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HIF1 beta (ARNT) Human Gene Knockout Kit (CRISPR)

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SKU
KN216724RB
ARNT - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol HIF1 beta
Locus ID 405
Components

KN216724G1, HIF1 beta gRNA vector 1 in pCas-Guide CRISPR vector

KN216724G2, HIF1 beta gRNA vector 2 in pCas-Guide CRISPR vector

KN216724RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001197325, NM_001286035, NM_001286036, NM_001668, NM_178426, NM_178427, NM_001350224, NM_001350225, NM_001350226
UniProt ID P27540
Synonyms bHLHe2; HIF-1-beta; HIF-1beta; HIF1-beta; HIF1B; HIF1BETA; TANGO
Summary This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2013
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Documents
Resources
Other Versions
SKU Description Size Price
GA100294 ARNT CRISPRa kit - CRISPR gene activation of human aryl hydrocarbon receptor nuclear translocator 1 kit
$1,657.00
KN216724 ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724BN ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724LP ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416724 ARNT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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