Human RFXANK activation kit by CRISPRa

SKU
GA105711
RFXANK CRISPRa kit - CRISPR gene activation of human regulatory factor X associated ankyrin containing protein
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RFXANK
Locus ID 8625
Components

GA105711G1, RFXANK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105711G2, RFXANK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105711G3, RFXANK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001278727, NM_001278728, NM_003721, NM_134440, NM_001370233, NM_001370235, NM_001370237, NM_001370238, NM_001370234, NM_001370236
UniProt ID O14593
Synonyms ANKRA1; BLS; F14150_1; RFX-B
Summary Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
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KN220744 RFXANK - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN220744BN RFXANK - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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