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Human SIRT6 activation kit by CRISPRa

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SKU
GA109867
SIRT6 CRISPRa kit - CRISPR gene activation of human sirtuin 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA503670 SIRT6 mouse monoclonal antibody, clone OTI1G3 (formerly 1G3) 100 ul
$447.00
RC202833 SIRT6 (Myc-DDK-tagged)-Human sirtuin 6 (SIRT6), transcript variant 1
10 ug
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Other products for "SIRT6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SIRT6
Locus ID 51548
Components

GA109867G1, SIRT6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109867G2, SIRT6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109867G3, SIRT6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001193285, NM_001321058, NM_001321059, NM_001321060, NM_001321061, NM_001321062, NM_001321063, NM_001321064, NM_016539
UniProt ID Q8N6T7
Synonyms SIR2L6
Summary This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Mar 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN202833 SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202833BN SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202833LP SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202833RB SIRT6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402833 SIRT6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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