Pparg Mouse Gene Knockout Kit (CRISPR)

SKU
KN313675RB
Pparg - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Pparg
Locus ID 19016
Components

KN313675G1, Pparg gRNA vector 1 in pCas-Guide CRISPR vector

KN313675G2, Pparg gRNA vector 2 in pCas-Guide CRISPR vector

KN313675RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001127330, NM_011146
UniProt ID P37238
Synonyms Nr1c3; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2
Summary This gene encodes a nuclear receptor protein belonging to the peroxisome proliferator-activated receptor (Ppar) family. The encoded protein is a ligand-activated transcription factor that is involved in the regulation of adipocyte differentiation and glucose homeostasis. The encoded protein forms a heterodimer with retinoid X receptors and binds to DNA motifs termed "peroxisome proliferator response elements" to either activate or inhibit gene expression. Mice lacking the encoded protein die at an embryonic stage due to severe defects in placental vascularization. When the embryos lacking this gene are supplemented with healthy placentas, the mutants survive to term, but succumb to lipodystrophy and multiple hemorrhages. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
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Other Versions
SKU Description Size Price
GA203341 Pparg CRISPRa kit - CRISPR gene activation of mouse peroxisome proliferator activated receptor gamma 1 kit
$1,657.00
KN313675 Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313675BN Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313675LP Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513675 Pparg - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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