Human beta 2 Adrenergic Receptor (ADRB2) activation kit by CRISPRa

SKU
GA100107
ADRB2 CRISPRa kit - CRISPR gene activation of human adrenoceptor beta 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ADRB2
Locus ID 154
Components

GA100107G1, beta 2 Adrenergic Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100107G2, beta 2 Adrenergic Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100107G3, beta 2 Adrenergic Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000024
UniProt ID P07550
Synonyms ADRB2R; ADRBR; B2AR; BAR; BETA2AR
Summary This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. provided by RefSeq, Oct 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN204499 ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204499BN ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204499LP ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204499RB ADRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404499 ADRB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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