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RFXANK Human Gene Knockout Kit (CRISPR)

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SKU
KN220744BN
RFXANK - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "RFXANK or NM_001278727"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol RFXANK
Locus ID 8625
Components

KN220744G1, RFXANK gRNA vector 1 in pCas-Guide CRISPR vector

KN220744G2, RFXANK gRNA vector 2 in pCas-Guide CRISPR vector

KN220744BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001278727, NM_001278728, NM_003721, NM_134440, NM_001370233, NM_001370235, NM_001370237, NM_001370238, NM_001370234, NM_001370236
UniProt ID O14593
Synonyms ANKRA1; BLS; F14150_1; RFX-B
Summary Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
GA105711 RFXANK CRISPRa kit - CRISPR gene activation of human regulatory factor X associated ankyrin containing protein 1 kit
$1,657.00
KN220744 RFXANK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220744LP RFXANK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220744RB RFXANK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420744 RFXANK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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