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Human HIF1 beta (ARNT) activation kit by CRISPRa

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SKU
GA100294
ARNT CRISPRa kit - CRISPR gene activation of human aryl hydrocarbon receptor nuclear translocator
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA501147 ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1A1 (formerly 1A1) 100 ul
$447.00
RC216724 ARNT (Myc-DDK-tagged)-Human aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 1
10 ug
$722.00

Other products for "ARNT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARNT
Locus ID 405
Components

GA100294G1, HIF1 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100294G2, HIF1 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100294G3, HIF1 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001197325, NM_001286035, NM_001286036, NM_001668, NM_178426, NM_178427, NM_001350224, NM_001350225, NM_001350226
UniProt ID P27540
Synonyms bHLHe2; HIF-1-beta; HIF-1beta; HIF1-beta; HIF1B; HIF1BETA; TANGO
Summary This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN216724 ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724BN ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724LP ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724RB ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416724 ARNT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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