Stim1 Mouse Gene Knockout Kit (CRISPR)

SKU
KN316864RB
Stim1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Stim1
Locus ID 20866
Components

KN316864G1, Stim1 gRNA vector 1 in pCas-Guide CRISPR vector

KN316864G2, Stim1 gRNA vector 2 in pCas-Guide CRISPR vector

KN316864RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_009287
UniProt ID P70302
Synonyms SIM
Summary Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.UniProtKB/Swiss-Prot Function
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Other Versions
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GA204136 Stim1 CRISPRa kit - CRISPR gene activation of mouse stromal interaction molecule 1 1 kit
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KN316864 Stim1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN316864BN Stim1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN316864LP Stim1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN516864 Stim1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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