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Mouse Drosha activation kit by CRISPRa

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SKU
GA201307
Drosha CRISPRa kit - CRISPR gene activation of mouse drosha, ribonuclease type III
  $1,657.00
4 Weeks*

Other products for "Drosha"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Drosha
Locus ID 14000
Components

GA201307G1, Drosha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201307G2, Drosha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201307G3, Drosha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001130149, NM_026799
UniProt ID Q5HZJ0
Synonyms 1110013A17Rik; AI874853; Etohi2; Rn3; Rnasen
Summary Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN304817 Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304817BN Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304817LP Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304817RB Drosha - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504817 Drosha - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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