SIRT6 Human Gene Knockout Kit (CRISPR)

SKU
KN202833RB
SIRT6 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol SIRT6
Locus ID 51548
Components

KN202833G1, SIRT6 gRNA vector 1 in pCas-Guide CRISPR vector

KN202833G2, SIRT6 gRNA vector 2 in pCas-Guide CRISPR vector

KN202833RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001193285, NM_001321058, NM_001321059, NM_001321060, NM_001321061, NM_001321062, NM_001321063, NM_001321064, NM_016539
UniProt ID Q8N6T7
Synonyms SIR2L6
Summary This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Mar 2016
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Other Versions
SKU Description Size Price
GA109867 SIRT6 CRISPRa kit - CRISPR gene activation of human sirtuin 6 1 kit
$1,657.00
KN202833 SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202833BN SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202833LP SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402833 SIRT6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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