN309859BN Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859LP Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859RB Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN509859 Mcam - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products