CD3E Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | CD3E |
| Locus ID | 916 |
| Components |
KN208276G1, CD3E gRNA vector 1 in pCas-Guide CRISPR vector KN208276G2, CD3E gRNA vector 2 in pCas-Guide CRISPR vector KN208276RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_000733 |
| UniProt ID | P07766 |
| Synonyms | IMD18; T3E; TCRE |
| Summary | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA100644 | CD3E CRISPRa kit - CRISPR gene activation of human CD3e molecule | 1 kit |
$1,657.00
|
|
| KN208276 | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN208276BN | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN208276LP | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN408276 | CD3E - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.