Osteopontin (SPP1) Human Gene Knockout Kit (CRISPR)

SKU
KN204803BN
SPP1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Osteopontin
Locus ID 6696
Components

KN204803G1, Osteopontin gRNA vector 1 in pCas-Guide CRISPR vector

KN204803G2, Osteopontin gRNA vector 2 in pCas-Guide CRISPR vector

KN204803BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000582, NM_001040058, NM_001040060, NM_001251829, NM_001251830
UniProt ID P10451
Synonyms BNSP; BSPI; ETA-1; OPN
Summary The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2011
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Other Versions
SKU Description Size Price
GA104596 SPP1 CRISPRa kit - CRISPR gene activation of human secreted phosphoprotein 1 1 kit
$1,657.00
KN204803 SPP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204803LP SPP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204803RB SPP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404803 SPP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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