IGF1 Receptor (IGF1R) Human Gene Knockout Kit (CRISPR)

SKU
KN214928LP
IGF1R - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol IGF1 Receptor
Locus ID 3480
Components

KN214928G1, IGF1 Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN214928G2, IGF1 Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN214928LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000875, NM_001291858
UniProt ID P08069
Synonyms CD221; IGFIR; IGFR; JTK13
Summary This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, May 2014
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Other Versions
SKU Description Size Price
GA102349 IGF1R CRISPRa kit - CRISPR gene activation of human insulin like growth factor 1 receptor 1 kit
$1,657.00
KN214928 IGF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214928BN IGF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214928RB IGF1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414928 IGF1R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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