pLenti-Cas9

SKU
GE100028
pLenti-Cas9 vector, Cas9 in lenti vector (10 ug)
  $880.00
In Stock*
Specifications
Specifications
Product Data
Function Cas9 only vectors
Features

Cas9 only vector in lenti backbone

  • 3rd generation Lenti vector, ideal for hard-to-transfect cells
  • Cas9 under CMV promoter for mammalian expression after transfection or transduction
  • Lenti particles can be produced using high efficiency lenti packaging kits
  • E. Coli selection: chloramphenicol (34 ug/mL)
Download Vector Sequence
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS.
Storage Please store at -20°C for long term storage.
Stability The dried and the suspended DNA are stable for one year from date of shipping when stored at -20°C.
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Documents
Resources

file-alt Citations

Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2
Constantinescu-Bercu, Grassi, Frontini et al
Elife (2020) 9 DOI: 10.7554/eLife.53353
AI Summary: In this study, OriGene products—specifically, the SLC44A2 cDNA clone (RC208706) and SLC44A2 shRNA lentiviral particles (TL313482V)—were used to manipulate and study SLC44A2 expression, enabling the authors to elucidate its role in platelet-mediated neutrophil extracellular trap (NET) formation.
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A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance
Ceccaldi, O'Connor, Mouw et al
Cancer Res. (2015) 75 (4), 628-34 DOI: 10.1158/0008-5472.CAN-14-2593
AI Summary: In this study, OriGene’s pLenti vector was used to complement ERCC4-deficient cell lines with wild-type or mutant ERCC4, enabling functional analysis of NER gene alterations in ovarian cancer platinum sensitivity and PARP inhibitor resistance.
Snippet: ERCC6-deficient line was complemented with either wild-type or mutant N-terminal Flag-tagged ERCC6, cloned in a pOZ vector. The ERCC4-deficient line was complemented with C-terminal Myc-tagged wild-type or mutant ERCC4, cloned in a pLenti vector (Origene ... Cite SaveSaving
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
Weygant, Qu, Berry et al
Mol. Cancer (2014) 13 (1), 103 DOI: 10.1186/1476-4598-13-103
Cited by 117
AI Summary: OriGene’s human DCLK1 isoform short-α cDNA tagged with turboGFP was used to generate a kinase-dead DCLK1 mutant, enabling the study of DCLK1 kinase activity’s role in cancer cell behavior in this research.
Snippet: Human DCLK1 isoform short-α cDNA tagged with turboGFP (tGFP) (Origene) was used to create a kinase-dead mutant, in which the lysine at residue 419 was substituted with an arginine by site-directed mutagenesis using the QuickChange II mutagenesis kit (Agilent Technologies)
Showing 1-3 of 3 papers.
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