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Ppargc1a Mouse Gene Knockout Kit (CRISPR)

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SKU
KN313676BN
Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Ppargc1a
Locus ID 19017
Components

KN313676G1, Ppargc1a gRNA vector 1 in pCas-Guide CRISPR vector

KN313676G2, Ppargc1a gRNA vector 2 in pCas-Guide CRISPR vector

KN313676BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_008904, NR_027710, NR_132764
UniProt ID O70343
Synonyms A830037N07Rik; ENSMUSG00000079510; Gm11133; PGC-1; Pgc-1alpha; Pgc1; Pgco1; PPARGC-1-alpha; Ppargc1
Summary This gene encodes a transcriptional coactivator that induces and coordinates gene expression regulating mitochondrial biogenesis, respiration, hepatic gluconeogenesis, thermogenic program in brown fat and muscle fiber-type switching. Mice lacking the encoded protein exhibit reduced thermogenic capacity, hyperactivity and resistance to diet-induced obesity. Mice lacking the encoded protein specifically in the heart exhibit peripartum cardiomyopathy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
GA203342 Ppargc1a CRISPRa kit - CRISPR gene activation of mouse peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 1 kit
$1,657.00
KN313676 Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313676LP Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313676RB Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513676 Ppargc1a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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