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beta 2 Adrenergic Receptor (ADRB2) Human Gene Knockout Kit (CRISPR)

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SKU
KN204499RB
ADRB2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "beta 2 Adrenergic Receptor or NM_000024"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol beta 2 Adrenergic Receptor
Locus ID 154
Components

KN204499G1, beta 2 Adrenergic Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN204499G2, beta 2 Adrenergic Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN204499RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000024
UniProt ID P07550
Synonyms ADRB2R; ADRBR; B2AR; BAR; BETA2AR
Summary This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. provided by RefSeq, Oct 2019
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Other Versions
SKU Description Size Price
GA100107 ADRB2 CRISPRa kit - CRISPR gene activation of human adrenoceptor beta 2 1 kit
$1,657.00
KN204499 ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204499BN ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204499LP ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404499 ADRB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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