OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human E Cadherin (CDH1) activation kit by CRISPRa

Be the first to review this product
SKU
GA100713
CDH1 CRISPRa kit - CRISPR gene activation of human cadherin 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA800691 CDH1 (E Cadherin) mouse monoclonal antibody, clone OTI2F9 (formerly 2F9) 100 ul
$447.00
RC220731 CDH1 (Myc-DDK-tagged)-Human cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
10 ug
$808.00

Other products for "CDH1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDH1
Locus ID 999
Components

GA100713G1, E Cadherin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100713G2, E Cadherin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100713G3, E Cadherin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001317184, NM_001317185, NM_001317186, NM_004360
UniProt ID P12830
Synonyms Arc-1; CD324; CDHE; ECAD; LCAM; UVO
Summary This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. provided by RefSeq, Nov 2015
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN220731 CDH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220731BN CDH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220731LP CDH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220731RB CDH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420731 CDH1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products