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BCDIN3D Human Gene Knockout Kit (CRISPR)

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SKU
KN208818LP
BCDIN3D - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "BCDIN3D or NM_181708.3"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol BCDIN3D
Locus ID 144233
Components

KN208818G1, BCDIN3D gRNA vector 1 in pCas-Guide CRISPR vector

KN208818G2, BCDIN3D gRNA vector 2 in pCas-Guide CRISPR vector

KN208818LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_181708
UniProt ID Q7Z5W3
Synonyms BCDIN3 domain containing
Summary This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. provided by RefSeq, Apr 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA115487 BCDIN3D CRISPRa kit - CRISPR gene activation of human BCDIN3 domain containing RNA methyltransferase 1 kit
$1,657.00
KN208818 BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208818BN BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208818RB BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408818 BCDIN3D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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