OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

HIF1 beta (ARNT) Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN216724LP
ARNT - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA501147 ARNT (HIF1 beta) mouse monoclonal antibody, clone OTI1A1 (formerly 1A1) 100 ul
$447.00
RC216724 ARNT (Myc-DDK-tagged)-Human aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 1
10 ug
$722.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "HIF1 beta or NM_001197325"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol HIF1 beta
Locus ID 405
Components

KN216724G1, HIF1 beta gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GACTACTGCCAACCCCGGTG

KN216724G2, HIF1 beta gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: AGGACTGGGGCGCCTCTAAA

KN216724LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

Homologous arm and Luciferase-Puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; Luciferase-Puro in green; Right arm in violet

GCTAATTTTG TATTTTTAGT AGAGACGGGG TTTCGCCATG TTGGCCAGGC TGGTTTCGAA CCCCTGGCCA CAGGTGATCC GGCCGCCTCG GCCTCCCAAA GTGCTGGGAT TACAGACGCG AGCCACCGCG CCCAGCCTAA AATACCCATT TTAATTGCAT TTCAATGACG TTACTCGGTC ATTGACCTCT TACGCAAGGA GGGCGAGATT AGGGAGACAG CTGGACTTCT TCCTCGCCCT CCCTTCACTG GACTGGCTGG CGCAGTGAGT AGCCCTGCCC TTGGACGATT TGGCATTTTC ATTGGTCAAT TTTTCTTAGG AGGCTGGCCG TGTGTTGACT CCGCCTACTA TATAGGCGGG GTCTCCCCGC CGCAGGGGCT GGGATGCTGG GGGCTGCTGA AGCCGCCATC TTGGATTCCG CGGTAGCGGA GGCGGCGGTC AGGCGCCGCT TCTGGGGAGT GGCCTTTCTT TTCCCCTCCC TCCCGGTTCG GTGGCGGCGG CTCCTCCCAC TGGGGGGGGG GGTGGCGCGG CGGCGGTGGC ATCTGCGGCC TGAGGGGACG CAGCTGGAGC TGAAGGCGCC GGGGCGGGGC GGGGGCCGCG AGAGACGGTG GGGGAGCGGT GACCTGGGGA GGGGCCCGAT CCCGGGGACT TGGGTAGACT CGAGTATACC CAAGGGAGCG AGGGGGCAGG TGGGAGTTGA GGGGGGCTCC CTGTCCTGAC CTCCGTTGGA GCGGCAGCCA GTGCGGGGCT GGCCCGCCCT CACTCCTCGG TCGGCGTCTG GTCTGTGATG TGGTCCTCTT TTAACCCTCT GCCCGCTGGA GCCGCTTGAT GCCGAAAACT GTAGGCAGAG TGTCTCGGTT TACTTTAAGA GTAGTTTGGA TTCATAAACC CTGGACCACA CTGCTCTTTA GTTGAGGCGT TGCTTCCAAA CATTTAAAGG TTTAGATTTT AATTTAAAAA ATAAAAAATG GACATTCTTT GATATATACG ACGTTTCTTT AGGCTGTTAC CTCCCACCCG CAACCCCCGT CCCCGTCTCC GTCCCCGGAC TATACTTTGA AACTTAGATC TTGTGTTAAG AGGGCCTGTA GGTCTTTGCC TGCTGAGGGC AGGGGTTTGT GTAATGGTTA TGGTTCCGGA CAGGTCTTTA

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001197325, NM_001286035, NM_001286036, NM_001668, NM_178426, NM_178427, NM_001350224, NM_001350225, NM_001350226
UniProt ID P27540
Synonyms bHLHe2; HIF-1-beta; HIF-1beta; HIF1-beta; HIF1B; HIF1BETA; TANGO
Summary This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2013
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA100294 ARNT CRISPRa kit - CRISPR gene activation of human aryl hydrocarbon receptor nuclear translocator 1 kit
$1,657.00
KN216724 ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724BN ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216724RB ARNT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416724 ARNT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products