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Human BCDIN3D activation kit by CRISPRa

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SKU
GA115487
BCDIN3D CRISPRa kit - CRISPR gene activation of human BCDIN3 domain containing RNA methyltransferase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC208818 BCDIN3D (Myc-DDK-tagged)-Human BCDIN3 domain containing (BCDIN3D)
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Other products for "BCDIN3D"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCDIN3D
Locus ID 144233
Components

GA115487G1, BCDIN3D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115487G2, BCDIN3D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115487G3, BCDIN3D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_181708
UniProt ID Q7Z5W3
Synonyms BCDIN3 domain containing
Summary This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. provided by RefSeq, Apr 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN208818 BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208818BN BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208818LP BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208818RB BCDIN3D - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408818 BCDIN3D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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