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Human p53 (TP53) activation kit by CRISPRa

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SKU
GA104942
TP53 CRISPRa kit - CRISPR gene activation of human tumor protein p53
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA502870 TP53 mouse monoclonal antibody, clone OTI5E2 (formerly 5E2)
100 ul
$447.00
RC200003 TP53 (Myc-DDK-tagged)-Human tumor protein p53 (TP53), transcript variant 1 10 ug
$457.00

Other products for "TP53"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TP53
Locus ID 7157
Components

GA104942G1, p53 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104942G2, p53 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104942G3, p53 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000546, NM_001126112, NM_001126113, NM_001126114, NM_001126115, NM_001126116, NM_001126117, NM_001126118, NM_001276695, NM_001276696, NM_001276697, NM_001276698, NM_001276699, NM_001276760, NM_001276761
UniProt ID P04637
Synonyms BCC7; LFS1; P53; TRP53
Summary This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). provided by RefSeq, Dec 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN200003 TP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200003BN TP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200003LP TP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200003RB TP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400003 TP53 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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