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Mouse Mcam activation kit by CRISPRa

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SKU
GA211277
Mcam CRISPRa kit - CRISPR gene activation of mouse melanoma cell adhesion molecule
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

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Other products for "Mcam"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mcam
Locus ID 84004
Components

GA211277G1, Mcam gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211277G2, Mcam gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211277G3, Mcam gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_023061, NM_001359530
UniProt ID Q8R2Y2
Synonyms 1-gicerin; AV025631; CD146; CD149; Muc18; s-endo; s-gicerin
Summary Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN309859 Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859BN Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859LP Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309859RB Mcam - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN509859 Mcam - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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