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Drosha Mouse Gene Knockout Kit (CRISPR)

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SKU
KN304817BN
Drosha - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Drosha or BC088999"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Drosha
Locus ID 14000
Components

KN304817G1, Drosha gRNA vector 1 in pCas-Guide CRISPR vector

KN304817G2, Drosha gRNA vector 2 in pCas-Guide CRISPR vector

KN304817BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001130149, NM_026799
UniProt ID Q5HZJ0
Synonyms 1110013A17Rik; AI874853; Etohi2; Rn3; Rnasen
Summary Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA201307 Drosha CRISPRa kit - CRISPR gene activation of mouse drosha, ribonuclease type III 1 kit
$1,657.00
KN304817 Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304817LP Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304817RB Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504817 Drosha - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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