Pparg Mouse Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | Pparg |
| Locus ID | 19016 |
| Components |
KN313675G1, Pparg gRNA vector 1 in pCas-Guide CRISPR vector KN313675G2, Pparg gRNA vector 2 in pCas-Guide CRISPR vector KN313675RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001127330, NM_011146 |
| UniProt ID | P37238 |
| Synonyms | Nr1c3; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2 |
| Summary | This gene encodes a nuclear receptor protein belonging to the peroxisome proliferator-activated receptor (Ppar) family. The encoded protein is a ligand-activated transcription factor that is involved in the regulation of adipocyte differentiation and glucose homeostasis. The encoded protein forms a heterodimer with retinoid X receptors and binds to DNA motifs termed "peroxisome proliferator response elements" to either activate or inhibit gene expression. Mice lacking the encoded protein die at an embryonic stage due to severe defects in placental vascularization. When the embryos lacking this gene are supplemented with healthy placentas, the mutants survive to term, but succumb to lipodystrophy and multiple hemorrhages. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015 |
| Shipping | Ambient |
Reviews
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA203341 | Pparg CRISPRa kit - CRISPR gene activation of mouse peroxisome proliferator activated receptor gamma | 1 kit |
$1,657.00
|
|
| KN313675 | Pparg - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN313675BN | Pparg - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN313675LP | Pparg - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN513675 | Pparg - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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