Mouse Dll4 activation kit by CRISPRa

SKU
GA205720
Dll4 CRISPRa kit - CRISPR gene activation of mouse delta like canonical Notch ligand 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dll4
Locus ID 54485
Components

GA205720G1, Dll4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205720G2, Dll4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205720G3, Dll4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_019454
UniProt ID Q9JI71
Synonyms Delta4
Summary Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (PubMed:22323600). During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN304622 Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304622BN Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304622LP Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304622RB Dll4 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504622 Dll4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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