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c-Myc (MYC) Human Gene Knockout Kit (CRISPR)

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SKU
KN201611LP
MYC - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "c-Myc or NM_002467"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol c-Myc
Locus ID 4609
Components

KN201611G1, c-Myc gRNA vector 1 in pCas-Guide CRISPR vector

KN201611G2, c-Myc gRNA vector 2 in pCas-Guide CRISPR vector

KN201611LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002467, NM_001354870
UniProt ID P01106
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Summary This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA103055 MYC CRISPRa kit - CRISPR gene activation of human MYC proto-oncogene, bHLH transcription factor 1 kit
$1,657.00
KN201611 MYC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201611BN MYC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201611RB MYC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401611 MYC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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