Human CD3E activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CD3E |
| Locus ID | 916 |
| Components |
GA100644G1, CD3E gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100644G2, CD3E gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100644G3, CD3E gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_000733 |
| UniProt ID | P07766 |
| Synonyms | IMD18; T3E; TCRE |
| Summary | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN208276 | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN208276BN | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN208276LP | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN208276RB | CD3E - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN408276 | CD3E - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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