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Mouse Pparg activation kit by CRISPRa

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SKU
GA203341
Pparg CRISPRa kit - CRISPR gene activation of mouse peroxisome proliferator activated receptor gamma
  $1,657.00
4 Weeks*

Other products for "Pparg"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pparg
Locus ID 19016
Components

GA203341G1, Pparg gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203341G2, Pparg gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203341G3, Pparg gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001127330, NM_011146
UniProt ID P37238
Synonyms Nr1c3; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2
Summary This gene encodes a nuclear receptor protein belonging to the peroxisome proliferator-activated receptor (Ppar) family. The encoded protein is a ligand-activated transcription factor that is involved in the regulation of adipocyte differentiation and glucose homeostasis. The encoded protein forms a heterodimer with retinoid X receptors and binds to DNA motifs termed "peroxisome proliferator response elements" to either activate or inhibit gene expression. Mice lacking the encoded protein die at an embryonic stage due to severe defects in placental vascularization. When the embryos lacking this gene are supplemented with healthy placentas, the mutants survive to term, but succumb to lipodystrophy and multiple hemorrhages. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN313675 Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313675BN Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313675LP Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313675RB Pparg - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513675 Pparg - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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