Mouse Sptlc3 activation kit by CRISPRa

SKU
GA214019
Sptlc3 CRISPRa kit - CRISPR gene activation of mouse serine palmitoyltransferase, long chain base subunit 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sptlc3
Locus ID 228677
Components

GA214019G1, Sptlc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214019G2, Sptlc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214019G3, Sptlc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_175467, NM_001356507
UniProt ID Q8BG54
Synonyms C130053K05Rik
Summary Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2. The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN316688 Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN316688BN Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN316688LP Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN316688RB Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN516688 Sptlc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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