mtTFA (TFAM) Human Gene Knockout Kit (CRISPR)

SKU
KN215488BN
TFAM - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol mtTFA
Locus ID 7019
Components

KN215488G1, mtTFA gRNA vector 1 in pCas-Guide CRISPR vector

KN215488G2, mtTFA gRNA vector 2 in pCas-Guide CRISPR vector

KN215488BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001270782, NM_003201, NM_012251, NR_073073
UniProt ID Q00059
Synonyms MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3
Summary This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2012
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Other Versions
SKU Description Size Price
GA104828 TFAM CRISPRa kit - CRISPR gene activation of human transcription factor A, mitochondrial 1 kit
$1,657.00
KN215488 TFAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215488LP TFAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215488RB TFAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415488 TFAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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