Mouse Stim1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Stim1 |
| Locus ID | 20866 |
| Components |
GA204136G1, Stim1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204136G2, Stim1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204136G3, Stim1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_009287 |
| UniProt ID | P70302 |
| Synonyms | SIM |
| Summary | Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN316864 | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN316864BN | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN316864LP | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN316864RB | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN516864 | Stim1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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