Mouse Ppargc1a activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Ppargc1a |
| Locus ID | 19017 |
| Components |
GA203342G1, Ppargc1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203342G2, Ppargc1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203342G3, Ppargc1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_008904, NR_027710, NR_132764 |
| UniProt ID | O70343 |
| Synonyms | A830037N07Rik; ENSMUSG00000079510; Gm11133; PGC-1; Pgc-1alpha; Pgc1; Pgco1; PPARGC-1-alpha; Ppargc1 |
| Summary | This gene encodes a transcriptional coactivator that induces and coordinates gene expression regulating mitochondrial biogenesis, respiration, hepatic gluconeogenesis, thermogenic program in brown fat and muscle fiber-type switching. Mice lacking the encoded protein exhibit reduced thermogenic capacity, hyperactivity and resistance to diet-induced obesity. Mice lacking the encoded protein specifically in the heart exhibit peripartum cardiomyopathy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN313676 | Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN313676BN | Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN313676LP | Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN313676RB | Ppargc1a - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN513676 | Ppargc1a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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