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Sptlc3 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN316688LP
Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR206971 Sptlc3 (Myc-DDK-tagged) - Mouse serine palmitoyltransferase, long chain base subunit 3 (Sptlc3)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "Sptlc3 or BC094496"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Sptlc3
Locus ID 228677
Components

KN316688G1, Sptlc3 gRNA vector 1 in pCas-Guide CRISPR vector

KN316688G2, Sptlc3 gRNA vector 2 in pCas-Guide CRISPR vector

KN316688LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_175467, NM_001356507
UniProt ID Q8BG54
Synonyms C130053K05Rik
Summary Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2. The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
GA214019 Sptlc3 CRISPRa kit - CRISPR gene activation of mouse serine palmitoyltransferase, long chain base subunit 3 1 kit
$1,657.00
KN316688 Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN316688BN Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN316688RB Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN516688 Sptlc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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