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Dll4 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN304622LP
Dll4 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR212151 Dll4 (Myc-DDK-tagged) - Mouse delta-like 4 (Drosophila) (Dll4)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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$265.00

Other products for "Dll4 or BC042497"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Dll4
Locus ID 54485
Components

KN304622G1, Dll4 gRNA vector 1 in pCas-Guide CRISPR vector

KN304622G2, Dll4 gRNA vector 2 in pCas-Guide CRISPR vector

KN304622LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_019454
UniProt ID Q9JI71
Synonyms Delta4
Summary Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (PubMed:22323600). During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA205720 Dll4 CRISPRa kit - CRISPR gene activation of mouse delta like canonical Notch ligand 4 1 kit
$1,657.00
KN304622 Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304622BN Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304622RB Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504622 Dll4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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