Stim1 Mouse Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | Stim1 |
| Locus ID | 20866 |
| Components |
KN316864G1, Stim1 gRNA vector 1 in pCas-Guide CRISPR vector KN316864G2, Stim1 gRNA vector 2 in pCas-Guide CRISPR vector KN316864LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_009287 |
| UniProt ID | P70302 |
| Synonyms | SIM |
| Summary | Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.UniProtKB/Swiss-Prot Function |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA204136 | Stim1 CRISPRa kit - CRISPR gene activation of mouse stromal interaction molecule 1 | 1 kit |
$1,657.00
|
|
| KN316864 | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN316864BN | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN316864RB | Stim1 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN516864 | Stim1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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