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E Cadherin (CDH1) Mouse Monoclonal Antibody [Clone ID: OTI2F9]

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SKU
TA800691
CDH1 (E Cadherin) mouse monoclonal antibody, clone OTI2F9 (formerly 2F9)
Size:
100 ul
Conjugation:
Unconjugated
  $447.00
In Stock*
Bulk/Customize

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View other "E Cadherin or NM_004360" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2F9
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 94.8 kDa
Gene Name cadherin 1
Database Link
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. provided by RefSeq, Jul 2008
Synonyms Arc-1; CD324; CDHE; ECAD; LCAM; UVO
Reference Data
Protein Categories Cancer: Endocrine, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Head and Neck, CD Markers, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer
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Other "OTI2F9" antibodies (2)
SKU Description Size Price
TA600197 CDH1 mouse monoclonal capture antibody, validated for Luminex assays 100 ug
$458.00
TA700197 CDH1 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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